Emerging roles for orphan G-protein-coupled receptors in the cardiovascular system (Q35033297)

5 August 2017

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title

Emerging roles for orphan G-protein-coupled receptors in the cardiovascular system (English)

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G protein-coupled receptor

5 August 2017

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Anthony Davenport

2

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author name string

Sidath Katugampola

series ordinal

1

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PubMed ID

12498728

5 August 2017

language of work or name

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1 January 2003

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Trends in Pharmacological Sciences

5 August 2017

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5 August 2017

24

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5 August 2017

1

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5 August 2017

30-35

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Novel GPCRs and their endogenous ligands: expanding the boundaries of physiology and pharmacology

5 August 2017

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2802%2900007-X

7 January 2021

Novel neurotransmitters as natural ligands of orphan G-protein-coupled receptors

1 reference

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7 January 2021

Orphan G-protein-coupled receptors and natural ligand discovery

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https://api.crossref.org/works/10.1016%2FS0165-6147%2802%2900007-X

7 January 2021

Orphan G protein-coupled receptors in the CNS.

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2802%2900007-X

7 January 2021

[(125)I]-(Pyr(1))Apelin-13 is a novel radioligand for localizing the APJ orphan receptor in human and rat tissues with evidence for a vasoconstrictor role in man

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2802%2900007-X

7 January 2021

[125I-His(9)]-ghrelin, a novel radioligand for localizing GHS orphan receptors in human and rat tissue: up-regulation of receptors with athersclerosis

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2802%2900007-X

7 January 2021

Discovery of recently adopted orphan receptors for apelin, urotensin II, and ghrelin identified using novel radioligands and functional role in the human cardiovascular system.

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2802%2900007-X

7 January 2021

Characterization of apelin, the ligand for the APJ receptor

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2802%2900007-X

7 January 2021

Identification and characterization of two neuromedin U receptors differentially expressed in peripheral tissues and the central nervous system

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2802%2900007-X

7 January 2021

Nociceptin receptor activation produces nitric oxide-mediated systemic hypotension

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2802%2900007-X

7 January 2021

Pressor effects of orexins injected intracisternally and to rostral ventrolateral medulla of anesthetized rats

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2802%2900007-X

7 January 2021

Human urotensin-II is a potent vasoconstrictor and agonist for the orphan receptor GPR14

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2802%2900007-X

7 January 2021

Pharmacological characterization and tissue distribution of the human and rat GALR1 receptors

1 reference

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7 January 2021

Discovery of a receptor related to the galanin receptors

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2802%2900007-X

7 January 2021

Metastasis suppressor gene KiSS-1 encodes peptide ligand of a G-protein-coupled receptor

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2802%2900007-X

7 January 2021

Proteomics in drug discovery

1 reference

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7 January 2021

Epigenesis: the missing beat in biotechnology?

1 reference

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7 January 2021

Proenkephalin A gene products activate a new family of sensory neuron--specific GPCRs

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2802%2900007-X

7 January 2021

Isolation and characterization of a novel endogenous peptide ligand for the human APJ receptor

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2802%2900007-X

7 January 2021

Orphan-receptor ligand human urotensin II: receptor localization in human tissues and comparison of vasoconstrictor responses with endothelin-1

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2802%2900007-X

7 January 2021

Endocrinology. This hormone has been relaxin' too long!

1 reference

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7 January 2021

Quantitative autoradiographic studies of relaxin binding in rat atria, uterus and cerebral cortex: characterization and effects of oestrogen treatment

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2802%2900007-X

7 January 2021

Is urotensin-II the new endothelin?

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2802%2900007-X

7 January 2021

Identification of nonpeptidic urotensin II receptor antagonists by virtual screening based on a pharmacophore model derived from structure-activity relationships and nuclear magnetic resonance studies on urotensin II.

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2802%2900007-X

7 January 2021

Ghrelin is a growth-hormone-releasing acylated peptide from stomach

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2802%2900007-X

7 January 2021

Neuroendocrine and peripheral activities of ghrelin: implications in metabolism and obesity

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2802%2900007-X

7 January 2021

Comparison of vasodilators in human internal mammary artery: ghrelin is a potent physiological antagonist of endothelin-1.

