I(f) channel inhibitor ivabradine lowers heart rate in mice with enhanced sympathoadrenergic activities (Q35047088)

6 August 2017

I(f) channel inhibitor ivabradine lowers heart rate in mice with enhanced sympathoadrenergic activities (English)

1 reference

6 August 2017

Anthony M Dart

6

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author name string

Xiao-Jun Du

1

1 reference

6 August 2017

Xinheng Feng

2

1 reference

6 August 2017

Xiao-Ming Gao

3

1 reference

6 August 2017

Tze Ping Tan

4

1 reference

6 August 2017

Helen Kiriazis

5

1 reference

6 August 2017

language of work or name

English

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publication date

5 April 2004

1 reference

British Journal of Pharmacology

6 August 2017

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6 August 2017

142

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6 August 2017

1

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6 August 2017

107-112

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Current-dependent block of rabbit sino-atrial node I(f) channels by ivabradine

6 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1574917

Mechanistic and clinical rationales for using beta-blockers in heart failure.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1574917

Progressive hypertrophy and heart failure in beta1-adrenergic receptor transgenic mice.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1574917

Beta-blocking agents in heart failure. Should they be used and how?

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1574917

Mode of action of bradycardic agent, S 16257, on ionic currents of rabbit sinoatrial node cells

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1574917

The effect of carvedilol on morbidity and mortality in patients with chronic heart failure. U.S. Carvedilol Heart Failure Study Group

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1574917

Electrophysiological effects of S 16257, a novel sino-atrial node modulator, on rabbit and guinea-pig cardiac preparations: comparison with UL-FS 49

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1574917

Physiological effects of inverse agonists in transgenic mice with myocardial overexpression of the beta 2-adrenoceptor

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1574917

Adverse consequences of high sympathetic nervous activity in the failing human heart

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1574917

Acute and chronic cardiac and regional haemodynamic effects of the novel bradycardic agent, S16257, in conscious rats

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1574917

Tachycardia-induced cardiomyopathy: a reversible form of left ventricular dysfunction

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1574917

The contribution of the 'pacemaker' current (if) to generation of spontaneous activity in rabbit sino-atrial node myocytes

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1574917

Abnormalities of peripheral sympathetic nervous system control in congestive heart failure.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1574917

Structure and Modulation of Voltage-Gated Ion Channels

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1574917

Direct activation of cardiac pacemaker channels by intracellular cyclic AMP.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1574917

Dysfunction of the beta- and alpha-adrenergic systems in a model of congestive heart failure. The pacing-overdrive dog.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1574917

Dilated and failing cardiomyopathy in bradykinin B(2) receptor knockout mice.

8 July 2018

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FSJ.BJP.0705696

Electrophysiological Effects of a Single Intravenous Administration of Ivabradine (S 16257) in Adult Patients with Normal Baseline Electrophysiology

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1574917

Antianginal and antiischemic effects of ivabradine, an I(f) inhibitor, in stable angina: a randomized, double-blind, multicentered, placebo-controlled trial

25 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1574917

Differential effects of heart rate reduction and beta-blockade on left ventricular relaxation during exercise

25 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1574917

Effects of heart rate reduction with ivabradine on exercise-induced myocardial ischemia and stunning

25 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1574917

Serial echocardiographic assessment of left ventricular dimensions and function after myocardial infarction in mice.

25 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1574917

Echocardiographic assessment of cardiac function in conscious and anesthetized mice.

25 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1574917

Enhanced myocardial function in transgenic mice overexpressing the beta 2-adrenergic receptor

25 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1574917

Coronary and hemodynamic effects of S 16257, a new bradycardic agent, in resting and exercising conscious dogs.

25 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1574917

Bradycardia and the role of beta-blockade in the amelioration of left ventricular dysfunction

25 October 2018

1 reference

12 December 2020

Early and delayed consequences of beta(2)-adrenergic receptor overexpression in mouse hearts: critical role for expression level

1 reference

12 December 2020

Age-dependent cardiomyopathy and heart failure phenotype in mice overexpressing beta(2)-adrenergic receptors in the heart

1 reference

12 December 2020

Accelerated cardiomyopathy in mice with overexpression of cardiac G(s)alpha and a missense mutation in the alpha-myosin heavy chain

1 reference

12 December 2020

Muscarinic modulation of cardiac rate at low acetylcholine concentrations

1 reference

12 December 2020

I(f) current mediates beta-adrenergic enhancement of heart rate but not contractility in vivo

1 reference

12 December 2020

The pacemaker current (If) plays an important role in regulating SA node pacemaker activity

1 reference

12 December 2020

Response to cardiac sympathetic activation in transgenic mice overexpressing beta 2-adrenergic receptor

1 reference

12 December 2020

Stereospecific in vitro and in vivo effects of the new sinus node inhibitor (+)-S 16257

1 reference

12 December 2020

Determination of ivabradine and its N-demethylated metabolite in human plasma and urine, and in rat and dog plasma by a validated high-performance liquid chromatographic method with fluorescence detection

1 reference

12 December 2020

Identifiers

DOI

10.1038/SJ.BJP.0705696

1 reference

6 August 2017

1 reference

6 August 2017

1 reference