Natural anti-CCR5 antibodies in HIV-infection and -exposure (Q35018133)

5 August 2017

10 references

23 March 2019

31 July 2019

3 August 2019

19 October 2019

27 November 2019

13 December 2019

15 December 2019

28 May 2020

1 July 2020

25 October 2022

Natural anti-CCR5 antibodies in HIV-infection and -exposure (English)

1 reference

human immunodeficiency virus infectious disease

5 August 2017

9 references

23 March 2019

31 July 2019

3 August 2019

19 October 2019

27 November 2019

13 December 2019

15 December 2019

28 May 2020

1 July 2020

cell surface receptor

1 reference

31 July 2019

1 reference

3 August 2019

Retroviridae infectious disease

1 reference

19 October 2019

1 reference

27 November 2019

1 reference

13 December 2019

1 reference

15 December 2019

Lucia Lopalco

1

0 references

language of work or name

1 reference

27 January 2011

11 references

Journal of Translational Medicine

5 August 2017

23 March 2019

31 July 2019

3 August 2019

19 October 2019

27 November 2019

13 December 2019

15 December 2019

28 May 2020

1 July 2020

25 October 2022

11 references

5 August 2017

23 March 2019

31 July 2019

3 August 2019

19 October 2019

27 November 2019

13 December 2019

15 December 2019

28 May 2020

1 July 2020

25 October 2022

9 Suppl 1

1 reference

5 August 2017

S4

1 reference

Creative Commons Attribution

5 August 2017

10 references

23 March 2019

31 July 2019

3 August 2019

19 October 2019

27 November 2019

13 December 2019

15 December 2019

28 May 2020

1 July 2020

25 October 2022

0 references

on focus list of Wikimedia project

ScienceSource

0 references

exact match

https://scigraph.springernature.com/pub.10.1186/1479-5876-9-s1-s4

0 references

cites work

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CCR5 antagonism in HIV infection: ways, effects, and side effects

8 July 2018

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Adult BM generates CD5+ B1 cells containing abundant N-region additions

8 July 2018

1 reference

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Herpes zoster pathogenesis and cell-mediated immunity and immunosenescence.

8 July 2018

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IgM in microbial infections: taken for granted?

8 July 2018

1 reference

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Human herpesvirus-6B induces expression of the human endogenous retrovirus K18-encoded superantigen

8 July 2018

1 reference

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Safety concerns about CCR5 as an antiviral target

8 July 2018

1 reference

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A pièce de resistance: how HIV-1 escapes small molecule CCR5 inhibitors

8 July 2018

1 reference

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CCR5 monoclonal antibodies for HIV-1 therapy

8 July 2018

1 reference

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A differentiation pathway for B1 cells in adult bone marrow

8 July 2018

1 reference

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Highly potent, fully recombinant anti-HIV chemokines: reengineering a low-cost microbicide

8 July 2018

1 reference

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Subgroup analyses of maraviroc in previously treated R5 HIV-1 infection

8 July 2018

1 reference

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Maraviroc for previously treated patients with R5 HIV-1 infection

8 July 2018

1 reference

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Antiviral activity of single-dose PRO 140, a CCR5 monoclonal antibody, in HIV-infected adults.

8 July 2018

1 reference

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HIV blocking antibodies following immunisation with chimaeric peptides coding a short N-terminal sequence of the CCR5 receptor

8 July 2018

1 reference

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Nature and functions of autoantibodies

8 July 2018

1 reference

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B lymphocytes: how they develop and function.

8 July 2018

1 reference

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Effects of retroviruses on host genome function.

