Role of oxidants in male infertility: rationale, significance, and treatment (Q35040336)

6 August 2017

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title

Role of oxidants in male infertility: rationale, significance, and treatment (English)

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6 August 2017

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Ashok Agarwal

1

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PubMed ID

12516754

6 August 2017

Ramadan A Saleh

series ordinal

2

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6 August 2017

1 November 2002

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Urologic Clinics of North America

6 August 2017

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6 August 2017

29

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6 August 2017

4

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6 August 2017

817-827

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Role of reactive oxygen species in male infertility

6 August 2017

1 reference

https://api.crossref.org/works/10.1016%2FS0094-0143%2802%2900081-2

7 January 2021

Impact of reactive oxygen species on spermatozoa: a balancing act between beneficial and detrimental effects.

1 reference

https://api.crossref.org/works/10.1016%2FS0094-0143%2802%2900081-2

7 January 2021

Strategies of antioxidant defense

1 reference

https://api.crossref.org/works/10.1016%2FS0094-0143%2802%2900081-2

7 January 2021

Relative impact of oxidative stress on male reproductive function

1 reference

https://api.crossref.org/works/10.1016%2FS0094-0143%2802%2900081-2

7 January 2021

The Amoroso Lecture. The human spermatozoon--a cell in crisis?

1 reference

https://api.crossref.org/works/10.1016%2FS0094-0143%2802%2900081-2

7 January 2021

Reactive oxygen species and human spermatozoa: physiology and pathology

1 reference

https://api.crossref.org/works/10.1016%2FS0094-0143%2802%2900081-2

7 January 2021

Seminal reactive oxygen species and sperm motility and morphology in men with spinal cord injury

1 reference

https://api.crossref.org/works/10.1016%2FS0094-0143%2802%2900081-2

7 January 2021

Differential incorporation of fatty acids into and peroxidative loss of fatty acids from phospholipids of human spermatozoa

1 reference

https://api.crossref.org/works/10.1016%2FS0094-0143%2802%2900081-2

7 January 2021

Formation of reactive oxygen species in spermatozoa of infertile patients

1 reference

https://api.crossref.org/works/10.1016%2FS0094-0143%2802%2900081-2

7 January 2021

Reactive oxygen species in semen of infertile patients: levels of superoxide dismutase- and catalase-like activities in seminal plasma and spermatozoa

1 reference

https://api.crossref.org/works/10.1016%2FS0094-0143%2802%2900081-2

7 January 2021

Increased oxidative deoxyribonucleic acid damage in the spermatozoa of infertile male patients

1 reference

https://api.crossref.org/works/10.1016%2FS0094-0143%2802%2900081-2

7 January 2021

Detection of deoxyribonucleic acid fragmentation in human sperm: correlation with fertilization in vitro.

1 reference

https://api.crossref.org/works/10.1016%2FS0094-0143%2802%2900081-2

7 January 2021

Origin of reactive oxygen species in human semen: spermatozoa or leucocytes?

1 reference

https://api.crossref.org/works/10.1016%2FS0094-0143%2802%2900081-2

7 January 2021

Reactive oxygen species and human spermatozoa: analysis of the cellular mechanisms involved in luminol- and lucigenin-dependent chemiluminescence

1 reference

https://api.crossref.org/works/10.1016%2FS0094-0143%2802%2900081-2

7 January 2021

Differential production of reactive oxygen species by subsets of human spermatozoa at different stages of maturation

1 reference

https://api.crossref.org/works/10.1016%2FS0094-0143%2802%2900081-2

7 January 2021

Varicocele is associated with elevated spermatozoal reactive oxygen species production and diminished seminal plasma antioxidant capacity

1 reference

https://api.crossref.org/works/10.1016%2FS0094-0143%2802%2900081-2

7 January 2021

Evaluation of a spectrophotometric assay for the measurement of malondialdehyde and 4-hydroxyalkenals in human spermatozoa: relationships with semen quality and sperm function.

1 reference

https://api.crossref.org/works/10.1016%2FS0094-0143%2802%2900081-2

7 January 2021

Sperm plasma membrane remodeling during spermiogenetic maturation in men: relationship among plasma membrane beta 1,4-galactosyltransferase, cytoplasmic creatine phosphokinase, and creatine phosphokinase isoform ratios.

1 reference

https://api.crossref.org/works/10.1016%2FS0094-0143%2802%2900081-2

7 January 2021

Reactive oxygen species generation by human spermatozoa is induced by exogenous NADPH and inhibited by the flavoprotein inhibitors diphenylene iodonium and quinacrine

1 reference

https://api.crossref.org/works/10.1016%2FS0094-0143%2802%2900081-2

7 January 2021

Reactive oxygen species released by activated neutrophils, but not by deficient spermatozoa, are sufficient to affect normal sperm motility

1 reference

https://api.crossref.org/works/10.1016%2FS0094-0143%2802%2900081-2

7 January 2021

Effect of sperm washing on levels of reactive oxygen species in semen

1 reference

https://api.crossref.org/works/10.1016%2FS0094-0143%2802%2900081-2

7 January 2021

A method of human semen centrifugation to minimize the iatrogenic sperm injuries caused by reactive oxygen species

1 reference

https://api.crossref.org/works/10.1016%2FS0094-0143%2802%2900081-2

7 January 2021

Incidence and level of seminal reactive oxygen species in normal men

1 reference

https://api.crossref.org/works/10.1016%2FS0094-0143%2802%2900081-2

7 January 2021

Characterization of subsets of human spermatozoa at different stages of maturation: implications in the diagnosis and treatment of male infertility.

