Protein tyrosine phosphatases as drug targets: PTP1B and beyond (Q35020553)

5 August 2017

1 reference

title

Protein tyrosine phosphatases as drug targets: PTP1B and beyond (English)

1 reference

Rob Hooft van Huijsduijnen

5 August 2017

author

series ordinal

1

object named as

Rob Hooft van Huijsduijnen

1 reference

5 August 2017

2

Sébastien Wälchli

1 reference

5 August 2017

Mark Ibberson

3

1 reference

5 August 2017

Axel Harrenga

series ordinal

4

1 reference

5 August 2017

language of work or name

English

0 references

publication date

1 December 2002

1 reference

Expert Opinion on Therapeutic Targets

5 August 2017

published in

1 reference

5 August 2017

volume

6

1 reference

5 August 2017

issue

6

1 reference

5 August 2017

page(s)

637-647

1 reference

Structural and evolutionary relationships among protein tyrosine phosphatase domains

5 August 2017

cites work

1 reference

https://api.crossref.org/works/10.1517%2F14728222.6.6.637

Gathering STYX: phosphatase-like form predicts functions for unique protein-interaction domains

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.6.6.637

PTEN and myotubularin: novel phosphoinositide phosphatases

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.6.6.637

Negative regulators of cytokine signal transduction

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.6.6.637

Imaging sites of receptor dephosphorylation by PTP1B on the surface of the endoplasmic reticulum

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.6.6.637

Regulation of receptor tyrosine kinase signaling by protein tyrosine phosphatases

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.6.6.637

Identification of p130(cas) as a substrate for the cytosolic protein tyrosine phosphatase PTP-PEST.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.6.6.637

Association of PTP-PEST with the SH3 domain of p130cas; a novel mechanism of protein tyrosine phosphatase substrate recognition

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.6.6.637

Identification of p130cas as an in vivo substrate of receptor protein-tyrosine phosphatase alpha

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.6.6.637

Transmembrane tyrosine phosphatase LAR induces apoptosis by dephosphorylating and destabilizing p130Cas

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.6.6.637

Specific inhibition of FGF-induced MAPK activation by the receptor-like protein tyrosine phosphatase LAR

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.6.6.637

Protein tyrosine phosphatase 1B negatively regulates integrin signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.6.6.637

Inhibition of cell growth and spreading by stomach cancer-associated protein-tyrosine phosphatase-1 (SAP-1) through dephosphorylation of p130cas

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.6.6.637

Perinuclear localization of the protein-tyrosine phosphatase SHP-1 and inhibition of epidermal growth factor-stimulated STAT1/3 activation in A431 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.6.6.637

Protein tyrosine phosphatase epsilonC selectively inhibits interleukin-6- and interleukin- 10-induced JAK-STAT signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.6.6.637

A cytosolic protein-tyrosine phosphatase PTP1B specifically dephosphorylates and deactivates prolactin-activated STAT5a and STAT5b

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.6.6.637

A nuclear protein tyrosine phosphatase TC-PTP is a potential negative regulator of the PRL-mediated signaling pathway: dephosphorylation and deactivation of signal transducer and activator of transcription 5a and 5b by TC-PTP in nucleus

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.6.6.637

Protein-tyrosine phosphatase Shp-1 is a negative regulator of IL-4- and IL-13-dependent signal transduction.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.6.6.637

Regulation of the p70zap tyrosine protein kinase in T cells by the CD45 phosphotyrosine phosphatase

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.6.6.637

Hematopoietic cell phosphatase (HCP) regulates p56LCK phosphorylation and ZAP-70 binding to T cell receptor zeta chain

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.6.6.637

Epidermal growth factor receptor and the adaptor protein p52Shc are specific substrates of T-cell protein tyrosine phosphatase

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.6.6.637

TYK2 and JAK2 are substrates of protein-tyrosine phosphatase 1B

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.6.6.637

Overexpression of the LAR (leukocyte antigen-related) protein-tyrosine phosphatase in muscle causes insulin resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.6.6.637

Cell transformation and activation of pp60c-src by overexpression of a protein tyrosine phosphatase

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.6.6.637

Physical and functional interactions between receptor-like protein-tyrosine phosphatase alpha and p59fyn

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.6.6.637

Correlation between Src family member regulation by the protein-tyrosine-phosphatase CD45 and transmembrane signaling through the T-cell receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.6.6.637

Src kinase associates with a member of a distinct subfamily of protein-tyrosine phosphatases containing an ezrin-like domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.6.6.637

Identification of protein-tyrosine phosphatase 1B as the major tyrosine phosphatase activity capable of dephosphorylating and activating c-Src in several human breast cancer cell lines

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.6.6.637

Attenuation of adhesion-dependent signaling and cell spreading in transformed fibroblasts lacking protein tyrosine phosphatase-1B.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.6.6.637

EphrinB phosphorylation and reverse signaling: regulation by Src kinases and PTP-BL phosphatase

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.6.6.637

Pleiotrophin signals increased tyrosine phosphorylation of beta beta-catenin through inactivation of the intrinsic catalytic activity of the receptor-type protein tyrosine phosphatase beta/zeta

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.6.6.637

Insulin-mimetic effects of vanadate in primary cultures of rat hepatocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.6.6.637

Increased insulin sensitivity and obesity resistance in mice lacking the protein tyrosine phosphatase-1B gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.6.6.637

Fighting fat. New drugs against obesity in the pipeline

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.6.6.637

Protein tyrosine phosphatase 1B: a potential leptin resistance factor of obesity

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.6.6.637

Cdc25b phosphatase is required for resumption of meiosis during oocyte maturation

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.6.6.637

Absence of apparent phenotype in mice lacking Cdc25C protein phosphatase

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.6.6.637

Ptprj is a candidate for the mouse colon-cancer susceptibility locus Scc1 and is frequently deleted in human cancers

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.6.6.637

Altered podocyte structure in GLEPP1 (Ptpro)-deficient mice associated with hypertension and low glomerular filtration rate

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.6.6.637

Transgenic mice deficient in the LAR protein-tyrosine phosphatase exhibit profound defects in glucose homeostasis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.6.6.637

Hematopoietic protein tyrosine phosphatase suppresses extracellular stimulus-regulated kinase activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.6.6.637

A gene mutated in X-linked myotubular myopathy defines a new putative tyrosine phosphatase family conserved in yeast

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.6.6.637

Charcot-Marie-Tooth type 4B is caused by mutations in the gene encoding myotubularin-related protein-2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.6.6.637

Pten is essential for embryonic development and tumour suppression

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.6.6.637

PTEN, a unique tumor suppressor gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.6.6.637

21 January 2018

Identifiers

DOI

10.1517/14728222.6.6.637

1 reference

5 August 2017

1 reference