Pharmacogenetics in drug regulation: promise, potential and pitfalls (Q35038052)

5 August 2017

1 reference

title

Pharmacogenetics in drug regulation: promise, potential and pitfalls (English)

1 reference

5 August 2017

Rashmi R Shah

1

1 reference

5 August 2017

language of work or name

English

0 references

publication date

1 August 2005

1 reference

5 August 2017

number of pages

22

1 reference

Philosophical Transactions of the Royal Society B

inferred from page(s)

published in

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5 August 2017

volume

360

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5 August 2017

issue

1460

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5 August 2017

page(s)

1617-1638

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Clinical consequences of cytochrome P450 2C9 polymorphisms

5 August 2017

cites work

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8 July 2018

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8 July 2018

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8 July 2018

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Pharmacogenetics of antihypertensive drug responses

8 July 2018

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3-Hydroxy-3-methylglutaryl-coenzyme A reductase inhibitors (statins) and genetic variability (single nucleotide polymorphisms) in a hepatic drug uptake transporter: what's it all about?

8 July 2018

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8 July 2018

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Pharmacogenetics of antidepressants and antipsychotics: the contribution of allelic variations to the phenotype of drug response

8 July 2018

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Different inhibitory effect of fluvoxamine on omeprazole metabolism between CYP2C19 genotypes

8 July 2018

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Identification of the gene for vitamin K epoxide reductase

8 July 2018

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Mutations in VKORC1 cause warfarin resistance and multiple coagulation factor deficiency type 2

8 July 2018

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Pharmacogenetic aspects of drug-induced torsade de pointes: potential tool for improving clinical drug development and prescribing

8 July 2018

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Polymorphisms in human MDR1 (P-glycoprotein): recent advances and clinical relevance

8 July 2018

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Transporters and renal drug elimination

8 July 2018

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Individualized medicine - implementation of pharmacogenetic diagnostics in antidepressant drug treatment of major depressive disorders

8 July 2018

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Pharmacogenomics and "individualized drug therapy": high expectations and disappointing achievements

8 July 2018

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Pharmacogenetics of antidepressant medication intolerance

8 July 2018

1 reference

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PM frequencies of major CYPs in Asians and Caucasians

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1569525

The serotonin transporter polymorphism, 5HTTLPR, is associated with a faster response time to sertraline in an elderly population with major depressive disorder

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1569525

Pharmacogenomics of human UDP-glucuronosyltransferase enzymes

8 July 2018

1 reference

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Prospects and limits of pharmacogenetics: the thiopurine methyl transferase (TPMT) experience

8 July 2018

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Pharmacogenetics of the major polymorphic metabolizing enzymes.

8 July 2018

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Genetic variation of human UDP-glucuronosyltransferase: implications in disease and drug glucuronidation

8 July 2018

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Pharmacokinetics of diclofenac and inhibition of cyclooxygenases 1 and 2: no relationship to the CYP2C9 genetic polymorphism in humans

8 July 2018

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Gemfibrozil greatly increases plasma concentrations of cerivastatin

8 July 2018

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Gemfibrozil inhibits CYP2C8-mediated cerivastatin metabolism in human liver microsomes

8 July 2018

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Postmarketing drug dosage changes of 499 FDA-approved new molecular entities, 1980-1999.

8 July 2018

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Pharmacogenomics of organic anion-transporting polypeptides (OATP).

8 July 2018

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CYP2C9 allelic variants: ethnic distribution and functional significance

8 July 2018

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The significance of QT interval in drug development

8 July 2018

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The effect of dihydropyrimidine dehydrogenase deficiency on outcomes with fluorouracil

8 July 2018

1 reference

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Cytochrome p450 phenotyping/genotyping in patients receiving antipsychotics: useful aid to prescribing?

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1569525

CYP2D6 allele frequency in European Caucasians, Asians, Africans and their descendants

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1569525

Omeprazole hydroxylation is inhibited by a single dose of moclobemide in homozygotic EM genotype for CYP2C19

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1569525

Cytochrome P450 2C9 polymorphisms: a comprehensive review of the in-vitro and human data.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1569525

Genetic polymorphism of cytochrome P450 2C9 in a Caucasian and a black African population.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1569525

CYP2D6 and CYP2C19 genotype-based dose recommendations for antidepressants: a first step towards subpopulation-specific dosages

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1569525

Polymorphisms in OATP-C: identification of multiple allelic variants associated with altered transport activity among European- and African-Americans

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1569525

Haplotype variation and linkage disequilibrium in 313 human genes

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1569525

Is cytochrome P450 2C9 genotype associated with NSAID gastric ulceration?