8 July 2018

1 reference

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Neutralizing antibody and anti-retroviral drug sensitivities of HIV-1 isolates resistant to small molecule CCR5 inhibitors

8 July 2018

1 reference

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Peripheral B cell subsets

8 July 2018

1 reference

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Infection of macrophages and dendritic cells with primary R5-tropic human immunodeficiency virus type 1 inhibited by natural polyreactive anti-CCR5 antibodies purified from cervicovaginal secretions

8 July 2018

1 reference

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Safety, pharmacokinetics, and antiviral activity of HGS004, a novel fully human IgG4 monoclonal antibody against CCR5, in HIV-1-infected patients

8 July 2018

1 reference

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Pathogenesis of HIV disease: opportunities for new prevention interventions.

8 July 2018

1 reference

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A paradigm for virus-host coevolution: sequential counter-adaptations between endogenous and exogenous retroviruses

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3105504

Antibodies for HIV treatment and prevention: window of opportunity?

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3105504

Antiretroviral drug-based microbicides to prevent HIV-1 sexual transmission

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3105504

CCR5 blockade modulates inflammation and alloimmunity in primates

8 July 2018

1 reference

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Assessing theoretical risk and benefit suggested by genetic association studies of CCR5: experience in a drug development programme for maraviroc.

8 July 2018

1 reference

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The second extracellular loop of CCR5 contains the dominant epitopes for highly potent anti-human immunodeficiency virus monoclonal antibodies

8 July 2018

1 reference

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Novel CCR5 monoclonal antibodies with potent and broad-spectrum anti-HIV activities

8 July 2018

1 reference

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Natural mucosal antibodies reactive with first extracellular loop of CCR5 inhibit HIV-1 transport across human epithelial cells

8 July 2018

1 reference

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Role of B-1a cells in autoimmunity

8 July 2018

1 reference

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Transactivation of elements in the human endogenous retrovirus W family by viral infection

8 July 2018

1 reference

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Is autoimmunity a component of natural immunity to HIV?

8 July 2018

1 reference

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B cell clones that sustain long-term plasmablast growth in T-independent extrafollicular antibody responses

8 July 2018

1 reference

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Long-lasting CCR5 internalization by antibodies in a subset of long-term nonprogressors: a possible protective effect against disease progression

8 July 2018

1 reference

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Effects of immunization with CCR5-based cycloimmunogen on simian/HIVSF162P3 challenge

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3105504

Natural antibodies to CCR5 from breast milk block infection of macrophages and dendritic cells with primary R5-tropic HIV-1.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3105504

Induction of murine mucosal CCR5-reactive antibodies as an anti-human immunodeficiency virus strategy

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3105504

B1b lymphocytes confer T cell-independent long-lasting immunity

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3105504

Epstein-Barr virus latent membrane protein LMP-2A is sufficient for transactivation of the human endogenous retrovirus HERV-K18 superantigen

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3105504

Humoral immunity in HIV-1 exposure: cause or effect of HIV resistance?

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3105504

Induction of autoantibodies to CCR5 in macaques and subsequent effects upon challenge with an R5-tropic simian/human immunodeficiency virus

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3105504

8 July 2018

Mucosal AIDS vaccines

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3105504

Multiple active states and oligomerization of CCR5 revealed by functional properties of monoclonal antibodies

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3105504

Adaptation to blockade of human immunodeficiency virus type 1 entry imposed by the anti-CCR5 monoclonal antibody 2D7.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3105504

Antibodies to C-C chemokine receptor 5 in normal human IgG block infection of macrophages and lymphocytes with primary R5-tropic strains of HIV-1.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3105504

Anti-CCR5 antibodies in sera of HIV-positive individuals.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3105504

Potent, broad-spectrum inhibition of human immunodeficiency virus type 1 by the CCR5 monoclonal antibody PRO 140

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3105504

Mucosal and plasma IgA from HIV-1-exposed uninfected individuals inhibit HIV-1 transcytosis across human epithelial cells

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3105504

CCR5-reactive antibodies in seronegative partners of HIV-seropositive individuals down-modulate surface CCR5 in vivo and neutralize the infectivity of R5 strains of HIV-1 In vitro.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3105504

Differential inhibition of human immunodeficiency virus type 1 fusion, gp120 binding, and CC-chemokine activity by monoclonal antibodies to CCR5