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2802%2900007-X

7 January 2021

Narcolepsy in orexin knockout mice: molecular genetics of sleep regulation

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2802%2900007-X

7 January 2021

Orphanin FQ: a neuropeptide that activates an opioidlike G protein-coupled receptor.

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2802%2900007-X

7 January 2021

Orexins and orexin receptors: a family of hypothalamic neuropeptides and G protein-coupled receptors that regulate feeding behavior

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2802%2900007-X

7 January 2021

A prolactin-releasing peptide in the brain

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2802%2900007-X

7 January 2021

Melanin-concentrating hormone is the cognate ligand for the orphan G-protein-coupled receptor SLC-1

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2802%2900007-X

7 January 2021

Receptor for motilin identified in the human gastrointestinal system

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2802%2900007-X

7 January 2021

TIP39: a new neuropeptide and PTH2-receptor agonist from hypothalamus

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2802%2900007-X

7 January 2021

Identification of receptors for neuromedin U and its role in feeding

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2802%2900007-X

7 January 2021

Identification and characterization of a melanin-concentrating hormone receptor

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2802%2900007-X

7 January 2021

Identification of urocortin III, an additional member of the corticotropin-releasing factor (CRF) family with high affinity for the CRF2 receptor

1 reference

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7 January 2021

Activation of orphan receptors by the hormone relaxin

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2802%2900007-X

7 January 2021

Molecular and functional characteristics of APJ. Tissue distribution of mRNA and interaction with the endogenous ligand apelin

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2802%2900007-X

7 January 2021

Characterization and distribution of prolactin releasing peptide (PrRP) binding sites in the rat--evidence for a novel binding site subtype in cardiac and skeletal muscle.

1 reference

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7 January 2021

Molecular cloning and functional characterization of MCH2, a novel human MCH receptor

1 reference

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7 January 2021

Studies of the cardiovascular effects of nociceptin and related peptides

1 reference

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7 January 2021

Orexin-A in the human brain and tumor tissues of ganglioneuroblastoma and neuroblastoma

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2802%2900007-X

7 January 2021

Melanin-concentrating hormone in human and rat

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2802%2900007-X

7 January 2021

Release of motilin by oral and intravenous nutrients in man

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2802%2900007-X

7 January 2021

Role of urotensin II in patients on dialysis

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2802%2900007-X

7 January 2021

Nociceptin activation of the human ORL1 receptor expressed in Chinese hamster ovary cells: functional homology with opioid receptors

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2802%2900007-X

7 January 2021

Characterization of the binding of [(125)I]-human prolactin releasing peptide (PrRP) to GPR10, a novel G protein coupled receptor

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2802%2900007-X

7 January 2021

Motilin receptors in the human antrum

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2802%2900007-X

7 January 2021

125I-Antisauvagine-30: a novel and specific high-affinity radioligand for the characterization of corticotropin-releasing factor type 2 receptors

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2802%2900007-X

7 January 2021

Species differences in the efficacy of compounds at the nociceptin receptor (ORL1)

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2802%2900007-X

7 January 2021

The hypocretins are weak agonists at recombinant human orexin-1 and orexin-2 receptors

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2802%2900007-X

7 January 2021

Contractile effects and intracellular Ca2+ signalling induced by motilin and erythromycin in the circular smooth muscle of human colon

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2802%2900007-X

7 January 2021

The metastasis suppressor gene KiSS-1 encodes kisspeptins, the natural ligands of the orphan G protein-coupled receptor GPR54

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2802%2900007-X

7 January 2021

Human stresscopin and stresscopin-related peptide are selective ligands for the type 2 corticotropin-releasing hormone receptor

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2802%2900007-X

7 January 2021

10.1016/S0165-6147(02)00007-X

Identifiers

DOI

1 reference

5 August 2017

1 reference

PubMed ID

12498728