Mechanisms of estrogens' dose-dependent neuroprotective and neurodamaging effects in experimental models of cerebral ischemia. (Q35036040)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21673906%20AND%20SRC:MED&resulttype=core&format=json

4 February 2020

review article

2 references

26 January 2021

Mechanisms of estrogens' dose-dependent neuroprotective and neurodamaging effects in experimental models of cerebral ischemia (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21673906%20AND%20SRC:MED&resulttype=core&format=json

4 February 2020

4 references

22 March 2019

25 April 2019

17 June 2019

17 November 2019

1 reference

17 November 2019

1 reference

neuroprotective agent

1 reference

26 January 2021

1

1 reference

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4 February 2020

3

Elvar Theodorsson

1 reference

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4 February 2020

author name string

Annette Theodorsson

series ordinal

2

1 reference

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language of work or name

English

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publication date

25 February 2011

6 references

22 March 2019

25 April 2019

17 June 2019

17 November 2019

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4 February 2020

26 January 2021

International Journal of Molecular Sciences

5 references

22 March 2019

25 April 2019

17 June 2019

17 November 2019

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4 February 2020

volume

12

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4 February 2020

issue

3

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4 February 2020

page(s)

1533-1562

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Creative Commons Attribution 3.0 Unported

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copyright license

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25 April 2019

17 June 2019

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on focus list of Wikimedia project

26 January 2021

copyright status

copyrighted

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Different methods for administering 17beta-estradiol to ovariectomized rats result in opposite effects on ischemic brain damage

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Oestradiol and insulin-like growth factor-1 reduce cell loss after global ischaemia in middle-aged female rats

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The risk of stroke in postmenopausal women receiving hormonal therapy

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8 July 2018

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8 July 2018

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Neuroprotection by estrogen in the brain: the mitochondrial compartment as presumed therapeutic target

8 July 2018

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The complexity of neurobiological processes in acute ischemic stroke

8 July 2018

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Estradiol rescues neurons from global ischemia-induced cell death: multiple cellular pathways of neuroprotection

8 July 2018

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Role of protein phosphatases and mitochondria in the neuroprotective effects of estrogens

8 July 2018

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Estradiol is a potent protective, restorative, and trophic factor after brain injury.

8 July 2018

1 reference

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Neuroprotective effects of estrogens following ischemic stroke.

8 July 2018

1 reference

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Apoptotic mechanisms after cerebral ischemia

8 July 2018

1 reference

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Effects of 17beta-estradiol, and its metabolite, 4-hydroxyestradiol on fertilization, embryo development and oxidative DNA damage in sand dollar (Dendraster excentricus) sperm

8 July 2018

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Tamoxifen mediated estrogen receptor activation protects against early impairment of hippocampal neuron excitability in an oxygen/glucose deprivation brain slice ischemia model

8 July 2018

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Vascular endothelial growth factor and angiopoietins in neurovascular regeneration and protection following stroke.

8 July 2018

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Estrogen affects levels of Bcl-2 protein and mRNA in medial amygdala of ovariectomized rats

8 July 2018

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More than a decade of estrogen neuroprotection.

8 July 2018

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Estrogen anti-inflammatory activity in brain: a therapeutic opportunity for menopause and neurodegenerative diseases

8 July 2018

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Methoxychlor and estradiol induce oxidative stress DNA damage in the mouse ovarian surface epithelium

8 July 2018

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Mitochondrial superoxide dismutase activation with 17 beta-estradiol-treated human lens epithelial cells.

8 July 2018

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Long-term administration of estrogen or tamoxifen to ovariectomized rats affords neuroprotection to hippocampal neurons by modulating the expression of Bcl-2 and Bax.

8 July 2018

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Effects of estrogen receptor agonists on regulation of the inflammatory response in astrocytes from young adult and middle-aged female rats.

