EB1089, a synthetic analogue of vitamin D, induces apoptosis in breast cancer cells in vivo and in vitro (Q35028096)

5 August 2017

EB1089, a synthetic analogue of vitamin D, induces apoptosis in breast cancer cells in vivo and in vitro (English)

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5 August 2017

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James SY

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5 August 2017

Mercer E

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5 August 2017

Brady M

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5 August 2017

Binderup L

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5 August 2017

Colston KW

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5 August 2017

language of work or name

English

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publication date

1 November 1998

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British Journal of Pharmacology

5 August 2017

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5 August 2017

125

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5 August 2017

5

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5 August 2017

953-962

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bcl-2 in normal human breast and carcinoma, association with oestrogen receptor-positive, epidermal growth factor receptor-negative tumours and in situ cancer

5 August 2017

1 reference

https://api.crossref.org/works/10.1038%2FSJ.BJP.0702103

31P-NMR spectroscopy and histological studies of the response of rat mammary tumours to endocrine therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.BJP.0702103

A Novel Vitamin D3Analog, 22-Oxa-1, 25- Dihydroxyvitamin D3, Inhibits the Growth of Human Breast Cancerin Vitroandin Vivowithout Causing Hypercalcemia*

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.BJP.0702103

7 January 2021

Expression of the bcl-2 gene family in normal and malignant breast tissue: low bax-alpha expression in tumor cells correlates with resistance towards apoptosis

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https://api.crossref.org/works/10.1038%2FSJ.BJP.0702103

7 January 2021

Overexpression of the death-promoting gene bax-alpha which is downregulated in breast cancer restores sensitivity to different apoptotic stimuli and reduces tumor growth in SCID mice

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https://api.crossref.org/works/10.1038%2FSJ.BJP.0702103

7 January 2021

A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding

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https://api.crossref.org/works/10.1038%2FSJ.BJP.0702103

7 January 2021

Induction of the growth inhibitor IGF-binding protein 3 by p53

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https://api.crossref.org/works/10.1038%2FSJ.BJP.0702103

7 January 2021

Effects of synthetic vitamin D analogues on breast cancer cell proliferation in vivo and in vitro

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https://api.crossref.org/works/10.1038%2FSJ.BJP.0702103

7 January 2021

EB1089: a new vitamin D analogue that inhibits the growth of breast cancer cells in vivo and in vitro

1 reference

https://api.crossref.org/works/10.1038%2FSJ.BJP.0702103

7 January 2021

Growth inhibition of both MCF-7 and Hs578T human breast cancer cell lines by vitamin D analogues is associated with increased expression of insulin-like growth factor binding protein-3

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https://api.crossref.org/works/10.1038%2FSJ.BJP.0702103

7 January 2021

A family of ligands for the TNF receptor superfamily

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https://api.crossref.org/works/10.1038%2FSJ.BJP.0702103

7 January 2021

bcl-2, p53, and response to tamoxifen in estrogen receptor-positive metastatic breast cancer: a Southwest Oncology Group study

1 reference

https://api.crossref.org/works/10.1038%2FSJ.BJP.0702103

7 January 2021

1 alpha,25-Dihydroxyvitamin D3 and 1 alpha-hydroxyvitamin D3 prolong survival time of mice inoculated with myeloid leukemia cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.BJP.0702103

7 January 2021

Expression of Bcl-2 in human breast cancer: correlation between hormone receptor status, p53 protein accumulation and DNA strand breaks associated with apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.BJP.0702103

7 January 2021

Estrogen increases intracellular p26Bcl-2 to p21Bax ratios and inhibits taxol-induced apoptosis of human breast cancer MCF-7 cells

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https://api.crossref.org/works/10.1038%2FSJ.BJP.0702103

7 January 2021

Apoptosis. Breaking the ICE.

