Mechanisms of cell injury by activated oxygen species (Q35031394)

5 August 2017

2 references

12 October 2019

4 November 2019

Mechanisms of cell injury by activated oxygen species (English)

1 reference

5 August 2017

1 reference

12 October 2019

1 reference

4 November 2019

J L Farber

1

1 reference

5 August 2017

1 December 1994

3 references

5 August 2017

12 October 2019

4 November 2019

8

1 reference

Environmental Health Perspectives

inferred from page(s)

published in

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5 August 2017

12 October 2019

4 November 2019

102 Suppl 10

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5 August 2017

17-24

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Differing effects of the inhibition of poly(ADP-ribose) polymerase on the course of oxidative cell injury in hepatocytes and fibroblasts

5 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1566984

Regulation of intracellular calcium compartmentation: studies with isolated hepatocytes and t-butyl hydroperoxide

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1566984

Organic hydroperoxide-induced lipid peroxidation and cell death in isolated hepatocytes

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1566984

Liver glutathione depletion induced by bromobenzene, iodobenzene, and diethylmaleate poisoning and its relation to lipid peroxidation and necrosis.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1566984

Calcium-dependent and calcium-independent mechanisms of irreversible cell injury in cultured hepatocytes.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1566984

The pathophysiological significance of lipid peroxidation in oxidative cell injury

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1566984

Leukocytes and ischemia-induced myocardial injury

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1566984

Production of oxidative DNA damage during the metabolic activation of benzo[a]pyrene in human mammary epithelial cells correlates with cell killing

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1566984

Lipid peroxidation and mechanisms of toxicity

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1566984

Intracellular calcium homeostasis

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1566984

DNA damage and oxygen radical toxicity

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1566984

Effect of extracellular Ca++ omission on isolated hepatocytes. I. Induction of oxidative stress and cell injury.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1566984

Superoxide-dependent and -independent mechanisms of iron mobilization from ferritin by xanthine oxidase. Implications for oxygen-free-radical-induced tissue destruction during ischaemia and inflammation

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1566984

Ferric iron and superoxide ions are required for the killing of cultured hepatocytes by hydrogen peroxide. Evidence for the participation of hydroxyl radicals formed by an iron-catalyzed Haber-Weiss reaction.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1566984

Ferritin and superoxide-dependent lipid peroxidation

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1566984

Oxygen-derived free radicals in postischemic tissue injury

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1566984

Hydrogen peroxide-induced injury of cells and its prevention by inhibitors of poly(ADP-ribose) polymerase

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1566984

Oxidant injury of cells. DNA strand-breaks activate polyadenosine diphosphate-ribose polymerase and lead to depletion of nicotinamide adenine dinucleotide

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1566984

The repairability of oxidative free radical mediated damage to DNA: a review

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1566984

Oxidant-induced DNA damage of target cells

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1566984

Toxic DNA damage by hydrogen peroxide through the Fenton reaction in vivo and in vitro

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1566984

Oxidants and human disease: some new concepts

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1566984

Protease inhibitors do not prevent the killing of cultured hepatocytes by cystamine

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1566984

Metabolism of acetaminophen by cultured rat hepatocytes. Depletion of protein thiol groups without any loss of viability

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1566984

Endocytosis-independent uptake of liposome-encapsulated superoxide dismutase prevents the killing of cultured hepatocytes by tert-butyl hydroperoxide.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1566984

Liposome-encapsulated superoxide dismutase prevents liver necrosis induced by acetaminophen

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1566984

Increases in cytosolic calcium ion concentration can be dissociated from the killing of cultured hepatocytes by tert-butyl hydroperoxide.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1566984

Calcium-Mediated Mechanisms in Chemically Induced Cell Death

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1566984

Autophagic degradation of protein generates a pool of ferric iron required for the killing of cultured hepatocytes by an oxidative stress

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1566984

Biochemical mechanisms of toxic cell injury

25 October 2018

1 reference

12 December 2020

Induction and repair of DNA single-strand breaks in EM9 mutant CHO cells treated with hydrogen peroxide

1 reference

12 December 2020

Endocytosis of superoxide dismutase is required in order for the enzyme to protect hepatocytes from the cytotoxicity of hydrogen peroxide