8 July 2018

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Progesterone and estrogen regulate oxidative metabolism in brain mitochondria

8 July 2018

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Inducible nitric oxide synthase and estradiol exhibit complementary neuroprotective roles after ischemic brain injury

8 July 2018

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Mechanistic investigations on the antioxidant action of a neuroprotective estrogen derivative

8 July 2018

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Evidence to implicate early modulation of interleukin-1beta expression in the neuroprotection afforded by 17beta-estradiol in male rats undergone transient middle cerebral artery occlusion

8 July 2018

1 reference

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Effects of estrogen against LPS-induced inflammation and toxicity in primary rat glial and neuronal cultures

8 July 2018

1 reference

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Role of signal transducer and activator of transcription-3 in estradiol-mediated neuroprotection

8 July 2018

1 reference

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Cerebrovascular effects of oestrogen: multiplicity of action

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3111617

Timing of estrogen therapy after ovariectomy dictates the efficacy of its neuroprotective and antiinflammatory actions.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3111617

Structure-nongenomic neuroprotection relationship of estrogens and estrogen-derived compounds

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3111617

Acute pretreatment with estradiol protects against CA1 cell loss and spatial learning impairments resulting from transient global ischemia

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3111617

Age alters cerebrovascular inflammation and effects of estrogen

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3111617

MAPK signaling is critical to estradiol protection of CA1 neurons in global ischemia

8 July 2018

1 reference

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Cross-talk between IGF-I and estradiol in the brain: focus on neuroprotection

8 July 2018

1 reference

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Influence of sex steroid hormones on cerebrovascular function

8 July 2018

1 reference

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Gender differences in neurological disease: role of estrogens and cytokines

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3111617

G protein-coupled receptor 30 is an estrogen receptor in the plasma membrane

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3111617

Neuroprotective effects of 17beta-estradiol and nonfeminizing estrogens against H2O2 toxicity in human neuroblastoma SK-N-SH cells

8 July 2018

1 reference

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17Beta-estradiol protects against oxidative stress-induced cell death through the glutathione/glutaredoxin-dependent redox regulation of Akt in myocardiac H9c2 cells

8 July 2018

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Functional estrogen receptors in the mitochondria of breast cancer cells

8 July 2018

1 reference

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Estrogen's effects on central and circulating immune cells vary with reproductive age.

8 July 2018

1 reference

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Neuroprotective effect of an antioxidant in ischemic brain injury: involvement of neuronal apoptosis

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3111617

Acute and chronic estradiol treatments reduce memory deficits induced by transient global ischemia in female rats

8 July 2018

1 reference

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Estrogen-induced mitochondrial reactive oxygen species as signal-transducing messengers.

8 July 2018

1 reference

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Lack of oestrogen protection in amyloid-mediated endothelial damage due to protein nitrotyrosination

8 July 2018

1 reference

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Astrocyte-derived transforming growth factor-{beta} mediates the neuroprotective effects of 17{beta}-estradiol: involvement of nonclassical genomic signaling pathways

8 July 2018

1 reference

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Glutamate-induced apoptosis in primary cortical neurons is inhibited by equine estrogens via down-regulation of caspase-3 and prevention of mitochondrial cytochrome c release

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3111617

Apoptosis in cerebral ischemia: executional and regulatory signaling mechanisms

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3111617

Mitochondria play a central role in estrogen-induced neuroprotection.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3111617

Effects of combined estrogen and progesterone on brain infarction in reproductively senescent female rats

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3111617

17 Beta-estradiol prevents focal cerebral ischemic damages via activation of Akt and CREB in association with reduced PTEN phosphorylation in rats

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3111617

Suppression by 17beta-estradiol of monocyte adhesion to vascular endothelial cells is mediated by estrogen receptors

8 July 2018

1 reference

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Differential effects of 17beta-estradiol upon stroke damage in stroke prone and normotensive rats

8 July 2018

1 reference

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Nitric oxide, oxidants, and protein tyrosine nitration

8 July 2018

1 reference

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Quinol-based cyclic antioxidant mechanism in estrogen neuroprotection

8 July 2018

1 reference

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Differential effects of estrogen in the injured forebrain of young adult and reproductive senescent animals.