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1569525

Dose discrepancies between the Physicians' Desk Reference and the medical literature, and their possible role in the high incidence of dose-related adverse drug events

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1569525

Molecular basis of ethnic differences in drug disposition and response

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1569525

Current pharmacogenomic approaches to clinical drug development

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1569525

Serotonin transporter polymorphism and response to SSRIs in major depression and relevance to anxiety disorders and substance abuse

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1569525

Sulfation pharmacogenetics: SULT1A1 and SULT1A2 allele frequencies in Caucasian, Chinese and African-American subjects

8 July 2018

1 reference

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Polymorphisms of UDP-glucuronosyltransferase gene and irinotecan toxicity: a pharmacogenetic analysis.

8 July 2018

1 reference

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Pharmacogenetics of cardiac K(+) channels

8 July 2018

1 reference

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Pharmacogenetics and adverse drug reactions

8 July 2018

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Complex promoter and coding region beta 2-adrenergic receptor haplotypes alter receptor expression and predict in vivo responsiveness

8 July 2018

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The effect of polymorphisms of the beta(2)-adrenergic receptor on the response to regular use of albuterol in asthma

8 July 2018

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Suggestions for the nomenclature of human alleles: relevance to ecogenetics, pharmacogenetics and molecular epidemiology

8 July 2018

1 reference

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Genotypic analysis of thiopurine S-methyltransferase in patients with Crohn's disease and severe myelosuppression during azathioprine therapy

8 July 2018

1 reference

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Significant interaction between the nonprescription antihistamine diphenhydramine and the CYP2D6 substrate metoprolol in healthy men with high or low CYP2D6 activity

8 July 2018

1 reference

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Functional polymorphisms of the human multidrug-resistance gene: multiple sequence variations and correlation of one allele with P-glycoprotein expression and activity in vivo

8 July 2018

1 reference

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Drug-induced hepatotoxicity: pharmacokinetic perspectives and strategies for risk reduction

8 July 2018

1 reference

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Inhibition of debrisoquine hydroxylation with quinidine in subjects with three or more functional CYP2D6 genes

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1569525

Linkage disequilibrium and allele-frequency distributions for 114 single-nucleotide polymorphisms in five populations

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1569525

High and variable frequencies of CYP2C19 mutations: medical consequences of poor drug metabolism in Vanuatu and other Pacific islands.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1569525

High frequency of CYP2D6 poor and "intermediate" metabolizers in black populations: a review and preliminary data.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1569525

Proguanil disposition and toxicity in malaria patients from Vanuatu with high frequencies of CYP2C19 mutations

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1569525

Characterization of single-nucleotide polymorphisms in coding regions of human genes

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1569525

Effect of CYP2C19 polymorphism on serum levels of vitamin B12 in patients on long-term omeprazole treatment

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1569525

Intrinsic efficacy of proguanil against falciparum and vivax malaria independent of the metabolite cycloguanil

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1569525

The Ile164 beta2-adrenergic receptor polymorphism adversely affects the outcome of congestive heart failure

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1569525

Cloning and functional expression of a human liver organic cation transporter

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1569525

Female gender as a risk factor for torsades de pointes associated with cardiovascular drugs

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1569525

Interethnic difference in omeprazole's inhibition of diazepam metabolism*

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1569525

A family and population study of the genetic polymorphism of debrisoquine oxidation in a white British population.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1569525

Impaired oxidation of debrisoquine in patients with perhexiline liver injury

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1569525

Impaired oxidation of debrisoquine in patients with perhexiline neuropathy

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1569525

The influence of enzyme induction on polymorphic sparteine oxidation

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1569525

Genetically determined steady-state interaction between encainide and quinidine in patients with arrhythmias

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1569525

Influence of debrisoquine phenotype and of quinidine on mexiletine disposition in man.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1569525

The spectrum of symptoms and QT intervals in carriers of the gene for the long-QT syndrome

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1569525

Defective N-oxidation of sparteine in man: A new pharmacogenetic defect

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1569525

Polymorphic hydroxylation of Debrisoquine in man.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1569525

Relationship of polymorphism in CYP2C9 to genetic susceptibility to diclofenac-induced hepatitis

8 July 2018

1 reference

https://api.crossref.org/works/10.1098%2FRSTB.2005.1693

5-HTTLPR polymorphism of the serotonin transporter gene predicts non-remission in major depression patients treated with citalopram in a 12-weeks follow up study

