Targeting epidermal growth factor receptor in head and neck cancer (Q35023988)

5 August 2017

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title

Targeting epidermal growth factor receptor in head and neck cancer (English)

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5 August 2017

head and neck carcinoma

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Allison Carter Ford

1

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PubMed ID

12478546

5 August 2017

Jennifer Rubin Grandis

series ordinal

2

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5 August 2017

1 January 2003

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5 August 2017

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5 August 2017

25

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5 August 2017

1

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5 August 2017

67-73

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Phase I trial and tumour localisation of the anti-EGFR monoclonal antibody ICR62 in head and neck or lung cancer

5 August 2017

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21 January 2018

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7 January 2021

Adjuvant chemotherapy for advanced head and neck squamous carcinoma. Final report of the Head and Neck Contracts Program

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7 January 2021

Global cancer statistics

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7 January 2021

Characterization, quantification, and potential clinical value of the epidermal growth factor receptor in head and neck squamous cell carcinomas

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7 January 2021

Expression of epidermal growth factor receptor and survival in upper aerodigestive tract cancer

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7 January 2021

A multifactorial approach including tumoural epidermal growth factor receptor, p53, thymidylate synthase and dihydropyrimidine dehydrogenase to predict treatment outcome in head and neck cancer patients receiving 5-fluorouracil

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7 January 2021

HER-2/neu oncogene characterization in head and neck squamous cell carcinoma

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7 January 2021

Demonstration of ligand-dependent signaling by the erbB-3 tyrosine kinase and its constitutive activation in human breast tumor cells

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7 January 2021

The relationship between human epidermal growth-like factor receptor expression and cellular transformation in NIH3T3 cells

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7 January 2021

Differential expression of epidermal growth factor-related proteins in human colorectal tumors

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7 January 2021

Prognostic significance of ERBB3 overexpression in oral squamous cell carcinoma

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7 January 2021

Two erbB-4 transcripts are expressed in normal breast and in most breast cancers

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7 January 2021

Detection of epidermal growth factor receptor gene amplification in human squamous cell carcinomas using fluorescence in situ hybridization.

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7 January 2021

Human epidermal growth factor receptor cDNA sequence and aberrant expression of the amplified gene in A431 epidermoid carcinoma cells

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7 January 2021

Triggering signaling cascades by receptor tyrosine kinases

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7 January 2021

A common nuclear signal transduction pathway activated by growth factor and cytokine receptors

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7 January 2021

Complex roles of Stat1 in regulating gene expression

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7 January 2021

Stat3: a STAT family member activated by tyrosine phosphorylation in response to epidermal growth factor and interleukin-6

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7 January 2021

Requirement of Stat3 but not Stat1 activation for epidermal growth factor receptor- mediated cell growth In vitro

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7 January 2021

Constitutive activation of Stat3 signaling abrogates apoptosis in squamous cell carcinogenesis in vivo

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7 January 2021

STAT signaling in head and neck cancer

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7 January 2021

Epidermal growth factor receptor--mediated stat3 signaling blocks apoptosis in head and neck cancer

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7 January 2021

Downmodulation of TGF-alpha protein expression with antisense oligonucleotides inhibits proliferation of head and neck squamous carcinoma but not normal mucosal epithelial cells

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7 January 2021

Levels of TGF-alpha and EGFR protein in head and neck squamous cell carcinoma and patient survival

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7 January 2021

Recombinant antibody toxins specific for ErbB2 and EGF receptor inhibit the in vitro growth of human head and neck cancer cells and cause rapid tumor regression in vivo

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7 January 2021

Pseudomonas aeruginosa exotoxin in mice: histopathology and serum enzyme changes

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7 January 2021

Clinical trial with escalating doses of the antiepidermal growth factor receptor humanized monoclonal antibody EMD 72 000 in patients with advanced squamous cell carcinoma of the larynx and hypopharynx

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7 January 2021

Cytosine arabinoside increases the binding of 125I-labelled epidermal growth factor and 125I-transferrin and enhances the in vitro targeting of human tumour cells with anti-(growth factor receptor) mAb

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7 January 2021

Inhibition of epidermal growth factor receptor gene expression and function decreases proliferation of head and neck squamous carcinoma but not normal mucosal epithelial cells

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7 January 2021

Head and neck cancer as a clinical model for molecular targeting of therapy: combining EGFR blockade with radiation

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7 January 2021

Phase I study of anti--epidermal growth factor receptor antibody cetuximab in combination with radiation therapy in patients with advanced head and neck cancer

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7 January 2021

Inhibition of epidermal-growth-factor-receptor-dependent signalling by tyrphostins A25 and AG1478 blocks growth and induces apoptosis in colorectal tumor cells in vitro

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7 January 2021

EGFR tyrosine kinase inhibitor AG1478 inhibits cell proliferation and arrests cell cycle in nasopharyngeal carcinoma cells

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7 January 2021

Inhibition of human squamous cell carcinoma growth in vivo by epidermal growth factor receptor antisense RNA transcribed from the U6 promoter

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7 January 2021

TGF-alpha antisense gene therapy inhibits head and neck squamous cell carcinoma growth in vivo

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7 January 2021

Targeting growth factor receptors: integration of novel therapeutics in the management of head and neck cancer

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7 January 2021

Lack of toxicity of EGFR antisense gene therapy

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7 January 2021

Retinoic acid normalizes the increased gene transcription rate of TGF-alpha and EGFR in head and neck cancer cell lines

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7 January 2021

Transforming growth factor-alpha: a surrogate endpoint biomarker?

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7 January 2021

Epidermal growth factor receptors as a target for cancer treatment: the emerging role of IMC-C225 in the treatment of lung and head and neck cancers

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7 January 2021

Monoclonal antibodies to target epidermal growth factor receptor-positive tumors: a new paradigm for cancer therapy

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7 January 2021

Dose-dependent access of murine anti-epidermal growth factor receptor monoclonal antibody to tumor cells in patients with advanced laryngeal and hypopharyngeal carcinoma

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7 January 2021

Identifiers

DOI

10.1002/HED.10224

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5 August 2017

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PubMed ID

12478546