8 July 2018

1 reference

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Estrogen receptor-alpha mediates the brain antiinflammatory activity of estradiol

8 July 2018

1 reference

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Modulation of antioxidant enzyme expression and function by estrogen

8 July 2018

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Hormesis: the dose-response revolution

8 July 2018

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Risks and benefits of estrogen plus progestin in healthy postmenopausal women: principal results From the Women's Health Initiative randomized controlled trial

8 July 2018

1 reference

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Cerebral thrombosis and microcirculation of the rat during the oestrous cycle and after ovariectomy.

8 July 2018

1 reference

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Differential effects of glucocorticoids and gonadal steroids on glutathione levels in neuronal and glial cell systems

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3111617

17beta-estradiol increases rat cerebrovascular prostacyclin synthesis by elevating cyclooxygenase-1 and prostacyclin synthase

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3111617

17beta-Estradiol reduces cortical lesion size in the glutamate excitotoxicity model by enhancing extracellular lactate: a new neuroprotective pathway

8 July 2018

1 reference

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Estrogens decrease reperfusion-associated cortical ischemic damage: an MRI analysis in a transient focal ischemia model

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3111617

Postischemic estrogen reduces hypoperfusion and secondary ischemia after experimental stroke

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3111617

Estrogen decreases infarct size after temporary focal ischemia in a genetic model of type 1 diabetes mellitus

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3111617

Neuroprotection by estradiol.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3111617

Regulation of vascular endothelial growth factor (VEGF) gene transcription by estrogen receptors alpha and beta

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3111617

Estradiol protects against ischemic brain injury in middle-aged rats

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3111617

Acute effects of estradiol and of diethylstilbestrol: pro- or antioxidant potential?

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3111617

Gonadal hormones affect diameter of male rat cerebral arteries through endothelium-dependent mechanisms

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3111617

Estrogen reduces mouse cerebral artery tone through endothelial NOS- and cyclooxygenase-dependent mechanisms

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3111617

Neuroprotective effects of female gonadal steroids in reproductively senescent female rats

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3111617

Estradiol inhibits leukocyte adhesion and transendothelial migration in rabbits in vivo : possible mechanisms for gender differences in atherosclerosis

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3111617

Estrogen decreases TNF gene expression by blocking JNK activity and the resulting production of c-Jun and JunD.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3111617

17beta-estradiol reduces stroke injury in estrogen-deficient female animals

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3111617

Role of apolipoprotein E and estrogen in mossy fiber sprouting in hippocampal slice cultures

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3111617

Estrogen hormones reduce lipid peroxidation in cells and tissues of the central nervous system

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3111617

Estrogen modulates neuronal Bcl-xL expression and beta-amyloid-induced apoptosis: relevance to Alzheimer's disease.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3111617

Estradiol increases spine density and NMDA-dependent Ca2+ transients in spines of CA1 pyramidal neurons from hippocampal slices

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3111617

Estrogen provides neuroprotection in transient forebrain ischemia through perfusion-independent mechanisms in rats

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3111617

17beta-estradiol enhances NMDA receptor-mediated EPSPs and long-term potentiation

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3111617

Modulation of Bcl-2 expression: a potential component of estrogen protection in NT2 neurons

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3111617

Estrogen regulates myogenic tone in pressurized cerebral arteries by enhanced basal release of nitric oxide.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3111617

17beta-Estradiol protects against NMDA-induced excitotoxicity by direct inhibition of NMDA receptors

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3111617

Repression of interleukin-6 gene expression by 17 beta-estradiol: inhibition of the DNA-binding activity of the transcription factors NF-IL6 and NF-kappa B by the estrogen receptor

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3111617

Neuroprotection against oxidative stress by estrogens: structure-activity relationship

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3111617

Antagonism between estradiol and progestin on Bcl-2 expression in breast-cancer cells

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3111617

LTP varies across the estrous cycle: enhanced synaptic plasticity in proestrus rats.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3111617

