In vitro and in vivo models for assessing drug efflux transporter activity (Q35048743)

6 August 2017

1 reference

title

In vitro and in vivo models for assessing drug efflux transporter activity (English)

1 reference

6 August 2017

Yan Zhang

1

1 reference

6 August 2017

Corbin Bachmeier

series ordinal

2

1 reference

6 August 2017

Donald W Miller

series ordinal

3

1 reference

6 August 2017

language of work or name

English

0 references

publication date

1 January 2003

1 reference

Advanced Drug Delivery Reviews

6 August 2017

published in

1 reference

6 August 2017

volume

55

1 reference

6 August 2017

issue

1

1 reference

6 August 2017

page(s)

31-51

1 reference

Using the national cancer institute anticancer drug screen to assess the effect of MRP expression on drug sensitivity profiles

6 August 2017

cites work

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2802%2900170-9

7 January 2021

The expression of multidrug resistance-associated protein (MRP) in pancreatic adenocarcinoma cell lines

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2802%2900170-9

7 January 2021

Characterization of the ATP-dependent leukotriene C4 export carrier in mastocytoma cells

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2802%2900170-9

7 January 2021

Kinetic and biochemical analysis of carrier-mediated efflux of drugs through the blood-brain and blood-cerebrospinal fluid barriers: importance in the drug delivery to the brain

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2802%2900170-9

7 January 2021

Evaluation of a vincristine resistant Caco-2 cell line for use in a calcein AM extrusion screening assay for P-glycoprotein interaction

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2802%2900170-9

7 January 2021

Multidrug-resistance protein 5 is a multispecific organic anion transporter able to transport nucleotide analogs

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2802%2900170-9

7 January 2021

Loss of ATP-dependent transport activity in pseudoxanthoma elasticum-associated mutants of human ABCC6 (MRP6).

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2802%2900170-9

7 January 2021

Basolateral localization and export activity of the human multidrug resistance-associated protein in polarized pig kidney cells

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2802%2900170-9

7 January 2021

Comparative studies on in vitro methods for evaluating in vivo function of MDR1 P-glycoprotein

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2802%2900170-9

7 January 2021

Astrocytes increase the functional expression of P-glycoprotein in an in vitro model of the blood-brain barrier

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2802%2900170-9

7 January 2021

Pluronic P85 increases permeability of a broad spectrum of drugs in polarized BBMEC and Caco-2 cell monolayers

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2802%2900170-9

7 January 2021

Human MDR1 and mouse mdr1a P-glycoprotein alter the cellular retention and disposition of erythromycin, but not of retinoic acid or benzo(a)pyrene

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2802%2900170-9

7 January 2021

Drug export activity of the human canalicular multispecific organic anion transporter in polarized kidney MDCK cells expressing cMOAT (MRP2) cDNA

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2802%2900170-9

7 January 2021

Canalicular multispecific organic anion transporter/multidrug resistance protein 2 mediates low-affinity transport of reduced glutathione.

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2802%2900170-9

7 January 2021

MRP3, an organic anion transporter able to transport anti-cancer drugs

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2802%2900170-9

7 January 2021

Repacking of the transmembrane domains of P-glycoprotein during the transport ATPase cycle

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2802%2900170-9

7 January 2021

Stimulation of ATPase activity of purified multidrug resistance-associated protein by nucleoside diphosphates

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2802%2900170-9

7 January 2021

Modulation by (iso)flavonoids of the ATPase activity of the multidrug resistance protein

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2802%2900170-9

7 January 2021

A functional assay for detection of the mitoxantrone resistance protein, MXR (ABCG2).

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2802%2900170-9

7 January 2021

In vitro P-glycoprotein affinity for atypical and conventional antipsychotics

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2802%2900170-9

7 January 2021

A high-throughput screening microplate test for the interaction of drugs with P-glycoprotein

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2802%2900170-9

7 January 2021

Interaction of the P-glycoprotein multidrug transporter (MDR1) with high affinity peptide chemosensitizers in isolated membranes, reconstituted systems, and intact cells.