21 January 2018

1 reference

https://api.crossref.org/works/10.1098%2FRSTB.2005.1693

Pharmacogenetic study of statin therapy and cholesterol reduction

21 January 2018

1 reference

https://api.crossref.org/works/10.1098%2FRSTB.2005.1693

Genetic polymorphisms in MDR1 and CYP3A4 genes in Asians and the influence of MDR1 haplotypes on cyclosporin disposition in heart transplant recipients

21 January 2018

1 reference

https://api.crossref.org/works/10.1098%2FRSTB.2005.1693

Linking pharmacovigilance with pharmacogenetics

21 January 2018

1 reference

https://api.crossref.org/works/10.1098%2FRSTB.2005.1693

Prescription of QT-prolonging drugs in a cohort of about 5 million outpatients

21 January 2018

1 reference

https://api.crossref.org/works/10.1098%2FRSTB.2005.1693

A Gilbert's syndrome UGT1A1 variant confers susceptibility to tranilast-induced hyperbilirubinemia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1098%2FRSTB.2005.1693

Contribution of mrp2 in alterations of canalicular bile formation by the endothelin antagonist bosentan

21 January 2018

1 reference

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Thiopurine S-methyltransferase (TPMT) genotype does not predict adverse drug reactions to thiopurine drugs in patients with inflammatory bowel disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1098%2FRSTB.2005.1693

Pharmacogenetics in the laboratory and the clinic.

21 January 2018

1 reference

https://api.crossref.org/works/10.1098%2FRSTB.2005.1693

Association between CYP2C9 genetic variants and anticoagulation-related outcomes during warfarin therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1098%2FRSTB.2005.1693

Effect of lansoprazole and rabeprazole on tacrolimus pharmacokinetics in healthy volunteers with CYP2C19 mutations

21 January 2018

1 reference

https://api.crossref.org/works/10.1098%2FRSTB.2005.1693

UGT1A1*28 polymorphism as a determinant of irinotecan disposition and toxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1098%2FRSTB.2005.1693

Patient-tailored antiemetic treatment with 5-hydroxytryptamine type 3 receptor antagonists according to cytochrome P-450 2D6 genotypes

21 January 2018

1 reference

https://api.crossref.org/works/10.1098%2FRSTB.2005.1693

Contribution of age, body size, and CYP2C9 genotype to anticoagulant response to warfarin

21 January 2018

1 reference

https://api.crossref.org/works/10.1098%2FRSTB.2005.1693

Beta-adrenoceptor genotype influences the response to carvedilol in patients with congestive heart failure

21 January 2018

1 reference

https://api.crossref.org/works/10.1098%2FRSTB.2005.1693

Identification of a null allele of CYP2C9 in an African-American exhibiting toxicity to phenytoin

21 January 2018

1 reference

https://api.crossref.org/works/10.1098%2FRSTB.2005.1693

Identification of functionally variant MDR1 alleles among European Americans and African Americans

21 January 2018

1 reference

https://api.crossref.org/works/10.1098%2FRSTB.2005.1693

Influence of CYP2C9 polymorphisms on the pharmacokinetics and cholesterol-lowering activity of (-)-3S,5R-fluvastatin and (+)-3R,5S-fluvastatin in healthy volunteers

21 January 2018

1 reference

https://api.crossref.org/works/10.1098%2FRSTB.2005.1693

Impact of the ultrarapid metabolizer genotype of cytochrome P450 2D6 on metoprolol pharmacokinetics and pharmacodynamics

21 January 2018

1 reference

https://api.crossref.org/works/10.1098%2FRSTB.2005.1693

Impact of the CYP2D6 ultrarapid metabolizer genotype on mirtazapine pharmacokinetics and adverse events in healthy volunteers

21 January 2018

1 reference

https://api.crossref.org/works/10.1098%2FRSTB.2005.1693

QTc interval lengthening is related to CYP2D6 hydroxylation capacity and plasma concentration of thioridazine in patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1098%2FRSTB.2005.1693

Interindividual variability in sensitivity to warfarin--Nature or nurture?

21 January 2018

1 reference

https://api.crossref.org/works/10.1098%2FRSTB.2005.1693

Serotonin transporter promoter polymorphism in African Americans : allele frequencies and implications for treatment

21 January 2018

1 reference

https://api.crossref.org/works/10.1098%2FRSTB.2005.1693

TP53 mutations in early-stage ovarian carcinoma, relation to long-term survival

21 January 2018

1 reference

https://api.crossref.org/works/10.1098%2FRSTB.2005.1693

Effects of grapefruit juice on intestinal P-glycoprotein: evaluation using digoxin in humans.