1 reference

https://api.crossref.org/works/10.1016%2FS0094-0143%2802%2900081-2

7 January 2021

Analysis of the relationship between reactive oxygen species production and leucocyte infiltration in fractions of human semen separated on Percoll gradients

1 reference

https://api.crossref.org/works/10.1016%2FS0094-0143%2802%2900081-2

7 January 2021

Infections in the male genital tract and reactive oxygen species

1 reference

https://api.crossref.org/works/10.1016%2FS0094-0143%2802%2900081-2

7 January 2021

Positive myeloperoxidase staining (Endtz test) as an indicator of excessive reactive oxygen species formation in semen

1 reference

https://api.crossref.org/works/10.1016%2FS0094-0143%2802%2900081-2

7 January 2021

Nonspermatozoal cells in semen: relationship to other semen parameters and fertility status of the couple

1 reference

https://api.crossref.org/works/10.1016%2FS0094-0143%2802%2900081-2

7 January 2021

Immunohistologic characterization and quantitation of leukocyte subpopulations in human semen

1 reference

https://api.crossref.org/works/10.1016%2FS0094-0143%2802%2900081-2

7 January 2021

Relationship between oxidative stress, semen characteristics, and clinical diagnosis in men undergoing infertility investigation

1 reference

https://api.crossref.org/works/10.1016%2FS0094-0143%2802%2900081-2

7 January 2021

Free radicals in biological systems--a review orientated to inflammatory processes

1 reference

https://api.crossref.org/works/10.1016%2FS0094-0143%2802%2900081-2

7 January 2021

Phagocytic killing of microorganisms by radical processes: consequences of the reaction of hydroxyl radicals with chloride yielding chlorine atoms

1 reference

https://api.crossref.org/works/10.1016%2FS0094-0143%2802%2900081-2

7 January 2021

Leukocytospermia is associated with increased reactive oxygen species production by human spermatozoa

1 reference

https://api.crossref.org/works/10.1016%2FS0094-0143%2802%2900081-2

7 January 2021

Generation of reactive oxygen species, lipid peroxidation, and human sperm function

1 reference

https://api.crossref.org/works/10.1016%2FS0094-0143%2802%2900081-2

7 January 2021

Tell me about free radicals, doctor: a review

1 reference

https://api.crossref.org/works/10.1016%2FS0094-0143%2802%2900081-2

7 January 2021

Relationship between iron-catalysed lipid peroxidation potential and human sperm function.

1 reference

https://api.crossref.org/works/10.1016%2FS0094-0143%2802%2900081-2

7 January 2021

Relationship of sperm parameters with levels of reactive oxygen species in semen specimens

1 reference

https://api.crossref.org/works/10.1016%2FS0094-0143%2802%2900081-2

7 January 2021

Reactive oxygen species, lipid peroxidation and enzymatic defence systems in human spermatozoa

1 reference

https://api.crossref.org/works/10.1016%2FS0094-0143%2802%2900081-2

7 January 2021

Iatrogenic DNA damage induced in human spermatozoa during sperm preparation: protective significance of seminal plasma

1 reference

https://api.crossref.org/works/10.1016%2FS0094-0143%2802%2900081-2

7 January 2021

Effects of hydrogen peroxide on DNA and plasma membrane integrity of human spermatozoa

1 reference

https://api.crossref.org/works/10.1016%2FS0094-0143%2802%2900081-2

7 January 2021

Reactive oxygen species: potential cause for DNA fragmentation in human spermatozoa.

1 reference

https://api.crossref.org/works/10.1016%2FS0094-0143%2802%2900081-2

7 January 2021

Oxidative damage to DNA in human spermatozoa does not preclude pronucleus formation at intracytoplasmic sperm injection.

1 reference

https://api.crossref.org/works/10.1016%2FS0094-0143%2802%2900081-2

7 January 2021

Origin of DNA damage in ejaculated human spermatozoa.

