CXCR3-dependent CD4⁺ T cells are required to activate inflammatory monocytes for defense against intestinal infection (Q35018100)

5 August 2017

CXCR3-dependent CD4⁺ T cells are required to activate inflammatory monocytes for defense against intestinal infection (English)

1 reference

5 August 2017

Sara B Cohen

1

1 reference

5 August 2017

Kirk J Maurer

2

1 reference

5 August 2017

Charlotte E Egan

3

1 reference

5 August 2017

Steve Oghumu

4

1 reference

5 August 2017

Abhay R Satoskar

5

1 reference

5 August 2017

Eric Y Denkers

6

1 reference

5 August 2017

10 October 2013

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5 August 2017

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5 August 2017

9

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5 August 2017

e1003706

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5 August 2017

10

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Creative Commons Attribution 4.0 International

5 August 2017

start time

10 October 2013

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

describes a project that uses

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3795032/fullTextXML

inferred from PubMed Central ID database lookup

cites work

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Distinct populations of innate CD8+ T cells revealed in a CXCR3 reporter mouse

8 July 2018

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Combined action of nucleic acid-sensing Toll-like receptors and TLR11/TLR12 heterodimers imparts resistance to Toxoplasma gondii in mice

8 July 2018

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Recognition of profilin by Toll-like receptor 12 is critical for host resistance to Toxoplasma gondii

8 July 2018

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CXCR3 chemokine receptor-ligand interactions in the lymph node optimize CD4+ T helper 1 cell differentiation

8 July 2018

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Immune response and immunopathology during toxoplasmosis

8 July 2018

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Inflammation drives dysbiosis and bacterial invasion in murine models of ileal Crohn's disease

8 July 2018

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NK cell-derived interferon-γ orchestrates cellular dynamics and the differentiation of monocytes into dendritic cells at the site of infection

8 July 2018

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Generalized Lévy walks and the role of chemokines in migration of effector CD8+ T cells

8 July 2018

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Ly6G+ neutrophils are dispensable for defense against systemic Listeria monocytogenes infection

8 July 2018

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Toxoplasma gondii rhoptry kinase ROP16 activates STAT3 and STAT6 resulting in cytokine inhibition and arginase-1-dependent growth control

8 July 2018

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CD8α(+) dendritic cells are the critical source of interleukin-12 that controls acute infection by Toxoplasma gondii tachyzoites

8 July 2018

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8 July 2018

CXCR3 in T cell function

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CXCL10 is required to maintain T-cell populations and to control parasite replication during chronic ocular toxoplasmosis

8 July 2018

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Inflammatory monocytes but not neutrophils are necessary to control infection with Toxoplasma gondii in mice

8 July 2018

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Coordinated loading of IRG resistance GTPases on to the Toxoplasma gondii parasitophorous vacuole

8 July 2018

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Chemokines as novel therapeutic targets for inflammatory bowel disease

8 July 2018

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CCR2-dependent intraepithelial lymphocytes mediate inflammatory gut pathology during Toxoplasma gondii infection

8 July 2018

1 reference

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IP-10-mediated T cell homing promotes cerebral inflammation over splenic immunity to malaria infection

8 July 2018

1 reference

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Disruption of the Toxoplasma gondii parasitophorous vacuole by IFNgamma-inducible immunity-related GTPases (IRG proteins) triggers necrotic cell death

8 July 2018

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TLR adaptor MyD88 is essential for pathogen control during oral toxoplasma gondii infection but not adaptive immunity induced by a vaccine strain of the parasite

8 July 2018

1 reference

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Gr1(+) inflammatory monocytes are required for mucosal resistance to the pathogen Toxoplasma gondii

8 July 2018

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Chemokine receptor CXCR3 and its ligands CXCL9 and CXCL10 are required for the development of murine cerebral malaria

8 July 2018

1 reference

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CXCR3 axis: role in inflammatory bowel disease and its therapeutic implication

8 July 2018

1 reference

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IRG proteins: key mediators of interferon-regulated host resistance to intracellular pathogens

8 July 2018

1 reference

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Exacerbation of murine ileitis by Toll-like receptor 4 mediated sensing of lipopolysaccharide from commensal Escherichia coli

8 July 2018

1 reference

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IL-23-dependent IL-17 production is essential in neutrophil recruitment and activity in mouse lung defense against respiratory Mycoplasma pneumoniae infection

8 July 2018

1 reference

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Vacuolar and plasma membrane stripping and autophagic elimination of Toxoplasma gondii in primed effector macrophages

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3795032

CD11c- and CD11b-expressing mouse leukocytes transport single Toxoplasma gondii tachyzoites to the brain

8 July 2018

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TLR11 activation of dendritic cells by a protozoan profilin-like protein.