21 January 2018

1 reference

https://api.crossref.org/works/10.1098%2FRSTB.2005.1693

Serotonin transporter polymorphisms and adverse effects with fluoxetine treatment

21 January 2018

1 reference

https://api.crossref.org/works/10.1098%2FRSTB.2005.1693

CYP2C9 genotypes and dose requirements during the induction phase of oral anticoagulant therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1098%2FRSTB.2005.1693

In vitro characterization of hepatic flavopiridol metabolism using human liver microsomes and recombinant UGT enzymes

21 January 2018

1 reference

https://api.crossref.org/works/10.1098%2FRSTB.2005.1693

Time trends in the coprescribing of cisapride and contraindicated drugs in Umbria, Italy

21 January 2018

1 reference

https://api.crossref.org/works/10.1098%2FRSTB.2005.1693

CYP2D6 genotype: impact on adverse effects and nonresponse during treatment with antidepressants-a pilot study

21 January 2018

1 reference

https://api.crossref.org/works/10.1098%2FRSTB.2005.1693

Concomitant use of antipsychotics and drugs that may prolong the QT interval

21 January 2018

1 reference

https://api.crossref.org/works/10.1098%2FRSTB.2005.1693

Relevance of different UGT1A1 polymorphisms in irinotecan-induced toxicity: a molecular and clinical study of 75 patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1098%2FRSTB.2005.1693

Pharmacokinetics of the antianginal agent perhexiline: relationship between metabolic ratio and steady-state dose

21 January 2018

1 reference

https://api.crossref.org/works/10.1098%2FRSTB.2005.1693

Comprehensive analysis of thiopurine S-methyltransferase phenotype-genotype correlation in a large population of German-Caucasians and identification of novel TPMT variants

21 January 2018

1 reference

https://api.crossref.org/works/10.1098%2FRSTB.2005.1693

Azathioprine therapy and adverse drug reactions in patients with inflammatory bowel disease: impact of thiopurine S-methyltransferase polymorphism

21 January 2018

1 reference

https://api.crossref.org/works/10.1098%2FRSTB.2005.1693

Genetical and geographic studies on isoniazid inactivation

21 January 2018

1 reference

https://api.crossref.org/works/10.1098%2FRSTB.2005.1693

Effects of concomitant fluvoxamine on the metabolism of alprazolam in Japanese psychiatric patients: interaction with CYP2C19 mutated alleles

21 January 2018

1 reference

https://api.crossref.org/works/10.1098%2FRSTB.2005.1693

Population differences in S-warfarin metabolism between CYP2C9 genotype-matched Caucasian and Japanese patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1098%2FRSTB.2005.1693

5'-Flanking region polymorphisms of CYP2C9 and their relationship to S-warfarin metabolism in white and Japanese patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1098%2FRSTB.2005.1693

Variations in the 5-hydroxytryptamine type 3B receptor gene as predictors of the efficacy of antiemetic treatment in cancer patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1098%2FRSTB.2005.1693

Pharmacogenetics--expectations and reality

21 January 2018

1 reference

https://api.crossref.org/works/10.1098%2FRSTB.2005.1693

The effect of genetic polymorphism of cytochrome P450 CYP2C9 on phenytoin dose requirement

21 January 2018

1 reference

https://api.crossref.org/works/10.1098%2FRSTB.2005.1693

Genetic and environmental risk factors for oral anticoagulant overdose

21 January 2018

1 reference

https://api.crossref.org/works/10.1098%2FRSTB.2005.1693

St John's wort induces both cytochrome P450 3A4-catalyzed sulfoxidation and 2C19-dependent hydroxylation of omeprazole

21 January 2018

1 reference

https://api.crossref.org/works/10.1098%2FRSTB.2005.1693

A study to survey susceptible genetic factors responsible for troglitazone‐associated hepatotoxicity in Japanese patients with type 2 diabetes mellitus

21 January 2018

1 reference

https://api.crossref.org/works/10.1098%2FRSTB.2005.1693

Cytochrome P450 2D6 and antidepressant toxicity and response: what is the evidence?