1 reference

https://api.crossref.org/works/10.1016%2FS0094-0143%2802%2900081-2

7 January 2021

Spontaneous lipid peroxidation and production of hydrogen peroxide and superoxide in human spermatozoa. Superoxide dismutase as major enzyme protectant against oxygen toxicity

1 reference

https://api.crossref.org/works/10.1016%2FS0094-0143%2802%2900081-2

7 January 2021

Ascorbic acid protects against endogenous oxidative DNA damage in human sperm

1 reference

https://api.crossref.org/works/10.1016%2FS0094-0143%2802%2900081-2

7 January 2021

Vitamin E levels in seminal plasma can be elevated by oral administration of vitamin E in infertile men

1 reference

https://api.crossref.org/works/10.1016%2FS0094-0143%2802%2900081-2

7 January 2021

Taurine, hypotaurine, epinephrine and albumin inhibit lipid peroxidation in rabbit spermatozoa and protect against loss of motility

1 reference

https://api.crossref.org/works/10.1016%2FS0094-0143%2802%2900081-2

7 January 2021

Total antioxidant capacity of seminal plasma is different in fertile and infertile men

1 reference

https://api.crossref.org/works/10.1016%2FS0094-0143%2802%2900081-2

7 January 2021

How to characterize a biological antioxidant

1 reference

https://api.crossref.org/works/10.1016%2FS0094-0143%2802%2900081-2

7 January 2021

The pecking order of free radicals and antioxidants: lipid peroxidation, alpha-tocopherol, and ascorbate

1 reference

https://api.crossref.org/works/10.1016%2FS0094-0143%2802%2900081-2

7 January 2021

Effect of seminal oxidative stress on fertility after vasectomy reversal

1 reference

https://api.crossref.org/works/10.1016%2FS0094-0143%2802%2900081-2

7 January 2021

The reactive oxygen species-total antioxidant capacity score is a new measure of oxidative stress to predict male infertility

1 reference

https://api.crossref.org/works/10.1016%2FS0094-0143%2802%2900081-2

7 January 2021

Seminal oxidative stress in patients with chronic prostatitis

1 reference

https://api.crossref.org/works/10.1016%2FS0094-0143%2802%2900081-2

7 January 2021

Antioxidant treatment of patients with asthenozoospermia or moderate oligoasthenozoospermia with high-dose vitamin C and vitamin E: a randomized, placebo-controlled, double-blind study

1 reference

https://api.crossref.org/works/10.1016%2FS0094-0143%2802%2900081-2

7 January 2021

Is antioxidant therapy a promising strategy to improve human reproduction? Are anti-oxidants useful in the treatment of male infertility?

1 reference

https://api.crossref.org/works/10.1016%2FS0094-0143%2802%2900081-2

7 January 2021

Andrology: Glutathione treatment of dyspermia: effect on the lipoperoxidation process

1 reference

https://api.crossref.org/works/10.1016%2FS0094-0143%2802%2900081-2

7 January 2021

Randomised trial of clomiphene citrate treatment and vitamin C for male infertility

1 reference

https://api.crossref.org/works/10.1016%2FS0094-0143%2802%2900081-2

7 January 2021

The effect of antioxidant treatment on human spermatozoa and fertilization rate in an in vitro fertilization program

1 reference

https://api.crossref.org/works/10.1016%2FS0094-0143%2802%2900081-2

7 January 2021

Excretion of alpha-tocopherol into human seminal plasma after oral administration

1 reference

https://api.crossref.org/works/10.1016%2FS0094-0143%2802%2900081-2

7 January 2021

The effects of combined conventional treatment, oral antioxidants and essential fatty acids on sperm biology in subfertile men.

1 reference

https://api.crossref.org/works/10.1016%2FS0094-0143%2802%2900081-2

7 January 2021

Antioxidant treatment for male subfertility: a promise that remains unfulfilled

1 reference

https://api.crossref.org/works/10.1016%2FS0094-0143%2802%2900081-2

7 January 2021

Antioxidants may protect against infertility

1 reference

https://api.crossref.org/works/10.1016%2FS0094-0143%2802%2900081-2

7 January 2021

The effects of antioxidant supplementation during Percoll preparation on human sperm DNA integrity

1 reference

https://api.crossref.org/works/10.1016%2FS0094-0143%2802%2900081-2

7 January 2021

Glutathione as a treatment for male infertility

1 reference

https://api.crossref.org/works/10.1016%2FS0094-0143%2802%2900081-2

7 January 2021

Significance of reactive oxygen species and antioxidants in defining the efficacy of sperm preparation techniques

1 reference

https://api.crossref.org/works/10.1016%2FS0094-0143%2802%2900081-2

7 January 2021

A double-blind randomized placebo cross-over controlled trial using the antioxidant vitamin E to treat reactive oxygen species associated male infertility.

1 reference

https://api.crossref.org/works/10.1016%2FS0094-0143%2802%2900081-2

7 January 2021

Antioxidant supplementation in vitro does not improve human sperm motility

1 reference

https://api.crossref.org/works/10.1016%2FS0094-0143%2802%2900081-2

7 January 2021

Comparison of individual antioxidants of sperm and seminal plasma in fertile and infertile men

1 reference

https://api.crossref.org/works/10.1016%2FS0094-0143%2802%2900081-2

7 January 2021

10.1016/S0094-0143(02)00081-2

Identifiers

DOI

1 reference

6 August 2017

1 reference

PubMed ID

12516754