1 reference

12 December 2020

Evidence for the participation of activated oxygen species and the resulting peroxidation of lipids in the killing of cultured hepatocytes by aryl halides

1 reference

12 December 2020

Toxic consequence of the abrupt depletion of glutathione in cultured rat hepatocytes

1 reference

12 December 2020

Peroxidation-dependent and peroxidation-independent mechanisms by which acetaminophen kills cultured rat hepatocytes

1 reference

12 December 2020

tert-butyl hydroperoxide kills cultured hepatocytes by peroxidizing membrane lipids

1 reference

12 December 2020

Mitochondrial damage as a mechanism of cell injury in the killing of cultured hepatocytes by tert-butyl hydroperoxide

1 reference

12 December 2020

Dissociation of the accumulation of single-strand breaks in DNA from the killing of cultured hepatocytes by an oxidative stress

1 reference

12 December 2020

Protein thiol depletion and the killing of cultured hepatocytes by hydrogen peroxide

1 reference

12 December 2020

Mechanisms of cell injury in the killing of cultured hepatocytes by bromobenzene

1 reference

12 December 2020

Bleb formation in hepatocytes during drug metabolism is caused by disturbances in thiol and calcium ion homeostasis

1 reference

12 December 2020

The metabolism of menadione (2-methyl-1,4-naphthoquinone) by isolated hepatocytes. A study of the implications of oxidative stress in intact cells

1 reference

12 December 2020

The role of lipid peroxidation in the toxicity of foreign compounds to liver cells

1 reference

12 December 2020

Critical role of sulfhydryl group(s) in ATP-dependent Ca2+ sequestration by the plasma membrane fraction from rat liver

1 reference

12 December 2020

In vivo formation of single-strand breaks in DNA by hydrogen peroxide is mediated by the Haber-Weiss reaction

1 reference

12 December 2020

Increase in cytosolic Ca2+ concentration during t-butyl hydroperoxide metabolism by isolated hepatocytes involves NADPH oxidation and mobilization of intracellular Ca2+ stores

1 reference

12 December 2020

Extracellular calcium protects isolated rat hepatocytes from injury

1 reference

12 December 2020

Endogenous defenses against the cytotoxicity of hydrogen peroxide in cultured rat hepatocytes

1 reference

12 December 2020

Alterations in intracellular thiol homeostasis during the metabolism of menadione by isolated rat hepatocytes

1 reference

12 December 2020

Vitamin E reversal of the effect of extracellular calcium on chemically induced toxicity in hepatocytes

1 reference

12 December 2020

Inhibition of hepatocyte plasma membrane Ca2+-ATPase activity by menadione metabolism and its restoration by thiols

1 reference

12 December 2020

Mechanism of chemical-induced toxicity. II. Role of extracellular calcium

1 reference

12 December 2020

The toxicity of acetaminophen and N-acetyl-p-benzoquinone imine in isolated hepatocytes is associated with thiol depletion and increased cytosolic Ca2+

1 reference

12 December 2020

Reductive release of iron from ferritin by cation free radicals of paraquat and other bipyridyls

1 reference

12 December 2020

Cystamine induces toxicity in hepatocytes through the elevation of cytosolic Ca2+ and the stimulation of a nonlysosomal proteolytic system

1 reference

12 December 2020

The role of acrolein in allyl alcohol-induced lipid peroxidation and liver cell damage in mice

1 reference

12 December 2020

Metabolism of pyridine nucleotides in cultured rat hepatocytes intoxicated with tert-butyl hydroperoxide

1 reference

12 December 2020

Cellular pool of transient ferric iron, chelatable by deferoxamine and distinct from ferritin, that is involved in oxidative cell injury

1 reference

12 December 2020

ATP synthase activity is required for fructose to protect cultured hepatocytes from the toxicity of cyanide

1 reference

12 December 2020

Vitamin E protection against chemical-induced cell injury. I. Maintenance of cellular protein thiols as a cytoprotective mechanism

1 reference

12 December 2020

Identifiers

DOI

10.1289/EHP.94102S1017

1 reference

5 August 2017

1 reference

5 August 2017

1 reference

PubMed ID

7705293