Characterization of SB-269970-A, a selective 5-HT(7) receptor antagonist (Q35042314)

6 August 2017

title

Characterization of SB-269970-A, a selective 5-HT(7) receptor antagonist (English)

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6 August 2017

J J Hagan

1

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6 August 2017

G W Price

2

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6 August 2017

P Jeffrey

3

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6 August 2017

N J Deeks

4

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6 August 2017

T Stean

5

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6 August 2017

D Piper

6

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6 August 2017

M I Smith

7

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6 August 2017

N Upton

8

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6 August 2017

A D Medhurst

9

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6 August 2017

D N Middlemiss

10

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6 August 2017

G J Riley

11

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6 August 2017

P J Lovell

12

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6 August 2017

S M Bromidge

13

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6 August 2017

D R Thomas

14

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6 August 2017

language of work or name

English

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publication date

1 June 2000

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British Journal of Pharmacology

6 August 2017

published in

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6 August 2017

volume

130

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6 August 2017

issue

3

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6 August 2017

page(s)

539-548

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A novel, potent, and selective 5-HT(7) antagonist: (R)-3-(2-(2-(4-methylpiperidin-1-yl)ethyl)pyrrolidine-1-sulfonyl) phen ol (SB-269970).

6 August 2017

cites work

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5-CT stimulation of adenylyl cyclase activity in guinea-pig hippocampus: evidence for involvement of 5-HT7 and 5-HT1A receptors

8 July 2018

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Orexin A activates locus coeruleus cell firing and increases arousal in the rat.

8 July 2018

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Tetrahydrobenzindoles: selective antagonists of the 5-HT7 receptor

8 July 2018

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Functional characterisation of the human cloned 5-HT7 receptor (long form); antagonist profile of SB-258719

8 July 2018

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(R)-3,N-dimethyl-N-[1-methyl-3-(4-methyl-piperidin-1-yl) propyl]benzenesulfonamide: the first selective 5-HT7 receptor antagonist

8 July 2018

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Critical analysis of the theories advanced to explain short REM sleep latencies and other sleep anomalies in several psychiatric conditions

8 July 2018

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Human serotonin 5-HT7 receptor: cloning and pharmacological characterisation of two receptor variants

8 July 2018

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The 5-HT7 receptor: orphan found

8 July 2018

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Four 5-hydroxytryptamine7 (5-HT7) receptor isoforms in human and rat produced by alternative splicing: species differences due to altered intron-exon organization

8 July 2018

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Functional, endogenously expressed 5-hydroxytryptamine 5-ht7 receptors in human vascular smooth muscle cells

8 July 2018

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A receptor autoradiographic and in situ hybridization analysis of the distribution of the 5-ht7 receptor in rat brain

8 July 2018

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A novel adenylyl cyclase-activating serotonin receptor (5-HT7) implicated in the regulation of mammalian circadian rhythms

8 July 2018

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Molecular cloning, characterization, and localization of a high-affinity serotonin receptor (5-HT7) activating cAMP formation

8 July 2018

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Molecular cloning of a mammalian serotonin receptor that activates adenylate cyclase.

8 July 2018

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Molecular cloning and expression of a 5-hydroxytryptamine7 serotonin receptor subtype

8 July 2018

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Cloning of a novel human serotonin receptor (5-HT7) positively linked to adenylate cyclase

8 July 2018

1 reference

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International Union of Pharmacology classification of receptors for 5-hydroxytryptamine (Serotonin)

8 July 2018

1 reference

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Binding of typical and atypical antipsychotic agents to 5-hydroxytryptamine-6 and 5-hydroxytryptamine-7 receptors

8 July 2018

1 reference

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Characterization and distribution of putative 5-ht7 receptors in guinea-pig brain

8 July 2018

1 reference

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Cloning and expression of a 5-hydroxytryptamine7 receptor positively coupled to adenylyl cyclase

8 July 2018

1 reference

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Relationship between the inhibition constant (K1) and the concentration of inhibitor which causes 50 per cent inhibition (I50) of an enzymatic reaction

8 July 2018

1 reference

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Short-term effects of fluoxetine and trifluoromethylphenylpiperazine on electroencephalographic sleep in the rat.

8 July 2018

1 reference

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Pharmacological studies with SK&F 93944 (temelastine), a novel histamine H1-receptor antagonist with negligible ability to penetrate the central nervous system

8 July 2018

1 reference

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Terminal Autoreceptor Control of 5‐Hydroxytryptamine Release as Measured by In Vivo Microdialysis in the Conscious Guinea‐Pig

8 July 2018

1 reference

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8 July 2018

Adenylate cyclase assay

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1572114

Pindolol-insensitive [3H]-5-hydroxytryptamine binding in the rat hypothalamus; identity with 5-hydroxytryptamine7 receptors

8 July 2018

1 reference

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Involvement of the 5-HT7 receptor in craniovascular vasodilatation: potential impact in migraine.

25 October 2018

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Stimulation of 5-HT1B receptors causes hypothermia in the guinea pig.

25 October 2018

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5-HT7 receptors mediate serotonergic effects on light-sensitive suprachiasmatic nucleus neurons

25 October 2018

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Assignment of the 5HT7 receptor gene (HTR7) to chromosome 10q and exclusion of genetic linkage with tourette syndrome

25 October 2018

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12 December 2020

Allelic discrimination using fluorogenic probes and the 5' nuclease assay

1 reference

12 December 2020

Stimulation of central 5-HT1D receptors causes hypothermia in the guinea-pig.

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12 December 2020

Identification of 5-hydroxytryptamine7 receptor binding sites in rat hypothalamus: sensitivity to chronic antidepressant treatment

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12 December 2020

Four 5-Hydroxytryptamine7 (5-HT7) Receptor Isoforms in Human and Rat Produced by Alternative Splicing: Species Differences Due to Altered Intron-Exon Organization

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FSJ.BJP.0703357

7 January 2021

inferred from DOI database lookup

Identifiers

DOI

10.1038/SJ.BJP.0703357

1 reference

6 August 2017

1 reference

6 August 2017

1 reference