A high-frequency polymorphism in exon 6 of the CD45 tyrosine phosphatase gene (PTPRC) resulting in altered isoform expression. (Q35022603)

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3 November 2019

title

A high-frequency polymorphism in exon 6 of the CD45 tyrosine phosphatase gene (PTPRC) resulting in altered isoform expression (English)

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3 November 2019

10

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3 November 2019

Nadira Yuldasheva

8

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3 November 2019

Peter Beverley

11

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3 November 2019

Elma Z Tchilian

12

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3 November 2019

author name string

Tara Stanton

1

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3 November 2019

Sally Boxall

2

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3 November 2019

Kouzo Hirai

3

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3 November 2019

Ritu Dawes

4

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3 November 2019

Susan Tonks

5

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3 November 2019

Tomoyo Yasui

6

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3 November 2019

Yasushi Kanaoka

7

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3 November 2019

Osamu Ishiko

9

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3 November 2019

language of work or name

English

0 references

publication date

25 April 2003

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Proceedings of the National Academy of Sciences of the United States of America

3 November 2019

published in

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3 November 2019

volume

100

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3 November 2019

issue

10

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3 November 2019

page(s)

5997-6002

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A novel mutation in PTPRC interferes with splicing and alters the structure of the human CD45 molecule

3 November 2019

cites work

1 reference

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Differential association of CD45 isoforms with CD4 and CD8 regulates the actions of specific pools of p56lck tyrosine kinase in T cell antigen receptor signal transduction

8 July 2018

1 reference

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Developmentally regulated changes in glucosidase II association with, and carbohydrate content of, the protein tyrosine phosphatase CD45

8 July 2018

1 reference

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CD45: new jobs for an old acquaintance

8 July 2018

1 reference

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A CD45 polymorphism associated with multiple sclerosis disrupts an exonic splicing silencer

8 July 2018

1 reference

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Alkaline-mediated differential interaction (AMDI): a simple automatable single-nucleotide polymorphism assay

8 July 2018

1 reference

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CD45 is a JAK phosphatase and negatively regulates cytokine receptor signalling

8 July 2018

1 reference

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A deletion in the gene encoding the CD45 antigen in a patient with SCID.

8 July 2018

1 reference

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Alternative pre-mRNA splicing: the logic of combinatorial control

8 July 2018

1 reference

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Characterization of the interaction between galectin-1 and lymphocyte glycoproteins CD45 and Thy-1

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=156315

Cell-specific glycoforms of sialoadhesin and CD45 are counter-receptors for the cysteine-rich domain of the mannose receptor

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=156315

Biochemical association of CD45 with the T cell receptor complex: regulation by CD45 isoform and during T cell activation

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=156315

Galectin-1, a natural ligand for the receptor-type protein tyrosine phosphatase CD45

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=156315

Concepts and principles of O-linked glycosylation

8 July 2018

1 reference

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High incidence and prevalence of multiple sclerosis in south east Scotland: evidence of a genetic predisposition

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=156315

CD45-null transgenic mice reveal a positive regulatory role for CD45 in early thymocyte development, in the selection of CD4+CD8+ thymocytes, and B cell maturation

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=156315

A unique CD45 glycoform recognized by the serum mannan-binding protein in immature thymocytes

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=156315

Normal B lymphocyte development but impaired T cell maturation in CD45-exon6 protein tyrosine phosphatase-deficient mice

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=156315

Identification of amino acids at the junction of exons 3 and 7 that are used for the generation of glycosylation-related human CD45RO and CD45RO-like antigen specificities.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=156315

Loss of CD45R and gain of UCHL1 reactivity is a feature of primed T cells

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=156315

Differential usage of three exons generates at least five different mRNAs encoding human leukocyte common antigens

8 July 2018

1 reference

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Integrity of the exon 6 sequence is essential for tissue-specific alternative splicing of human leukocyte common antigen pre-mRNA.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=156315

Consanguinity and multiple sclerosis in Orkney

8 July 2018

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The B lymphocyte adhesion molecule CD22 interacts with leukocyte common antigen CD45RO on T cells and alpha 2-6 sialyltransferase, CD75, on B cells

8 July 2018

1 reference

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Genetically determined lack of CD45R- T cells in healthy individuals. Evidence for a regulatory polymorphism of CD45R antigen expression

8 July 2018

1 reference

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Protein tyrosine phosphatase receptor-type C exon 4 gene mutation distribution in an Italian multiple sclerosis population

8 July 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0931490100

Does 77C-->G in PTPRC modify autoimmune disorders linked to the major histocompatibility locus?

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0931490100

PTPRC (CD45) is not associated with the development of multiple sclerosis in U.S. patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0931490100

A CD45 polymorphism associated with abnormal splicing is absent in African populations.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0931490100

Apoptosis of T cells mediated by galectin-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0931490100

An inactivating point mutation in the inhibitory wedge of CD45 causes lymphoproliferation and autoimmunity

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0931490100

Negative regulation of CD45 by differential homodimerization of the alternatively spliced isoforms

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0931490100

A point mutation in PTPRC is associated with the development of multiple sclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0931490100

Mutations in the tyrosine phosphatase CD45 gene in a child with severe combined immunodeficiency disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0931490100

A point mutation in CD45 may be associated with an increased risk of HIV-1 infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0931490100

21 January 2018

Identifiers

DOI

10.1073/PNAS.0931490100

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12716971%20AND%20SRC:MED&resulttype=core&format=json

3 November 2019

0 references

1 reference

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3 November 2019

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