Peripheral administration of Interleukin-1 Receptor antagonist inhibits brain damage after focal cerebral ischemia in the rat.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3111617

Gonadal steroids as promoting factors in axonal regeneration

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3111617

Altered gene expression in neurons during programmed cell death: identification of c-jun as necessary for neuronal apoptosis

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3111617

Estrogen promotes chemotherapeutic drug resistance by a mechanism involving Bcl-2 proto-oncogene expression in human breast cancer cells

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3111617

17-beta estradiol protects neurons from oxidative stress-induced cell death in vitro

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3111617

Identification of a putative estrogen response element in the gene encoding brain-derived neurotrophic factor.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3111617

Sex steroid effects on extrahypothalamic CNS. I. Estrogen augments neuronal responsiveness to iontophoretically applied glutamate in the cerebellum.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3111617

Lesions to Schaffer collaterals prevent ischemic death of CA1 pyramidal cells

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3111617

Ischemic CA-1 pyramidal cell loss is prevented by preischemic colchicine destruction of dentate gyrus granule cells

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3111617

Evidence for amelioration of ischaemic neuronal damage in the hippocampal formation by lesions of the perforant path

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3111617

Sex differences in postischemic neuronal necrosis in gerbils

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3111617

Estrogen-enhanced neurite growth: evidence for a selective induction of Tau and stable microtubules

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3111617

Estradiol mediates fluctuation in hippocampal synapse density during the estrous cycle in the adult rat.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3111617

Estradiol selectively regulates agonist binding sites on the N-methyl-D-aspartate receptor complex in the CA1 region of the hippocampus

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3111617

Estrogens may reduce mortality and ischemic damage caused by middle cerebral artery occlusion in the female rat.

8 July 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJMS12031533

Deleterious effect of beta-estradiol in a rat model of transient forebrain ischemia

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJMS12031533

17beta-estradiol potentiates ischemia-reperfusion injury in diabetic ovariectomized female rats

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJMS12031533

Estradiol increases brain lesions in the cortex and lateral striatum after transient occlusion of the middle cerebral artery in rats: no effect of ischemia on galanin in the stroke area but decreased levels in the hippocampus

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJMS12031533

Effects of 17beta-oestradiol on cerebral ischaemic damage and lipid peroxidation

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJMS12031533

Detrimental effects of 17beta-oestradiol after permanent middle cerebral artery occlusion

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJMS12031533

Order of magnitude differences between methods for maintaining physiological 17beta-oestradiol concentrations in ovariectomized rats

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJMS12031533

High-soy diet decreases infarct size after permanent middle cerebral artery occlusion in female rats

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJMS12031533

Proestrus levels of estradiol during transient global cerebral ischemia improves the histological outcome of the hippocampal CA1 region: perfusion-dependent and-independent mechanisms

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJMS12031533

Cerebral vasodilating capacity during forebrain ischemia: effects of chronic estrogen depletion and repletion and the role of neuronal nitric oxide synthase

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJMS12031533

Estrogen attenuates neuronal excitability in the insular cortex following middle cerebral artery occlusion.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJMS12031533

Chronic 17beta-estradiol pretreatment and ischemia-induced hippocampal degeneration and memory impairments: a 6-month survival study.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJMS12031533

Effects of combined oral conjugated estrogens and medroxyprogesterone acetate on brain infarction size after experimental stroke in rat.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJMS12031533

Substantial discrepancies in 17beta-oestradiol concentrations obtained with three different commercial direct radioimmunoassay kits in rat sera

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJMS12031533

Estradiol enhances neurogenesis following ischemic stroke through estrogen receptors alpha and beta

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJMS12031533

Estrogen protects primary cortical neurons from glutamate toxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJMS12031533

Oestrogen and stroke: the potential for harm as well as benefit

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJMS12031533

Comparable attenuation of Abeta(25-35)-induced neurotoxicity by quercitrin and 17beta-estradiol in cultured rat hippocampal neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJMS12031533