21 January 2018

1 reference

https://api.crossref.org/works/10.1098%2FRSTB.2005.1693

Postmarketing reports of QT prolongation and ventricular arrhythmia in association with cisapride and Food and Drug Administration regulatory actions

21 January 2018

1 reference

https://api.crossref.org/works/10.1098%2FRSTB.2005.1693

Effects of fluvoxamine on lansoprazole pharmacokinetics in relation to CYP2C19 genotypes

21 January 2018

1 reference

https://api.crossref.org/works/10.1098%2FRSTB.2005.1693

Clinical relevance of N-acetyltransferase type 2 (NAT2) genetic polymorphism

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1569525

Phenol sulphotransferase SULT1A1 polymorphism: molecular diagnosis and allele frequencies in Caucasian and African populations

25 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1569525

Ethnic distribution of slow acetylator mutations in the polymorphic N-acetyltransferase (NAT2) gene

25 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1569525

Ethnic differences in the linkage disequilibrium and distribution of single-nucleotide polymorphisms in 35 candidate genes for cardiovascular diseases

25 October 2018

1 reference

https://api.crossref.org/works/10.1098%2FRSTB.2005.1693

Congenital deficiency of vitamin K dependent coagulation factors in two families presents as a genetic defect of the vitamin K-epoxide-reductase-complex

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1569525

Medical implications of HGP's sequence of chromosome 22

9 December 2018

1 reference

12 December 2020

Bioinformatics research on inter-racial difference in drug metabolism I. Analysis on frequencies of mutant alleles and poor metabolizers on CYP2D6 and CYP2C19

1 reference

12 December 2020

Quinidine-enhanced beta-blockade during treatment with propafenone in extensive metabolizer human subjects

1 reference

12 December 2020

beta2-Adrenergic receptor haplotypes in mild, moderate and fatal/near fatal asthma

1 reference

12 December 2020

International Conference on Harmonisation; guidance on ethnic factors in the acceptability of foreign clinical data; availability--FDA. Notice

1 reference

12 December 2020

Pharmacogenetic association between ALOX5 promoter genotype and the response to anti-asthma treatment

1 reference

12 December 2020

Serotonin transporter gene polymorphism and antidepressant response

1 reference

12 December 2020

Allelic variation in the serotonin transporter promoter affects onset of paroxetine treatment response in late-life depression

1 reference

12 December 2020

Low penetrance in the long-QT syndrome: clinical impact

1 reference

12 December 2020

10-Hydroxylation of nortriptyline in white persons with 0, 1, 2, 3, and 13 functional CYP2D6 genes

1 reference

12 December 2020

Hepatobiliary transport kinetics of HSR-903, a new quinolone antibacterial agent

1 reference

12 December 2020

Determination of thiopurine methyltransferase genotype or phenotype optimizes initial dosing of azathioprine for the treatment of Crohn's disease

1 reference

12 December 2020

Induction of CYP2D6 in pregnancy

1 reference

12 December 2020

Prospective CYP2D6 genotyping as an exclusion criterion for enrollment of a phase III clinical trial

1 reference

12 December 2020

The frequency and distribution of thiopurine methyltransferase alleles in Caucasian and Asian populations

1 reference

12 December 2020

Contraindicated use of cisapride: impact of food and drug administration regulatory action

1 reference

12 December 2020

Consequences of rifampicin treatment on propafenone disposition in extensive and poor metabolizers of CYP2D6

1 reference

12 December 2020

Genetic control of isoniazid metabolism in man

1 reference

12 December 2020

Human pharmacogenetics of methyl conjugation

1 reference

12 December 2020

Molecular genetics of the long QT syndrome: two novel mutations of the KVLQT1 gene and phenotypic expression of the mutant gene in a large kindred

1 reference

12 December 2020

Concentration-related pharmacodynamic effects of thioridazine and its metabolites in humans

1 reference

12 December 2020

Flavopiridol metabolism in cancer patients is associated with the occurrence of diarrhea

1 reference

12 December 2020

In vivo modulation of CYP enzymes by quinidine and rifampin

1 reference

12 December 2020

Polymorphism of the thiopurine S-methyltransferase gene in African-Americans

1 reference

12 December 2020

Inhibition by paroxetine of desipramine metabolism in extensive but not in poor metabolizers of sparteine

1 reference

12 December 2020

Impact of ethnic origin and quinidine coadministration on codeine's disposition and pharmacodynamic effects

1 reference

12 December 2020

Identifiers

DOI

10.1098/RSTB.2005.1693

1 reference

5 August 2017

1 reference

5 August 2017

1 reference