On the regulation of ischaemia-induced glutamate efflux from rat cortex by GABA; in vitro studies with GABA, clomethiazole and pentobarbitone. (Q35042403)

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scientific article published in July 2000

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English	On the regulation of ischaemia-induced glutamate efflux from rat cortex by GABA; in vitro studies with GABA, clomethiazole and pentobarbitone.	scientific article published in July 2000

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scholarly article

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8 November 2019

On the regulation of ischaemia-induced glutamate efflux from rat cortex by GABA; in vitro studies with GABA, clomethiazole and pentobarbitone (English)

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8 November 2019

David G Lambert

3

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8 November 2019

Atticus H Hainsworth

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8 November 2019

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R M Nelson

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8 November 2019

A R Green

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8 November 2019

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1 July 2000

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8 November 2019

British Journal of Pharmacology

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8 November 2019

130

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8 November 2019

5

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8 November 2019

1124-1130

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8 November 2019

GABA potentiation: a logical pharmacological approach for the treatment of acute ischaemic stroke

1 reference

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The metabolism of clomethiazole in gerbils and the neuroprotective and sedative activity of the metabolites

1 reference

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Clinical trials with neuroprotective drugs in acute ischaemic stroke: are we doing the right thing?

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Pathobiology of ischaemic stroke: an integrated view

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The changing landscape of ischaemic brain injury mechanisms.

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Intrinsic optical signaling denoting neuronal damage in response to acute excitotoxic insult by domoic acid in the hippocampal slice

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Release of endogenous glutamate, aspartate, GABA, and taurine from hippocampal slices from adult and developing mice under cell-damaging conditions

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Calcium in ischemic cell death

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Interactions between loreclezole, chlormethiazole and pentobarbitone at GABA(A) receptors: functional and binding studies

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8 July 2018

GABA and neuroprotection

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8 July 2018

NMDA antagonists: their role in neuroprotection

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8 July 2018

Techniques for assessing neuroprotective drugs in vitro

1 reference

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8 July 2018

Techniques for examining neuroprotective drugs in vivo

1 reference

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8 July 2018

Mechanism of glutamate release from rat hippocampal slices during in vitro ischemia.

1 reference

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8 July 2018

mu- and kappa-opioids inhibit K+ evoked glutamate release from rat cerebrocortical slices.

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The human neuroblastoma cell line, IMR-32 possesses a GABAA receptor lacking the benzodiazepine modulatory site

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8 July 2018

Attenuation by chlormethiazole administration of the rise in extracellular amino acids following focal ischaemia in the cerebral cortex of the rat.

1 reference

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8 July 2018

Animal models of acute ischaemic stroke: can they predict clinically successful neuroprotective drugs?

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8 July 2018

The protective action of chlormethiazole against ischaemia‐induced neurodegeneration in gerbils when infused at doses having little sedative or anticonvulsant activity

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8 July 2018

Triggering and execution of neuronal death in brain ischaemia: two phases of glutamate release by different mechanisms

1 reference

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8 July 2018

Two distinct interactions of barbiturates and chlormethiazole with the GABAA receptor complex in rat cuneate nucleus in vitro

1 reference

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8 July 2018

Diazepam and (--)-pentobarbital: fluctuation analysis reveals different mechanisms for potentiation of gamma-aminobutyric acid responses in cultured central neurons

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8 July 2018

Ca2+-dependent and Ca2+-independent glutamate release, energy status and cytosolic free Ca2+ concentration in isolated nerve terminals following metabolic inhibition: possible relevance to hypoglycaemia and anoxia.

1 reference

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8 July 2018

Rodent models of cerebral ischemia

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8 July 2018

The modulation by chlormethiazole of the GABAA-receptor complex in rat brain

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Protection against ischaemic neuronal damage by drugs acting on excitatory neurotransmission

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Neuroprotective activity of chlormethiazole following transient forebrain ischaemia in the gerbil

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Functional benefit from clomethiazole treatment after focal cerebral ischemia in a nonhuman primate species.

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1 reference

https://pubmed.ncbi.nlm.nih.gov/10882398

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inferred from PubMed ID database lookup

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1 reference

https://pubmed.ncbi.nlm.nih.gov/10882398

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The neuroprotective effect of chlormethiazole on ischaemic neuronal damage following permanent middle cerebral artery ischaemia in the rat

1 reference

https://pubmed.ncbi.nlm.nih.gov/10882398

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Amino-acid release from human cerebral cortex during simulated ischaemia in vitro

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A behavioural and neurochemical study in rats of the pharmacology of loreclezole, a novel allosteric modulator of the GABAA receptor

1 reference

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1 reference

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10.1038/SJ.BJP.0703398

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8 November 2019

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8 November 2019

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8 November 2019

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