Adipocyte-specific disruption of fat-specific protein 27 causes hepatosteatosis and insulin resistance in high-fat diet-fed mice. (Q35048863)

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24 February 2020

title

Adipocyte-specific disruption of fat-specific protein 27 causes hepatosteatosis and insulin resistance in high-fat diet-fed mice (English)

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24 February 2020

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4

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24 February 2020

author name string

Naoki Tanaka

1

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24 February 2020

Shogo Takahashi

2

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24 February 2020

Tsutomu Matsubara

3

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24 February 2020

Wataru Sakamoto

5

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24 February 2020

Tatyana Chanturiya

6

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24 February 2020

Ruifeng Teng

7

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24 February 2020

Oksana Gavrilova

8

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24 February 2020

Frank J Gonzalez

9

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24 February 2020

language of work or name

English

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publication date

4 December 2014

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Journal of Biological Chemistry

24 February 2020

published in

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24 February 2020

volume

290

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24 February 2020

issue

5

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page(s)

3092-3105

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Role of white adipose lipolysis in the development of NASH induced by methionine- and choline-deficient diet

24 February 2020

cites work

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Transcriptional activation of Fsp27 by the liver-enriched transcription factor CREBH promotes lipid droplet growth and hepatic steatosis

8 July 2018

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Fat-specific protein 27 (FSP27) interacts with adipose triglyceride lipase (ATGL) to regulate lipolysis and insulin sensitivity in human adipocytes

8 July 2018

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Perilipin1 promotes unilocular lipid droplet formation through the activation of Fsp27 in adipocytes

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Disruption of hypoxia-inducible factor 1 in adipocytes improves insulin sensitivity and decreases adiposity in high-fat diet-fed mice

8 July 2018

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Clinical review#: Lipodystrophies: genetic and acquired body fat disorders

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Partial lipodystrophy and insulin resistant diabetes in a patient with a homozygous nonsense mutation in CIDEC

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Molecular mechanisms of hepatic steatosis and insulin resistance in the AGPAT2-deficient mouse model of congenital generalized lipodystrophy

8 July 2018

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Up-regulation of mitochondrial activity and acquirement of brown adipose tissue-like property in the white adipose tissue of fsp27 deficient mice

8 July 2018

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FSP27 contributes to efficient energy storage in murine white adipocytes by promoting the formation of unilocular lipid droplets

8 July 2018

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Lipid droplets: FSP27 knockout enhances their sizzle

8 July 2018

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Cidea is associated with lipid droplets and insulin sensitivity in humans

8 July 2018

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Hepatic steatosis in leptin-deficient mice is promoted by the PPARgamma target gene Fsp27.

8 July 2018

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Fat-specific protein 27 regulates storage of triacylglycerol

8 July 2018

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Assessment of fat-specific protein 27 in the adipocyte lineage suggests a dual role for FSP27 in adipocyte metabolism and cell death

8 July 2018

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PPARalpha activation is essential for HCV core protein-induced hepatic steatosis and hepatocellular carcinoma in mice

8 July 2018

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Fat-specific protein 27, a novel lipid droplet protein that enhances triglyceride storage

8 July 2018

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8 July 2018

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FOXC2 is a winged helix gene that counteracts obesity, hypertriglyceridemia, and diet-induced insulin resistance

8 July 2018

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Adipose-selective targeting of the GLUT4 gene impairs insulin action in muscle and liver

8 July 2018

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Utility of C57BL/6J x 129/SvJae embryonic stem cells for generating chromosomal deletions: tolerance to gamma radiation and microsatellite polymorphism

8 July 2018

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Liver peroxisome proliferator-activated receptor gamma contributes to hepatic steatosis, triglyceride clearance, and regulation of body fat mass.

8 July 2018

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Crossref

https://api.crossref.org/works/10.1074%2FJBC.M114.605980

Seipin ablation in mice results in severe generalized lipodystrophy.

21 January 2018

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Crossref

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21 January 2018

Identifiers

DOI

10.1074/JBC.M114.605980

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25477509%20AND%20SRC:MED&resulttype=core&format=json

24 February 2020

1 reference

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24 February 2020

PubMed publication ID

25477509

1 reference