Evaluation of the novel mitotic modulator ON 01910.Na in pancreatic cancer and preclinical development of an ex vivo predictive assay. (Q35023385)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19029951%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

title

Evaluation of the novel mitotic modulator ON 01910.Na in pancreatic cancer and preclinical development of an ex vivo predictive assay (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19029951%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

1 reference

15

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19029951%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

author name string

A Jimeno

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19029951%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

A Chan

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19029951%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

G Cusatis

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19029951%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

X Zhang

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19029951%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

J Wheelhouse

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19029951%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

A Solomon

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19029951%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

F Chan

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19029951%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

M Zhao

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19029951%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

S C Cosenza

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19029951%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

M V Ramana Reddy

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19029951%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

M A Rudek

11

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19029951%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

P Kulesza

12

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19029951%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

R C Donehower

13

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19029951%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

E P Reddy

14

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19029951%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

language of work or name

English

0 references

publication date

24 November 2008

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19029951%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19029951%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

volume

28

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19029951%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

issue

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19029951%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

page(s)

610-618

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19029951%20AND%20SRC:MED&resulttype=core&format=json

Phase I study of ON 01910.Na, a novel modulator of the Polo-like kinase 1 pathway, in adult patients with solid tumors.

17 January 2020

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3107737

Core signaling pathways in human pancreatic cancers revealed by global genomic analyses

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3107737

Mechanisms of asymmetric cell division: flies and worms pave the way.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3107737

Validation and implementation of a liquid chromatography/tandem mass spectrometry assay to quantitate ON 01910.Na, a mitotic progression modulator, in human plasma

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3107737

8 July 2018

Cancer statistics, 2007

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3107737

Assessment of gefitinib- and CI-1040-mediated changes in epidermal growth factor receptor signaling in HuCCT-1 human cholangiocarcinoma by serial fine needle aspiration

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3107737

Molecular alterations after Polo-like kinase 1 mRNA suppression versus pharmacologic inhibition in cancer cells

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3107737

C-fos assessment as a marker of anti-epidermal growth factor receptor effect

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3107737

Celecoxib leads to G2/M arrest by induction of p21 and down-regulation of cyclin B1 expression in a p53-independent manner

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3107737

Stable gene silencing of cyclin B1 in tumor cells increases susceptibility to taxol and leads to growth arrest in vivo

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3107737

Epidermal growth factor receptor dynamics influences response to epidermal growth factor receptor targeted agents

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3107737

ON01910, a non-ATP-competitive small molecule inhibitor of Plk1, is a potent anticancer agent.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3107737

American Society of Clinical Oncology Technology Assessment: chemotherapy sensitivity and resistance assays

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3107737

Chemotherapy sensitivity and resistance assays: a systematic review

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3107737

Active cyclin B1-Cdk1 first appears on centrosomes in prophase

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3107737

Use of chemotherapy plus a monoclonal antibody against HER2 for metastatic breast cancer that overexpresses HER2.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3107737

Polo-like kinases: positive regulators of cell division from start to finish.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3107737

PLK-1 asymmetry contributes to asynchronous cell division of C. elegans embryos.

8 July 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.424

Cyclin B1 overexpression and resistance to radiotherapy in head and neck squamous cell carcinoma.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3107737

Polo-like kinase-1 is a target of the DNA damage checkpoint

25 October 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.424

The relationship between cyclin B1 overexpression and lymph node metastasis in human colorectal cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.424

An in vivo platform for translational drug development in pancreatic cancer

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.424

Constitutive activation of cyclin B1-associated cdc2 kinase overrides p53-mediated G2-M arrest

31 March 2020

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/19029951

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/ONC.2008.424

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19029951%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19029951%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

PubMed publication ID

19029951

1 reference