Involvement of N-6 adenine-specific DNA methyltransferase 1 (N6AMT1) in arsenic biomethylation and its role in arsenic-induced toxicity (Q35044729)

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19 January 2020

title

Involvement of N-6 adenine-specific DNA methyltransferase 1 (N6AMT1) in arsenic biomethylation and its role in arsenic-induced toxicity (English)

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19 January 2020

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ChEBI release 2020-05-28

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6

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19 January 2020

author name string

Xuefeng Ren

1

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19 January 2020

Maria Aleshin

2

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19 January 2020

William J Jo

3

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19 January 2020

Russel Dills

4

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19 January 2020

David A Kalman

5

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19 January 2020

Martyn T Smith

7

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19 January 2020

Luoping Zhang

8

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19 January 2020

publication date

30 December 2010

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19 January 2020

number of pages

7

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Environmental Health Perspectives

inferred from page(s)

published in

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19 January 2020

volume

119

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19 January 2020

issue

6

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19 January 2020

page(s)

771-777

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Disruption of the arsenic (+3 oxidation state) methyltransferase gene in the mouse alters the phenotype for methylation of arsenic and affects distribution and retention of orally administered arsenate.

19 January 2020

cites work

1 reference

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Comparative functional genomic analysis identifies distinct and overlapping sets of genes required for resistance to monomethylarsonous acid (MMAIII) and arsenite (AsIII) in yeast

8 July 2018

1 reference

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Association of AS3MT polymorphisms and the risk of premalignant arsenic skin lesions

8 July 2018

1 reference

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A review of human carcinogens--Part C: metals, arsenic, dusts, and fibres

8 July 2018

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Health effects of arsenic and chromium in drinking water: recent human findings

8 July 2018

1 reference

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PFP: Automated prediction of gene ontology functional annotations with confidence scores using protein sequence data

8 July 2018

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HemK2 protein, encoded on human chromosome 21, methylates translation termination factor eRF1

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3114810

Toxicity of inorganic arsenic and its metabolites on haematopoietic progenitors "in vitro": comparison between species and sexes

8 July 2018

1 reference

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Immortalized human urothelial cells as a model of arsenic-induced bladder cancer

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3114810

Arsenic (+3 oxidation state) methyltransferase and the methylation of arsenicals.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3114810

Human health effects from chronic arsenic poisoning--a review

8 July 2018

1 reference

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Monomethylarsonous acid induces transformation of human bladder cells

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3114810

Arsenic methylation and bladder cancer risk in case-control studies in Argentina and the United States

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3114810

Human arsenic methyltransferase (AS3MT) pharmacogenetics: gene resequencing and functional genomics studies

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3114810

The yeast translation release factors Mrf1p and Sup45p (eRF1) are methylated, respectively, by the methyltransferases Mtq1p and Mtq2p

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3114810

Metabolism and toxicity of arsenic in human urothelial cells expressing rat arsenic (+3 oxidation state)-methyltransferase.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3114810

Inorganic cadmium- and arsenite-induced malignant transformation of human bladder urothelial cells

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3114810

Microbial methylation of metalloids: arsenic, antimony, and bismuth

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3114810

A novel S-adenosyl-L-methionine:arsenic(III) methyltransferase from rat liver cytosol

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3114810

Monomethylarsonous acid (MMA(III)) and arsenite: LD(50) in hamsters and in vitro inhibition of pyruvate dehydrogenase.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3114810

Arsenicals inhibit thioredoxin reductase in cultured rat hepatocytes

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3114810

Determination of monomethylarsonous acid, a key arsenic methylation intermediate, in human urine

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3114810

Arsenic: health effects, mechanisms of actions, and research issues

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3114810

A cell cycle-regulated bacterial DNA methyltransferase is essential for viability

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3114810

The carcinogenicity of arsenic

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3114810

Cancer risks from arsenic in drinking water

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3114810

Genetic polymorphisms in AS3MT and arsenic metabolism in residents of the Red River Delta, Vietnam

8 July 2018

1 reference

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Arsenic metabolism is influenced by polymorphisms in genes involved in one-carbon metabolism and reduction reactions

25 October 2018

1 reference

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Some drinking-water disinfectants and contaminants, including arsenic.

25 October 2018

1 reference

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Methylated trivalent arsenicals as candidate ultimate genotoxic forms of arsenic: Induction of chromosomal mutations but not gene mutations

25 October 2018

1 reference

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DNA damage induced by methylated trivalent arsenicals is mediated by reactive oxygen species

25 October 2018

1 reference

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Plasmid DNA damage caused by methylated arsenicals, ascorbic acid and human liver ferritin

25 October 2018

1 reference

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Undetectable levels of N6-methyl adenine in mouse DNA: Cloning and analysis of PRED28, a gene coding for a putative mammalian DNA adenine methyltransferase

25 October 2018

1 reference

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Comparative toxicity of trivalent and pentavalent inorganic and methylated arsenicals in rat and human cells

25 October 2018

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12 December 2020

Comparative inhibition of yeast glutathione reductase by arsenicals and arsenothiols

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12 December 2020

In vitro methylation of inorganic arsenic in mouse intestinal cecum

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12 December 2020

Methylarsenicals and arsinothiols are potent inhibitors of mouse liver thioredoxin reductase

1 reference

12 December 2020

Identifiers

DOI

10.1289/EHP.1002733

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21193388%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21193388%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

PubMed publication ID

21193388

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