Neuroprotective and neurotoxic effects of estrogens

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJMS12031533

Multiple effects of 2ME2 and D609 on the cortical expression of HIF-1alpha and apoptotic genes in a middle cerebral artery occlusion-induced focal ischemia rat model

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJMS12031533

Downregulation of glutaredoxin but not glutathione loss leads to mitochondrial dysfunction in female mice CNS: implications in excitotoxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJMS12031533

Down-regulation of glutaredoxin by estrogen receptor antagonist renders female mice susceptible to excitatory amino acid mediated complex I inhibition in CNS.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJMS12031533

17Beta-estradiol reduces nitrotyrosine immunoreactivity and increases SOD1 and SOD2 immunoreactivity in nigral neurons in male mice following MPTP insult

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJMS12031533

Estradiol in vivo regulation of brain mitochondrial proteome.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJMS12031533

Effect of gender on NADPH-oxidase activity, expression, and function in the cerebral circulation: role of estrogen.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJMS12031533

4-hydroxyestradiol induces anchorage-independent growth of human mammary epithelial cells via activation of IkappaB kinase: potential role of reactive oxygen species

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJMS12031533

Tumor necrosis factor-alpha. A mediator of focal ischemic brain injury

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJMS12031533

Delayed administration of interleukin-1 receptor antagonist protects against transient cerebral ischaemia in the rat.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJMS12031533

Neuroprotective effects of human recombinant interleukin-1 receptor antagonist in focal cerebral ischaemia in the rat.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJMS12031533

Estrogen suppresses IL-1beta-mediated induction of COX-2 pathway in rat cerebral blood vessels

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJMS12031533

Inflammation and epithelial alterations in rat prostate: impact of the androgen to oestrogen ratio.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJMS12031533

Estrogen attenuates nuclear factor-kappa B activation induced by transient cerebral ischemia

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJMS12031533

Effects of estrogen and raloxifene on neuroglia number and morphology in the hippocampus of aged female mice

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJMS12031533

Inducible nitric oxide synthase contributes to gender differences in ischemic brain injury

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJMS12031533

Estrogen replacement treatment in diabetic ovariectomized female rats potentiates postischemic leukocyte adhesion in cerebral venules

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJMS12031533

Estradiol is required for a proper immune response to bacterial and viral pathogens in the female brain

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJMS12031533

Estradiol reduces activity of the blood-brain barrier Na-K-Cl cotransporter and decreases edema formation in permanent middle cerebral artery occlusion

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJMS12031533

Estrogens inhibit l-glutamate uptake activity of astrocytes via membrane estrogen receptor alpha

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJMS12031533

Neuroprotective properties of propofol and midazolam, but not pentobarbital, on neuronal damage induced by forebrain ischemia, based on the GABAA receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJMS12031533

17 beta-estradiol treatment retards excitotoxic delayed degeneration in substantia nigra reticulata neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJMS12031533

17beta-estradiol effect on the extracellular concentration of amino acids in the glutamate excitotoxicity model in the rat.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJMS12031533

Acute effects of 17beta-estradiol on the extracellular concentration of excitatory amino acids and energy metabolites during transient cerebral ischemia in male rats

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJMS12031533

Amelioration of hippocampal neuronal damage after global ischemia by neuronal overexpression of BCL-2 in transgenic mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJMS12031533

Estrogen-induced Bcl-2 expression after spinal cord injury is mediated through phosphoinositide-3-kinase/Akt-dependent CREB activation

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJMS12031533

Nongenomic antiapoptotic signal transduction by estrogen in cultured cortical neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJMS12031533

Gonadal hormone regulation of insulin-like growth factor-I-like immunoreactivity in hypothalamic astroglia of developing and adult rats.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJMS12031533

Region- and peptide-specific regulation of the neurotrophins by estrogen

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJMS12031533

Estrogen receptor alpha forms estrogen-dependent multimolecular complexes with insulin-like growth factor receptor and phosphatidylinositol 3-kinase in the adult rat brain

