Toll-like receptor 3 is a potent negative regulator of axonal growth in mammals (Q35037100)

5 August 2017

title

Toll-like receptor 3 is a potent negative regulator of axonal growth in mammals (English)

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5 August 2017

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11

Timothy Vartanian

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5 August 2017

Jacob A Sloane

3

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Lena Alexopoulou

object named as

Lena Alexopoulou

2

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Stephen M. Strittmatter

object named as

Stephen M Strittmatter

8

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Richard Flavell

7

object named as

Richard Flavell

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5 August 2017

9

Joseph Volpe

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5 August 2017

Jill S Cameron

1

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5 August 2017

Allitia B DiBernardo

4

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5 August 2017

Yinghua Ma

5

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5 August 2017

Bela Kosaras

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5 August 2017

Richard Sidman

10

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5 August 2017

language of work or name

English

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publication date

1 November 2007

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5 August 2017

published in

Journal of Neuroscience

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5 August 2017

volume

27

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5 August 2017

issue

47

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5 August 2017

page(s)

13033-13041

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Pivotal role for neuronal Toll-like receptors in ischemic brain injury and functional deficits

5 August 2017

cites work

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Central role for MyD88 in the responses of microglia to pathogen-associated molecular patterns

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TLR and NOD2 ligands induce cell proliferation in the rat intact spinal cord

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Virus infection switches TLR-3-positive human neurons to become strong producers of beta interferon

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TLR4, but not TLR2, signals autoregulatory apoptosis of cultured microglia: a critical role of IFN-beta as a decision maker

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PIASy represses TRIF-induced ISRE and NF-kappaB activation but not apoptosis.

8 July 2018

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8 July 2018

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TLR signaling pathways

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mRNA is an endogenous ligand for Toll-like receptor 3.

8 July 2018

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Interferon regulatory factor-3-mediated activation of the interferon-sensitive response element by Toll-like receptor (TLR) 4 but not TLR3 requires the p65 subunit of NF-kappa.

8 July 2018

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LPS-TLR4 signaling to IRF-3/7 and NF-kappaB involves the toll adapters TRAM and TRIF

8 July 2018

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Myelin-associated inhibitors of axonal regeneration in the adult mammalian CNS.

8 July 2018

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Role of adaptor TRIF in the MyD88-independent toll-like receptor signaling pathway

8 July 2018

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Activation of innate immunity in the CNS triggers neurodegeneration through a Toll-like receptor 4-dependent pathway

8 July 2018

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IKKepsilon and TBK1 are essential components of the IRF3 signaling pathway

8 July 2018

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Toll-like receptor 3 mediates a more potent antiviral response than Toll-like receptor 4

8 July 2018

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Poly(I-C)-induced Toll-like receptor 3 (TLR3)-mediated activation of NFkappa B and MAP kinase is through an interleukin-1 receptor-associated kinase (IRAK)-independent pathway employing the signaling components TLR3-TRAF6-TAK1-TAB2-PKR

8 July 2018

1 reference

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IRF3 mediates a TLR3/TLR4-specific antiviral gene program

8 July 2018

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Dangerous liaisons: the role of "danger" signals in the immune response to gene therapy

8 July 2018

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Immunostimulatory CpG-DNA activates murine microglia

8 July 2018

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Innate immune recognition

8 July 2018

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HSP70 as endogenous stimulus of the Toll/interleukin-1 receptor signal pathway

8 July 2018

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Induction of proinflammatory molecules in mice with amyotrophic lateral sclerosis: no requirement for proapoptotic interleukin-1beta in neurodegeneration.

8 July 2018

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Recognition of double-stranded RNA and activation of NF-kappaB by Toll-like receptor 3

8 July 2018

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A fresh look at tumor immunosurveillance and immunotherapy.

8 July 2018

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The Toll receptor family and microbial recognition

8 July 2018

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Dendritic cells: immunological sentinels with a central role in health and disease.