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2802%2900170-9

7 January 2021

ATPase activity of purified multidrug resistance-associated protein

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2802%2900170-9

7 January 2021

Characterization of the ATPase activity of P-glycoprotein from multidrug-resistant Chinese hamster ovary cells

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2802%2900170-9

7 January 2021

Partial purification and reconstitution of the human multidrug-resistance pump: characterization of the drug-stimulatable ATP hydrolysis

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2802%2900170-9

7 January 2021

Competition of hydrophobic peptides, cytotoxic drugs, and chemosensitizers on a common P-glycoprotein pharmacophore as revealed by its ATPase activity

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2802%2900170-9

7 January 2021

Effects of lipids on ATPase activity of purified Chinese hamster P-glycoprotein

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2802%2900170-9

7 January 2021

Interaction of the P-glycoprotein multidrug transporter with peptides and ionophores

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2802%2900170-9

7 January 2021

Drug-stimulated ATPase activity of the human P-glycoprotein

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2802%2900170-9

7 January 2021

Genetic dissection of the function of mammalian P-glycoproteins

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2802%2900170-9

7 January 2021

Disruption of the mouse mdr1a P-glycoprotein gene leads to a deficiency in the blood-brain barrier and to increased sensitivity to drugs

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2802%2900170-9

7 January 2021

Interaction of nonpeptidic delta agonists with P-glycoprotein by in situ mouse brain perfusion: liquid chromatography-mass spectrometry analysis and internal standard strategy

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2802%2900170-9

7 January 2021

Physiologically based pharmacokinetics of digoxin in mdr1a knockout mice.

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2802%2900170-9

7 January 2021

Morphine antinociception is enhanced in mdr1a gene-deficient mice

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2802%2900170-9

7 January 2021

Homozygous disruption of the mdrla P-glycoprotein gene affects blood-nerve barrier function in mice administered with neurotoxic drugs

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2802%2900170-9

7 January 2021

In vitro and in vivo investigations on fluoroquinolones; effects of the P-glycoprotein efflux transporter on brain distribution of sparfloxacin.

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2802%2900170-9

7 January 2021

Penetration of amitriptyline, but not of fluoxetine, into brain is enhanced in mice with blood-brain barrier deficiency due to mdr1a P-glycoprotein gene disruption

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2802%2900170-9

7 January 2021

Role of P-glycoprotein on the CNS disposition of amprenavir (141W94), an HIV protease inhibitor

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2802%2900170-9

7 January 2021

Influence of multidrug resistance (MDR) proteins at the blood-brain barrier on the transport and brain distribution of enaminone anticonvulsants

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2802%2900170-9

7 January 2021

The drug transporter P-glycoprotein limits oral absorption and brain entry of HIV-1 protease inhibitors

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2802%2900170-9

7 January 2021

Limited oral bioavailability and active epithelial excretion of paclitaxel (Taxol) caused by P-glycoprotein in the intestine

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2802%2900170-9

7 January 2021

The role of P-glycoprotein in determining the oral absorption and clearance of the NK2 antagonist, UK-224,671.

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2802%2900170-9

7 January 2021

Active intestinal secretion of new quinolone antimicrobials and the partial contribution of P-glycoprotein

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2802%2900170-9

7 January 2021

Pharmacokinetic role of P-glycoprotein in oral bioavailability and intestinal secretion of grepafloxacin in vivo

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2802%2900170-9

7 January 2021

Substantial excretion of digoxin via the intestinal mucosa and prevention of long-term digoxin accumulation in the brain by the mdr 1a P-glycoprotein

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2802%2900170-9

7 January 2021

Full blockade of intestinal P-glycoprotein and extensive inhibition of blood-brain barrier P-glycoprotein by oral treatment of mice with PSC833

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2802%2900170-9

7 January 2021

Contribution of the murine mdr1a P-glycoprotein to hepatobiliary and intestinal elimination of cationic drugs as measured in mice with an mdr1a gene disruption.

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2802%2900170-9

7 January 2021

Biliary transport of irinotecan and metabolites in normal and P-glycoprotein-deficient mice

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2802%2900170-9

7 January 2021

Opiate-induced analgesia is increased and prolonged in mice lacking P-glycoprotein

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2802%2900170-9

7 January 2021

Transport of opioids from the brain to the periphery by P-glycoprotein: peripheral actions of central drugs

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2802%2900170-9

7 January 2021

Overexpression of glutathione S-transferase II and multidrug resistance transport proteins is associated with acquired tolerance to inorganic arsenic.