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJMS12031533

Estrogen interacts with the IGF-1 system to protect nigrostriatal dopamine and maintain motoric behavior after 6-hydroxdopamine lesions

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJMS12031533

Estrogen modulates the growth-associated protein GAP-43 (Neuromodulin) mRNA in the rat preoptic area and basal hypothalamus

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJMS12031533

Estrogen regulates neurofilament gene expression in adult female rat dorsal root ganglion neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJMS12031533

Relaxant effects of 17-beta-estradiol in cerebral arteries through Ca(2+) entry inhibition

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJMS12031533

17beta-estradiol decreases vascular tone in cerebral arteries by shifting COX-dependent vasoconstriction to vasodilation

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJMS12031533

Estrogen-Induced Augmentation of Endothelium-Dependent Nitric Oxide-Mediated Vasodilation in Isolated Rat Cerebral Small Arteries

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJMS12031533

Chronic estrogen treatment increases levels of endothelial nitric oxide synthase protein in rat cerebral microvessels

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJMS12031533

Nitric-oxide-dependent pial arteriolar dilation in the female rat: effects of chronic estrogen depletion and repletion.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJMS12031533

17 Beta-estradiol increases endothelial nitric oxide synthase mRNA copy number in cerebral blood vessels: quantification by real-time polymerase chain reaction

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJMS12031533

Effect of short-term phytoestrogen treatment in male rats on nitric oxide-mediated responses of carotid and cerebral arteries: comparison with 17beta-estradiol

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJMS12031533

Gender-linked brain injury in experimental stroke

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJMS12031533

Oscillations of cerebrovascular resistance throughout the menstrual cycle in healthy women.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJMS12031533

Investigation of estrogen status and increased stroke sensitivity on cerebral blood flow after a focal ischemic insult.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJMS12031533

Estradiol increases pre- and post-synaptic proteins in the CA1 region of the hippocampus in female rhesus macaques (Macaca mulatta).

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJMS12031533

Neuroprotection by Estrogens in a Mouse Model of Focal Cerebral Ischemia and in Cultured Neurons: Evidence for a Receptor-Independent Antioxidative Mechanism

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJMS12031533

The effects of 17beta estradiol, 17alpha estradiol and progesterone on oxidative stress biomarkers in ovariectomized female rat brain subjected to global cerebral ischemia.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3111617

Acute effects of 17beta-estradiol on oxidative stress in ischemic rat striatum.

25 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3111617

Estradiol attenuates programmed cell death after stroke-like injury.

25 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3111617

Estradiol differentially regulates c-Fos after focal cerebral ischemia.

25 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3111617

The effect of ovarian hormones on antioxidant enzyme activities in the brain of male rats.

25 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3111617

17beta-estradiol activates ICI 182,780-sensitive estrogen receptors and cyclic GMP-dependent thioredoxin expression for neuroprotection

25 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3111617

Long-term estrogen therapy worsens the behavioral and neuropathological consequences of chronic brain inflammation

25 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3111617

Estrogen protects against global ischemia-induced neuronal death and prevents activation of apoptotic signaling cascades in the hippocampal CA1.

25 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3111617

Selected contribution: cerebrovascular nos and cyclooxygenase are unaffected by estrogen in mice lacking estrogen receptor-alpha.

25 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3111617

Estrogen restores postischemic pial microvascular dilation

25 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3111617

Estrogen prevents the lipopolysaccharide-induced inflammatory response in microglia.

25 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3111617

Neuroprotective effects of estradiol in middle-aged female rats

25 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3111617

Estrogen-induced activation of the mitogen-activated protein kinase cascade in the cerebral cortex of estrogen receptor-alpha knock-out mice.

25 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3111617

Estradiol modulates bcl-2 in cerebral ischemia: a potential role for estrogen receptors

25 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3111617

Estrogen and NGF synergistically protect terminally differentiated, ERalpha-transfected PC12 cells from apoptosis

25 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3111617

Estrogen reduces myogenic tone through a nitric oxide-dependent mechanism in rat cerebral arteries.

