Quaternary structure of pathological prion protein as a determining factor of strain-specific prion replication dynamics. (Q35018090)

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28 February 2020

title

Quaternary structure of pathological prion protein as a determining factor of strain-specific prion replication dynamics (English)

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Vincent Béringue

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author name string

Philippe Tixador

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Mohammed Moudjou

3

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Jérôme Chapuis

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Pierre Sibille

5

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Laetitia Herzog

6

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Fabienne Reine

7

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Emilie Jaumain

8

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Hubert Laude

9

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Human Rezaei

10

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publication date

10 October 2013

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28 February 2020

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volume

9

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issue

10

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28 February 2020

page(s)

e1003702

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Creative Commons Attribution 4.0 International

28 February 2020

copyright license

start time

10 October 2013

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April 2022 Public Data File from Crossref

copyright status

copyrighted

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8 July 2018

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8 July 2018

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8 July 2018

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8 July 2018

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8 July 2018

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8 July 2018

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8 July 2018

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Immobilized prion protein undergoes spontaneous rearrangement to a conformation having features in common with the infectious form

8 July 2018

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Prion diseases of humans and animals: their causes and molecular basis

8 July 2018

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8 July 2018

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8 July 2018

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Quantifying the kinetic parameters of prion replication.

8 July 2018

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Eight prion strains have PrP(Sc) molecules with different conformations

8 July 2018

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Evidence for the conformation of the pathologic isoform of the prion protein enciphering and propagating prion diversity

8 July 2018

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Disruption of prion rods generates 10-nm spherical particles having high alpha-helical content and lacking scrapie infectivity

8 July 2018

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Seeding "one-dimensional crystallization" of amyloid: a pathogenic mechanism in Alzheimer's disease and scrapie?

8 July 2018

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Distinct PrP properties suggest the molecular basis of strain variation in transmissible mink encephalopathy.

8 July 2018

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Oligomeric structure of caveolin: implications for caveolae membrane organization

8 July 2018

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Novel proteinaceous infectious particles cause scrapie

8 July 2018

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8 July 2018

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Scrapie prion liposomes and rods exhibit target sizes of 55,000 Da.

8 July 2018

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Physical properties of the Creutzfeldt-Jakob disease agent

8 July 2018

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Caveolin, a protein component of caveolae membrane coats

8 July 2018

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Partial purification of the scrapie agent from mouse brain by pressure disruption and zonal centrifugation in sucrose-sodium chloride gradients

8 July 2018

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Unusual resistance to ionizing radiation of the viruses of kuru, Creutzfeldt-Jakob disease, and scrapie

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Discriminating scrapie and bovine spongiform encephalopathy isolates by infrared spectroscopy of pathological prion protein

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Isolation and characterization of a proteinase K-sensitive PrPSc fraction.

21 January 2018

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Hydration and packing effects on prion folding and beta-sheet conversion. High pressure spectroscopy and pressure perturbation calorimetry studies

21 January 2018

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Structural insights into the function of human caveolin 1.

21 January 2018

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Average protein density is a molecular-weight-dependent function.

21 January 2018

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A comprehensive model for packing and hydration for amyloid fibrils of beta2-microglobulin

21 January 2018

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Preparation of soluble infectious samples from scrapie-infected brain: a new tool to study the clearance of transmissible spongiform encephalopathy agents during plasma fractionation

21 January 2018

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Efficient inhibition of prion replication by PrP-Fc(2) suggests that the prion is a PrP(Sc) oligomer.

21 January 2018

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Prion replication and secondary nucleation

21 January 2018

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The physical basis of how prion conformations determine strain phenotypes

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Competing pathways determine fibril morphology in the self-assembly of beta2-microglobulin into amyloid.

21 January 2018

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Elucidation of the molecular mechanism during the early events in immunoglobulin light chain amyloid fibrillation. Evidence for an off-pathway oligomer at acidic pH.

21 January 2018

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Endogenous prion protein conversion is required for prion-induced neuritic alterations and neuronal death

21 January 2018

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12 December 2020

Drug solubilizers to aid pharmacologists: amorphous cyclodextrin derivatives

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The association between PrP and infectivity in scrapie and BSE infected mouse brain

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Thermodynamic properties underlying the alpha-helix-to-beta-sheet transition, aggregation, and amyloidogenesis of polylysine as probed by calorimetry, densimetry, and ultrasound velocimetry

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Ultrastructures and strain comparison of under-glycosylated scrapie prion fibrils

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Quantitative precipitation of various 3-beta-hydroxysterols with digitonin

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Interaction of saponins with cholesterol, lecithin, and albumin

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10.1371/JOURNAL.PPAT.1003702

Identifiers

DOI

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28 February 2020

1 reference

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28 February 2020

PubMed publication ID

24130496

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