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3105504

Epitope mapping of CCR5 reveals multiple conformational states and distinct but overlapping structures involved in chemokine and coreceptor function

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3105504

Induction of autoantibodies to mouse CCR5 with recombinant papillomavirus particles

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3105504

Chemokine receptor allelic polymorphisms: relationships to HIV resistance and disease progression

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3105504

The CCR5 receptor acts as an alloantigen in CCR5Delta32 homozygous individuals: identification of chemokineand HIV-1-blocking human antibodies

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3105504

Natural polyreactive secretory immunoglobulin A autoantibodies as a possible barrier to infection in humans

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3105504

CCR5 levels and expression pattern correlate with infectability by macrophage-tropic HIV-1, in vitro

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3105504

Neutralizing antiviral B cell responses

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3105504

Structure-function studies on a polyreactive (natural) autoantibody. Polyreactivity is dependent on somatically generated sequences in the third complementarity-determining region of the antibody heavy chain

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3105504

Natural auto- and polyreactive antibodies differing from antigen-induced antibodies in the H chain CDR3.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3105504

Two amino acid substitutions within the first external loop of CCR5 induce human immunodeficiency virus-blocking antibodies in mice and chickens

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3105504

An anti-CCR5 monoclonal antibody and small molecule CCR5 antagonists synergize by inhibiting different stages of human immunodeficiency virus type 1 entry

25 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3105504

Regulation of human endogenous retrovirus W protein expression by herpes simplex virus type 1: implications for multiple sclerosis

25 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3105504

Predictive value of anti-cell and anti-human immunodeficiency virus (HIV) humoral responses in HIV-1-exposed seronegative cohorts of European and Asian origin.

25 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3105504

Intranasal HIV-1-gp160-DNA/gp41 peptide prime-boost immunization regimen in mice results in long-term HIV-1 neutralizing humoral mucosal and systemic immunity.

25 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3105504

Rapid induction of splenic and peritoneal B-1a cells in adult mice by thymus-independent type-2 antigen

25 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3105504

Effect of a CCR5 inhibitor on viral loads in macaques dual-infected with R5 and X4 primate immunodeficiency viruses

25 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3105504

CCR5-specific mucosal IgA in saliva and genital fluids of HIV-exposed seronegative subjects

25 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3105504

A novel HIV-CCR5 receptor vaccine strategy in the control of mucosal SIV/HIV infection.

25 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3105504

Effect of heterosexual intercourse on mucosal alloimmunisation and resistance to HIV-1 infection.

25 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3105504

Transgenic expression of a human polyreactive Ig expressed in chronic lymphocytic leukemia generates memory-type B cells that respond to nonspecific immune activation

25 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3105504

The neutralizing antibody response against a conserved region of human immunodeficiency virus type 1 gp41 (amino acid residues 731-752) is uniquely directed against a conformational epitope

25 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3105504

HIV-1-resistance phenotype conferred by combination of two separate inherited mutations of CCR5 gene.

25 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3105504

Mucosal and plasma IgA from HIV-exposed seronegative individuals neutralize a primary HIV-1 isolate

25 October 2018

1 reference

12 December 2020

Increased levels of anti-CCR5 antibodies in sera from individuals immunized with allogeneic lymphocytes

1 reference

12 December 2020

Natural polyreactive IgA and IgM autoantibodies in human colostrum

1 reference

12 December 2020

Neutralization of HIV type 1 by alloimmune sera derived from polytransfused patients

1 reference

12 December 2020

Enhanced IgA class switching in marginal zone and B1 B cells relative to follicular/B2 B cells

1 reference

12 December 2020

10.1186/1479-5876-9-S1-S4

Identifiers

DOI

1 reference

PubMed ID

21284903

Dimensions Publication ID

5 August 2017

0 references

1 reference

5 August 2017

1 reference

PubMed ID

21284903