The anti-tumour activity of bisphosphonates. (Q35019664)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12470981%20AND%20SRC:MED&resulttype=core&format=json

15 December 2019

review article

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title

The anti-tumour activity of bisphosphonates (English)

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15 December 2019

2

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15 December 2019

author name string

H L Neville-Webbe

series ordinal

1

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15 December 2019

R E Coleman

series ordinal

3

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15 December 2019

publication date

1 December 2002

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15 December 2019

published in

Cancer Treatment Reviews

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15 December 2019

volume

28

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15 December 2019

issue

6

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15 December 2019

page(s)

305-319

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Bisphosphonates: from the laboratory to the clinic and back again

15 December 2019

cites work

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7 January 2021

Bisphosphonates are incorporated into adenine nucleotides by human aminoacyl-tRNA synthetase enzymes

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Clodronate decreases the frequency of skeletal metastases in women with breast cancer

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Long-term follow-up of a prospective, double-blind, placebo-controlled randomized trial of clodronate in multiple myeloma

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Reduction in new metastases in breast cancer with adjuvant clodronate treatment

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Detection of tumor cells in bone marrow of patients with primary breast cancer: a prognostic factor for distant metastasis

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Adjuvant clodronate treatment does not reduce the frequency of skeletal metastases in node-positive breast cancer patients: 5-year results of a randomized controlled trial

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7 January 2021

Effect of a newly developed bisphosphonate, YH529, on osteolytic bone metastases in nude mice

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Prophylactic treatment of skeletal metastases, tumor-induced osteolysis, and hypercalcemia in rats with the bisphosphonate Cl2MBP

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Molecular mechanisms of osteolytic bone metastases

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Bisphosphonates inhibit the adhesion of breast cancer cells to bone matrices in vitro

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MMP inhibition and downregulation by bisphosphonates.

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Visualization of bisphosphonate-induced caspase-3 activity in apoptotic osteoclasts in vitro

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Caspases: the executioners of apoptosis

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The bisphosphonate, zoledronic acid, induces apoptosis of breast cancer cells: evidence for synergy with paclitaxel

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7 January 2021

Apaf-1, a human protein homologous to C. elegans CED-4, participates in cytochrome c-dependent activation of caspase-3

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7 January 2021

The bisphosphonate zoledronic acid impairs Ras membrane [correction of impairs membrane] localisation and induces cytochrome c release in breast cancer cells

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7 January 2021

Farnesol and geranylgeraniol prevent activation of caspases by aminobisphosphonates: biochemical evidence for two distinct pharmacological classes of bisphosphonate drugs

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7 January 2021

Bisphosphonates induce apoptosis in human breast cancer cell lines

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7 January 2021

bcl-x, a bcl-2-related gene that functions as a dominant regulator of apoptotic cell death

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7 January 2021

Bisphosphonates regulate cell growth and gene expression in the UMR 106-01 clonal rat osteosarcoma cell line

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7 January 2021

The bisphosphonate pamidronate is a potent inhibitor of human osteosarcoma cell growth in vitro

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7 January 2021

Metalloproteinases: role in breast carcinogenesis, invasion and metastasis

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7 January 2021

Bisphosphonates inhibit stromelysin-1 (MMP-3), matrix metalloelastase (MMP-12), collagenase-3 (MMP-13) and enamelysin (MMP-20), but not urokinase-type plasminogen activator, and diminish invasion and migration of human malignant and endothelial cell

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7 January 2021

Zoledronate is a potent inhibitor of myeloma cell growth and secretion of IL-6 and MMP-1 by the tumoral environment

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7 January 2021

Inhibition of osteolytic bone metastasis of breast cancer by combined treatment with the bisphosphonate ibandronate and tissue inhibitor of the matrix metalloproteinase-2.

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Clinical significance of angiogenic factors in breast cancer

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7 January 2021

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7 January 2021

Vascular endothelial growth factor (VEGF) upregulates BCL-2 and inhibits apoptosis in human and murine mammary adenocarcinoma cells

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7 January 2021

Prognostic significance of vascular endothelial growth factor protein in node-negative breast carcinoma

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Vascular endothelial growth factor is of high prognostic value in node-negative breast carcinoma

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7 January 2021

Long-term follow-up and prognostic significance of angiogenic basic fibroblast growth factor (bFGF) expression in patients with breast cancer

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7 January 2021

Bone sialoprotein mediates human endothelial cell attachment and migration and promotes angiogenesis

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7 January 2021

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7 January 2021

Additive antitumor activities of taxoids in combination with the bisphosphonate ibandronate against invasion and adhesion of human breast carcinoma cells to bone

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7 January 2021

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7 January 2021

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Correlation of aromatase and cyclooxygenase gene expression in human breast cancer specimens

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A CRE-like sequence that binds CREB and contributes to cAMP-dependent regulation of the proximal promoter of the human aromatase P450 (CYP19) gene

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7 January 2021

Interleukin-6 and tumor necrosis factor alpha levels after bisphosphonates treatment in vitro and in patients with malignancy

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7 January 2021

10.1016/S0305-7372(02)00095-6

Identifiers

DOI

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12470981%20AND%20SRC:MED&resulttype=core&format=json

15 December 2019

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