The role of sonic hedgehog-Gli2 pathway in the masculinization of external genitalia (Q35046896)

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1 February 2020

title

The role of sonic hedgehog-Gli2 pathway in the masculinization of external genitalia (English)

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2

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Naomi Nakagata

9

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author name string

Shinichi Miyagawa

1

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Aki Murashima

3

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Akiko Omori

4

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Yoshihiko Satoh

5

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Ryuma Haraguchi

6

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Jun Motoyama

7

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Taisen Iguchi

8

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Chi-Chung Hui

10

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Gen Yamada

11

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language of work or name

English

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publication date

17 May 2011

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volume

152

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issue

7

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page(s)

2894-2903

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Sonic hedgehog controls growth of external genitalia by regulating cell cycle kinetics

1 February 2020

cites work

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Dosage-dependent hedgehog signals integrated with Wnt/beta-catenin signaling regulate external genitalia formation as an appendicular program.

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Multiphasic and tissue-specific roles of sonic hedgehog in cloacal septation and external genitalia development

8 July 2018

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Identification in rats of a programming window for reproductive tract masculinization, disruption of which leads to hypospadias and cryptorchidism

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Mutation of mouse Cyp11a1 promoter caused tissue-specific reduction of gene expression and blunted stress response without affecting reproduction

8 July 2018

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Noggin is required for normal lobe patterning and ductal budding in the mouse prostate

8 July 2018

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Androgen regulation of prostate morphoregulatory gene expression: Fgf10-dependent and -independent pathways

8 July 2018

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Molecular analysis of coordinated bladder and urogenital organ formation by Hedgehog signaling.

8 July 2018

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Molecular genetic cascades for external genitalia formation: an emerging organogenesis program.

8 July 2018

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BMP7 inhibits branching morphogenesis in the prostate gland and interferes with Notch signaling

8 July 2018

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Physiological role for the cochaperone FKBP52 in androgen receptor signaling

8 July 2018

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Androgen mediated regulation and functional implications of fkbp51 expression in prostate cancer

8 July 2018

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Hedgehog signaling and congenital malformations

8 July 2018

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The role of Fgf10 signaling in branching morphogenesis and gene expression of the rat prostate gland: lobe-specific suppression by neonatal estrogens

8 July 2018

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Sonic hedgehog-patched Gli signaling in the developing rat prostate gland: lobe-specific suppression by neonatal estrogens reduces ductal growth and branching

8 July 2018

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Gli2, but not Gli1, is required for initial Shh signaling and ectopic activation of the Shh pathway

8 July 2018

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Sonic hedgehog activates mesenchymal Gli1 expression during prostate ductal bud formation

8 July 2018

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Desert Hedgehog/Patched 1 signaling specifies fetal Leydig cell fate in testis organogenesis

8 July 2018

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8 July 2018

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8 July 2018

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Unique functions of Sonic hedgehog signaling during external genitalia development

8 July 2018

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8 July 2018

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8 July 2018

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Desert hedgehog (Dhh) gene is required in the mouse testis for formation of adult-type Leydig cells and normal development of peritubular cells and seminiferous tubules

8 July 2018

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Sonic hedgehog regulates growth and morphogenesis of the tooth

8 July 2018

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Molecular analysis of external genitalia formation: the role of fibroblast growth factor (Fgf) genes during genital tubercle formation

8 July 2018

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Mouse Gli1 mutants are viable but have defects in SHH signaling in combination with a Gli2 mutation

8 July 2018

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Epithelial-mesenchymal interactions in development of the mouse fetal genital tubercle

8 July 2018

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Prostate development requires Sonic hedgehog expressed by the urogenital sinus epithelium

8 July 2018

1 reference

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Essential function of Gli2 and Gli3 in the formation of lung, trachea and oesophagus

8 July 2018

1 reference

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Interactions between adult human prostatic epithelium and rat urogenital sinus mesenchyme in a tissue recombination model

8 July 2018

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Activating Smoothened mutations in sporadic basal-cell carcinoma

8 July 2018

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Regulation of Cre recombinase activity by mutated estrogen receptor ligand-binding domains

8 July 2018

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Specific and redundant functions of Gli2 and Gli3 zinc finger genes in skeletal patterning and development

8 July 2018

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Cyclopia and defective axial patterning in mice lacking Sonic hedgehog gene function

8 July 2018

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A mouse model of greig cephalopolysyndactyly syndrome: the extra-toesJ mutation contains an intragenic deletion of the Gli3 gene

8 July 2018

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Stromal-epithelial interactions in sex differentiation

8 July 2018

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Role of epithelial-mesenchymal interactions in the differentiation and spatial organization of visceral smooth muscle

8 July 2018

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Lack of defects in androgen production in children with hypospadias

8 July 2018

1 reference

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Anatomical studies of the fibroblast growth factor-10 mutant, Sonic Hedge Hog mutant and androgen receptor mutant mouse genital tubercle

25 October 2018

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Steroid deficiency syndromes in mice with targeted disruption of Cyp11a1.

25 October 2018

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Sonic hedgehog signaling from the urethral epithelium controls external genital development.

25 October 2018

1 reference

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Analysis of FKBP51/FKBP52 chimeras and mutants for Hsp90 binding and association with progesterone receptor complexes

25 October 2018

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12 December 2020

Inhibition of development of both androgen-dependent and androgen-independent pigment cells in scrotal skin dermis of the rat by antiandrogen treatment during fetal growth

1 reference

12 December 2020

Proximal-distal sequence of development of the skeletal tissues in the penis of rat and the inductive effect of epithelium

1 reference

12 December 2020

Gene expression analyses on embryonic external genitalia: identification of regulatory genes possibly involved in masculinization processes

1 reference

12 December 2020

Identifiers

DOI

10.1210/EN.2011-0263

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21586556%20AND%20SRC:MED&resulttype=core&format=json

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1 February 2020

Fatcat ID

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Fatcat

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mapped directly with Wikidata item

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PubMed publication ID

21586556

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