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2802%2900170-9

7 January 2021

Differential sensitivities of MRP1-overexpressing lung tumor cells to cytotoxic metals

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2802%2900170-9

7 January 2021

The MRP2/cMOAT transporter and arsenic-glutathione complex formation are required for biliary excretion of arsenic

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2802%2900170-9

7 January 2021

Multidrug-resistance mdr1a/1b double knockout mice are more sensitive than wild type mice to acute arsenic toxicity, with higher arsenic accumulation in tissues

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2802%2900170-9

7 January 2021

Intraepithelial lymphocytes: exploring the Third Way in immunology

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2802%2900170-9

7 January 2021

Altered development of intestinal intraepithelial lymphocytes in P-glycoprotein-deficient mice

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2802%2900170-9

7 January 2021

The multidrug resistance protein family.

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2802%2900170-9

7 January 2021

Characterization of the human multidrug resistance protein isoform MRP3 localized to the basolateral hepatocyte membrane

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2802%2900170-9

7 January 2021

Secretion of organic anions by hepatocytes: involvement of homologues of the multidrug resistance protein.

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2802%2900170-9

7 January 2021

Characterization of the regional intestinal kinetics of drug efflux in rat and human intestine and in Caco-2 cells

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2802%2900170-9

7 January 2021

Tissue and cell distribution of the multidrug resistance-associated protein (MRP) in mouse intestine and kidney

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2802%2900170-9

7 January 2021

MRP8, a new member of ABC transporter superfamily, identified by EST database mining and gene prediction program, is highly expressed in breast cancer

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2802%2900170-9

7 January 2021

MRP9, an unusual truncated member of the ABC transporter superfamily, is highly expressed in breast cancer

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2802%2900170-9

7 January 2021

Toxicological relevance of the multidrug resistance protein 1, MRP1 (ABCC1) and related transporters.

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2802%2900170-9

7 January 2021

Multidrug resistance protein 1 protects the oropharyngeal mucosal layer and the testicular tubules against drug-induced damage

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2802%2900170-9

7 January 2021

Increased sensitivity to anticancer drugs and decreased inflammatory response in mice lacking the multidrug resistance-associated protein

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2802%2900170-9

7 January 2021

Transport of fluorescein in MDCKII-MRP1 transfected cells and mrp1-knockout mice

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2802%2900170-9

7 January 2021

Mrp1 multidrug resistance-associated protein and P-glycoprotein expression in rat brain microvessel endothelial cells.

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2802%2900170-9

7 January 2021

Mechanisms of aflatoxin B1 lung tumorigenesis

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2802%2900170-9

7 January 2021

ATP-dependent transport of aflatoxin B1 and its glutathione conjugates by the product of the multidrug resistance protein (MRP) gene.

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2802%2900170-9

7 January 2021

Role of the multidrug resistance protein 1 gene in the carcinogenicity of aflatoxin B1: investigations using mrp1-null mice

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2802%2900170-9

7 January 2021

Role of the Multidrug Resistance Protein 1 in protection from heavy metal oxyanions: investigations in vitro and in MRP1-deficient mice

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2802%2900170-9

7 January 2021

Identification of a P-glycoprotein-deficient subpopulation in the CF-1 mouse strain using a restriction fragment length polymorphism

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2802%2900170-9

7 January 2021

The subpopulation of CF-1 mice deficient in P-glycoprotein contains a murine retroviral insertion in the mdr1a gene

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2802%2900170-9

7 January 2021

Screening of multidrug-resistance sensitive drugs by in situ brain perfusion in P-glycoprotein-deficient mice

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2802%2900170-9

7 January 2021

Placental P-glycoprotein deficiency enhances susceptibility to chemically induced birth defects in mice

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2802%2900170-9

7 January 2021

Metabolism and disposition of the novel antileukaemic drug, benzamide riboside, in the isolated perfused rat liver

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2802%2900170-9

7 January 2021

Mrp2 is essential for estradiol-17beta(beta-D-glucuronide)-induced cholestasis in rats

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2802%2900170-9

7 January 2021

Mrp2-deficiency in the rat impairs biliary and intestinal excretion and influences metabolism and disposition of the food-derived carcinogen 2-amino-1-methyl-6-phenylimidazo

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2802%2900170-9

7 January 2021

Increased bioavailability of the food-derived carcinogen 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine in MRP2-deficient rats.

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2802%2900170-9

7 January 2021

Normal viability and altered pharmacokinetics in mice lacking mdr1-type (drug-transporting) P-glycoproteins

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2802%2900170-9

7 January 2021

Multidrug resistance protein 1 protects the choroid plexus epithelium and contributes to the blood-cerebrospinal fluid barrier

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2802%2900170-9

7 January 2021

10.1016/S0169-409X(02)00170-9

Identifiers

DOI

1 reference

6 August 2017

1 reference