EGFR signaling suppresses osteoblast differentiation and inhibits expression of master osteoblastic transcription factors Runx2 and Osterix. (Q35036375)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21381079%20AND%20SRC:MED&resulttype=core&format=json

24 January 2020

title

EGFR signaling suppresses osteoblast differentiation and inhibits expression of master osteoblastic transcription factors Runx2 and Osterix (English)

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24 January 2020

0 references

4

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24 January 2020

author name string

Ji Zhu

1

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24 January 2020

Emi Shimizu

2

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24 January 2020

Xianrong Zhang

3

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24 January 2020

Ling Qin

5

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24 January 2020

publication date

1 July 2011

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Journal of Cellular Biochemistry

24 January 2020

published in

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24 January 2020

volume

112

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24 January 2020

page(s)

1749-1760

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24 January 2020

issue

7

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Epidermal growth factor receptor plays an anabolic role in bone metabolism in vivo

24 January 2020

cites work

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Betacellulin inhibits osteogenic differentiation and stimulates proliferation through HIF-1alpha

8 July 2018

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Parathyroid hormone stimulates osteoblastic expression of MCP-1 to recruit and increase the fusion of pre/osteoclasts

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Transcriptional regulation of the osterix (Osx, Sp7) promoter by tumor necrosis factor identifies disparate effects of mitogen-activated protein kinase and NF kappa B pathways

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Runx2: a master organizer of gene transcription in developing and maturing osteoblasts

8 July 2018

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8 July 2018

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8 July 2018

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MCP-1 is induced by receptor activator of nuclear factor-{kappa}B ligand, promotes human osteoclast fusion, and rescues granulocyte macrophage colony-stimulating factor suppression of osteoclast formation

8 July 2018

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Amphiregulin is a novel growth factor involved in normal bone development and in the cellular response to parathyroid hormone stimulation

8 July 2018

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Histone deacetylase 3 interacts with runx2 to repress the osteocalcin promoter and regulate osteoblast differentiation

8 July 2018

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Autoregulation of bone sialoprotein gene in pre-osteoblastic and non-osteoblastic cells

8 July 2018

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Activation of p38 Mitogen-Activated Protein Kinase Is Required for Osteoblast Differentiation

8 July 2018

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Runx2 (Cbfa1, AML-3) interacts with histone deacetylase 6 and represses the p21(CIP1/WAF1) promoter

8 July 2018

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Identification of novel protein/DNA interactions within the promoter of the bone-related transcription factor Runx2/Cbfa1.

8 July 2018

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The novel zinc finger-containing transcription factor osterix is required for osteoblast differentiation and bone formation

8 July 2018

1 reference

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Bone morphogenetic proteins, extracellular matrix, and mitogen-activated protein kinase signaling pathways are required for osteoblast-specific gene expression and differentiation in MC3T3-E1 cells

8 July 2018

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The EGFR family and its ligands in human cancer. signalling mechanisms and therapeutic opportunities

8 July 2018

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Erk is essential for growth, differentiation, integrin expression, and cell function in human osteoblastic cells

8 July 2018

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Molecular mechanisms underlying ErbB2/HER2 action in breast cancer

8 July 2018

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Histone deacetylases: silencers for hire.

8 July 2018

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Cbfa1 isoforms exert functional differences in osteoblast differentiation

8 July 2018

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Osteoclast differentiation factor is a ligand for osteoprotegerin/osteoclastogenesis-inhibitory factor and is identical to TRANCE/RANKL

8 July 2018

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Cbfa1, a candidate gene for cleidocranial dysplasia syndrome, is essential for osteoblast differentiation and bone development

8 July 2018

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Targeted disruption of Cbfa1 results in a complete lack of bone formation owing to maturational arrest of osteoblasts

8 July 2018

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8 July 2018

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8 July 2018

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Two distinct osteoblast-specific cis-acting elements control expression of a mouse osteocalcin gene

8 July 2018

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8 July 2018

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8 July 2018

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8 July 2018

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Epidermal growth factor-induced rapid retinoblastoma phosphorylation at Ser780 and Ser795 is mediated by ERK1/2 in small intestine epithelial cells

8 July 2018

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Histone deacetylase 1-mediated histone modification regulates osteoblast differentiation.

21 January 2018

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21 January 2018

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The retinoblastoma protein acts as a transcriptional coactivator required for osteogenic differentiation

21 January 2018

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12 December 2020

EGF Receptor Expression in Mineralized Tissues: AnIn SituHybridization and Immunocytochemical Investigation in Rat and Human Mandibles

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12 December 2020

Study of osteoblast-specific expression of one mouse osteocalcin gene: characterization of the factor binding to OSE2

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12 December 2020

MCP-1-induced human osteoclast-like cells are tartrate-resistant acid phosphatase, NFATc1, and calcitonin receptor-positive but require receptor activator of NFkappaB ligand for bone resorption

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12 December 2020

EGF-like ligands stimulate osteoclastogenesis by regulating expression of osteoclast regulatory factors by osteoblasts: implications for osteolytic bone metastases

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12 December 2020

Identifiers

DOI

10.1002/JCB.23094

1 reference

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24 January 2020

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24 January 2020

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