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https://api.crossref.org/works/10.1038%2FSJ.BJP.0702103

7 January 2021

Effects of a new synthetic vitamin D analogue, EB1089, on the oestrogen-responsive growth of human breast cancer cells

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https://api.crossref.org/works/10.1038%2FSJ.BJP.0702103

7 January 2021

Vitamin D derivatives in combination with 9-cis retinoic acid promote active cell death in breast cancer cells

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https://api.crossref.org/works/10.1038%2FSJ.BJP.0702103

7 January 2021

Effects of 1,25 dihydroxyvitamin D3 and its analogues on induction of apoptosis in breast cancer cells

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https://api.crossref.org/works/10.1038%2FSJ.BJP.0702103

7 January 2021

Cancer. p53, guardian of the genome

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https://api.crossref.org/works/10.1038%2FSJ.BJP.0702103

7 January 2021

EB 1089, a novel vitamin D analogue, has strong antiproliferative and differentiation inducing effects on cancer cells

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https://api.crossref.org/works/10.1038%2FSJ.BJP.0702103

7 January 2021

p53-dependent and p53-independent activation of apoptosis in mammary epithelial cells reveals a survival function of EGF and insulin.

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https://api.crossref.org/works/10.1038%2FSJ.BJP.0702103

7 January 2021

Tumor suppressor p53 is a direct transcriptional activator of the human bax gene

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https://api.crossref.org/works/10.1038%2FSJ.BJP.0702103

7 January 2021

Two distinct mechanisms alter p53 in breast cancer: mutation and nuclear exclusion

1 reference

https://api.crossref.org/works/10.1038%2FSJ.BJP.0702103

7 January 2021

Bcl-2 and the regulation of programmed cell death

1 reference

https://api.crossref.org/works/10.1038%2FSJ.BJP.0702103

7 January 2021

Overexpression of bax sensitizes human breast cancer MCF-7 cells to radiation-induced apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.BJP.0702103

7 January 2021

Nonradioactive labeling of oligonucleotides in vitro with the hapten digoxigenin by tailing with terminal transferase

1 reference

https://api.crossref.org/works/10.1038%2FSJ.BJP.0702103

7 January 2021

Induction of apoptosis by wild-type p53 in a human colon tumor-derived cell line.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.BJP.0702103

7 January 2021

Comparative effects of 1,25(OH)2D3 and EB1089 on cell cycle kinetics and apoptosis in MCF-7 breast cancer cells.

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https://api.crossref.org/works/10.1038%2FSJ.BJP.0702103

7 January 2021

Apoptotic regression of MCF-7 xenografts in nude mice treated with the vitamin D3 analog, EB1089.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.BJP.0702103

7 January 2021

Inhibition of insulin- and insulin-like growth factor-I-stimulated growth of human breast cancer cells by 1,25-dihydroxyvitamin D3 and the vitamin D3 analogue EB1089

1 reference

https://api.crossref.org/works/10.1038%2FSJ.BJP.0702103

7 January 2021

Apoptosis in toremifene-induced growth inhibition of human breast cancer cells in vivo and in vitro

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https://api.crossref.org/works/10.1038%2FSJ.BJP.0702103

7 January 2021

Programmed cell death: apoptosis and oncogenesis.

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https://api.crossref.org/works/10.1038%2FSJ.BJP.0702103

7 January 2021

Apoptosis: cell death in tissue regulation

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https://api.crossref.org/works/10.1038%2FSJ.BJP.0702103

7 January 2021

Vitamin D derivatives inhibit the mitogenic effects of IGF-I on MCF-7 human breast cancer cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.BJP.0702103

7 January 2021

Wild-type p53 induces apoptosis of myeloid leukaemic cells that is inhibited by interleukin-6

1 reference

https://api.crossref.org/works/10.1038%2FSJ.BJP.0702103

7 January 2021

The tumor suppressor p53 is a negative regulator of estrogen receptor signaling pathways

1 reference

https://api.crossref.org/works/10.1038%2FSJ.BJP.0702103

7 January 2021

Identifiers

DOI

10.1038/SJ.BJP.0702103

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5 August 2017

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5 August 2017

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