8 July 2018

1 reference

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Blood monocytes consist of two principal subsets with distinct migratory properties

8 July 2018

1 reference

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Toxoplasma gondii tachyzoites inhibit proinflammatory cytokine induction in infected macrophages by preventing nuclear translocation of the transcription factor NF-kappa B.

8 July 2018

1 reference

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Chemokine receptor 2 serves an early and essential role in resistance to Mycobacterium tuberculosis.

8 July 2018

1 reference

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CD27 is required for generation and long-term maintenance of T cell immunity

8 July 2018

1 reference

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Regulation and function of T-cell-mediated immunity during Toxoplasma gondii infection.

8 July 2018

1 reference

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The chemokine receptors CXCR3 and CCR5 mark subsets of T cells associated with certain inflammatory reactions

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3795032

Phenotypic and functional separation of memory and effector human CD8+ T cells

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3795032

Neutrophil receptors for interleukin-8 and related CXC chemokines

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3795032

Toxoplasma gondii induces a T-independent IFN-gamma response in natural killer cells that requires both adherent accessory cells and tumor necrosis factor-alpha.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3795032

Interferon-gamma: the major mediator of resistance against Toxoplasma gondii

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3795032

Synergistic role of CD4+ and CD8+ T lymphocytes in IFN-gamma production and protective immunity induced by an attenuated Toxoplasma gondii vaccine

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3795032

Cutting edge: MyD88 is required for resistance to Toxoplasma gondii infection and regulates parasite-induced IL-12 production by dendritic cells.

8 July 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PPAT.1003706

TNF/iNOS-producing dendritic cells mediate innate immune defense against bacterial infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PPAT.1003706

CCR2-dependent trafficking of F4/80dim macrophages and CD11cdim/intermediate dendritic cells is crucial for T cell recruitment to lungs infected with Mycobacterium tuberculosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PPAT.1003706

CXCR3-/- mice mount an efficient Th1 response but fail to control Leishmania major infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PPAT.1003706

Heat-killed body of lactobacillus brevis SBC8803 ameliorates intestinal injury in a murine model of colitis by enhancing the intestinal barrier function.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PPAT.1003706

Interleukin-15-dependent NKp46+ innate lymphoid cells control intestinal inflammation by recruiting inflammatory monocytes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PPAT.1003706

Lack of CXCR3 delays the development of hepatic inflammation but does not impair resistance to Leishmania donovani.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PPAT.1003706

CD27low CD4 T lymphocytes that accumulate in the mouse lungs during mycobacterial infection differentiate from CD27high precursors in situ, produce IFN-gamma, and protect the host against tuberculosis infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PPAT.1003706

TNF-alpha, nitric oxide and IFN-gamma are all critical for development of necrosis in the small intestine and early mortality in genetically susceptible mice infected perorally with Toxoplasma gondii

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PPAT.1003706

Gram-negative bacteria aggravate murine small intestinal Th1-type immunopathology following oral infection with Toxoplasma gondii.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PPAT.1003706

CXCR2 deficiency confers impaired neutrophil recruitment and increased susceptibility during Toxoplasma gondii infection.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PPAT.1003706

Expression and regulation of the chemokine receptor CXCR3 on lymphocytes from normal and inflammatory bowel disease mucosa.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PPAT.1003706

Chemokine receptor CXCR3 expression in inflammatory bowel disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PPAT.1003706

Vaccination protects B cell-deficient mice against an oral challenge with mildly virulent Toxoplasma gondii

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PPAT.1003706

In the absence of endogenous IL-10, mice acutely infected with Toxoplasma gondii succumb to a lethal immune response dependent on CD4+ T cells and accompanied by overproduction of IL-12, IFN-gamma and TNF-alpha

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3795032

CD40/CD154 ligation is required for the development of acute ileitis following oral infection with an intracellular pathogen in mice

25 October 2018

1 reference

12 December 2020

Bone marrow macrophages process exogenous Toxoplasma gondii polypeptides for recognition by parasite-specific cytolytic T lymphocytes

1 reference

12 December 2020

In the absence of endogenous IFN-gamma, mice develop unimpaired IL-12 responses to Toxoplasma gondii while failing to control acute infection

1 reference

12 December 2020

Strong overexpression of CXCR3 axis components in childhood inflammatory bowel disease

1 reference

12 December 2020

IP-10 is critical for effector T cell trafficking and host survival in Toxoplasma gondii infection

1 reference

12 December 2020

Murine ileitis after intracellular parasite infection is controlled by TGF-beta-producing intraepithelial lymphocytes

1 reference

12 December 2020

10.1371/JOURNAL.PPAT.1003706

Identifiers

DOI

1 reference

5 August 2017

1 reference

5 August 2017

1 reference