25 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3111617

Mechanisms involved in the protective effect of estradiol-17beta on lipid peroxidation and DNA damage.

25 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3111617

Aggregated amyloid-beta protein induces cortical neuronal apoptosis and concomitant "apoptotic" pattern of gene induction.

25 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3111617

Upregulation of bax protein levels in neurons following cerebral ischemia.

25 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3111617

Inhibition of tumor necrosis factor and amelioration of brain infarction in mice

25 October 2018

1 reference

12 December 2020

17Beta-estradiol attenuates oxidative impairment of synaptic Na+/K+-ATPase activity, glucose transport, and glutamate transport induced by amyloid beta-peptide and iron

1 reference

12 December 2020

Long-term neuroprotection by benzodiazepine full versus partial agonists after transient cerebral ischemia in the gerbil [corrected]

1 reference

12 December 2020

Roles of estradiol and progesterone in regulation of hippocampal dendritic spine density during the estrous cycle in the rat

1 reference

12 December 2020

Steroid hormone effects on NMDA receptor binding and NMDA receptor mRNA levels in the hypothalamus and cerebral cortex of the adult rat

1 reference

12 December 2020

Requirement of reactive oxygen species generation in apoptosis of leukemia cells induced by 2-methoxyestradiol

1 reference

12 December 2020

Treatment with estrogen and progesterone affects relative levels of brain-derived neurotrophic factor mRNA and protein in different regions of the adult rat brain

1 reference

12 December 2020

Neuroprotective effects of estradiol in the adult rat hippocampus: Interaction with insulin-like growth factor-I signalling

1 reference

12 December 2020

Therapeutic neutralization of CD95-ligand and TNF attenuates brain damage in stroke

1 reference

12 December 2020

Estrogen and Bcl-2: gene induction and effect of transgene in experimental stroke

1 reference

12 December 2020

Gonadal steroids: effects on excitability of hippocampal pyramidal cells

1 reference

12 December 2020

Estradiol replacement to female rats facilitates dorsal hippocampal but not ventral hippocampal kindled seizure acquisition

1 reference

12 December 2020

Interleukin-1 as a pathogenetic mediator of ischemic brain damage in rats

1 reference

12 December 2020

Postischemic cerebral blood flow recovery in the female: effect of 17 beta-estradiol

1 reference

12 December 2020

17 beta-Estradiol potentiates kainate-induced currents via activation of the cAMP cascade

1 reference

12 December 2020

Estrogens attenuate and corticosterone exacerbates excitotoxicity, oxidative injury, and amyloid beta-peptide toxicity in hippocampal neurons

1 reference

12 December 2020

Estrogen induction of TGF-alpha is mediated by an estrogen response element composed of two imperfect palindromes

1 reference

12 December 2020

Estradiol increases the sensitivity of hippocampal CA1 pyramidal cells to NMDA receptor-mediated synaptic input: correlation with dendritic spine density

1 reference

12 December 2020

Estrogen protects neuronal cells from the cytotoxicity induced by acetylcholinesterase-amyloid complexes

1 reference

12 December 2020

Mediation of the immunomodulatory effect of beta-estradiol on inflammatory responses by inhibition of recruitment and activation of inflammatory cells and their gene expression of TNF-alpha and IFN-gamma

1 reference

12 December 2020

Gonadal hormones affect neuronal vulnerability to excitotoxin-induced degeneration

1 reference

12 December 2020

Effects of estrogen on leukocyte adhesion after transient forebrain ischemia

1 reference

12 December 2020

Antiinflammatory effects of estrogen on microglial activation

1 reference

12 December 2020

Identifiers

DOI

10.3390/IJMS12031533

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21673906%20AND%20SRC:MED&resulttype=core&format=json

4 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21673906%20AND%20SRC:MED&resulttype=core&format=json

4 February 2020

PubMed publication ID

21673906

1 reference