8 July 2018

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Identification of the Nogo inhibitor of axon regeneration as a Reticulon protein

8 July 2018

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Nogo-A is a myelin-associated neurite outgrowth inhibitor and an antigen for monoclonal antibody IN-1

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4313565

A single growth cone is capable of integrating simultaneously presented and functionally distinct molecular cues during target recognition.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4313565

Endotoxin-tolerant mice have mutations in Toll-like receptor 4 (Tlr4)

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4313565

Defective LPS Signaling in C3H/HeJ and C57BL/10ScCr Mice: Mutations in Tlr4 Gene

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4313565

CpG DNA induces sustained IL-12 expression in vivo and resistance to Listeria monocytogenes challenge

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4313565

Molecules inhibiting neurite growth: a minireview

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4313565

The dorsoventral regulatory gene cassette spätzle/Toll/cactus controls the potent antifungal response in Drosophila adults

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4313565

Myelin-associated glycoprotein: a role in myelination and in the inhibition of axonal regeneration?

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4313565

Axonal Elongation into Peripheral Nervous System "Bridges" After Central Nervous System Injury in Adult Rats

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4313565

Axonal regeneration after crush injury of rat central nervous system fibres innervating peripheral nerve grafts

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4313565

Establishment of dorsal-ventral polarity in the Drosophila embryo: the induction of polarity by the Toll gene product

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4313565

Establishment of dorsal-ventral polarity in the Drosophila embryo: genetic studies on the role of the Toll gene product.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4313565

Two membrane protein fractions from rat central myelin with inhibitory properties for neurite growth and fibroblast spreading

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4313565

Oligodendrocytes and CNS myelin are nonpermissive substrates for neurite growth and fibroblast spreading in vitro.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4313565

Axonal guidance in the chick visual system: posterior tectal membranes induce collapse of growth cones from the temporal retina

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4313565

Expression of Toll-like receptor 3 in the human cerebellar cortex in rabies, herpes simplex encephalitis, and other neurological diseases

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4313565

Microglia recognize double-stranded RNA via TLR3.

25 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4313565

Innate immunity triggers oligodendrocyte progenitor reactivity and confines damages to brain injuries.

25 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4313565

TLR signaling tailors innate immune responses in human microglia and astrocytes

25 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4313565

Amyloid beta peptide 1-40 enhances the action of Toll-like receptor-2 and -4 agonists but antagonizes Toll-like receptor-9-induced inflammation in primary mouse microglial cell cultures

25 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4313565

Microglia activation in rat spinal cord by systemic injection of TLR3 and TLR7/8 agonists

25 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4313565

Dose-dependent activation of microglial cells by Toll-like receptor agonists alone and in combination

25 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4313565

Injury primes the innate immune system for enhanced Toll-like receptor reactivity

25 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4313565

BetaAPP and furin mRNA concentrates in immature senile plaques in the brain of Alzheimer patients

25 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4313565

Circulating cell wall components derived from gram-negative, not gram-positive, bacteria cause a profound induction of the gene-encoding Toll-like receptor 2 in the CNS.

25 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4313565

Predominance of neuronal mRNAs in individual Alzheimer's disease senile plaques

25 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4313565

Towards a unified theory of immunity: dendritic cells, stress proteins and antigen capture.

25 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4313565

Toll, a muscle cell surface molecule, locally inhibits synaptic initiation of the RP3 motoneuron growth cone in Drosophila.

25 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4313565

The Drosophila toll gene functions zygotically and is necessary for proper motoneuron and muscle development.

25 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4313565

An innate sense of danger

25 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4313565

APC-independent activation of NK cells by the Toll-like receptor 3 agonist double-stranded RNA

25 October 2018

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12 December 2020

Axons from CNS neurones regenerate into PNS grafts

1 reference

12 December 2020

A novel role for myelin-associated glycoprotein as an inhibitor of axonal regeneration

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12 December 2020

The toll-like receptor TLR4 is necessary for lipopolysaccharide-induced oligodendrocyte injury in the CNS

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12 December 2020

A mechanism for neurodegeneration induced by group B streptococci through activation of the TLR2/MyD88 pathway in microglia

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12 December 2020

Bacterial DNA as an evolutionary conserved ligand signalling danger of infection to immune cells

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12 December 2020

Soluble myelin-associated glycoprotein (MAG) found in vivo inhibits axonal regeneration

1 reference

12 December 2020

Heat-shock proteins as activators of the innate immune system

1 reference

12 December 2020

10.1523/JNEUROSCI.4290-06.2007

Identifiers

DOI

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5 August 2017

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5 August 2017

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