Connective tissue growth factor: an attractive therapeutic target in fibrotic renal disease (Q35050392)

6 August 2017

Connective tissue growth factor: an attractive therapeutic target in fibrotic renal disease (English)

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ORCID Public Data File 2021

6 August 2017

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author name string

John KG Crean

1

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6 August 2017

DWP Lappin

2

1 reference

6 August 2017

C Godson

3

1 reference

6 August 2017

Hugh R Brady

4

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6 August 2017

language of work or name

English

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publication date

1 August 2001

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Expert Opinion on Therapeutic Targets

6 August 2017

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6 August 2017

5

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6 August 2017

4

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6 August 2017

519-530

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Transforming growth factor beta in tissue fibrosis

6 August 2017

1 reference

https://api.crossref.org/works/10.1517%2F14728222.5.4.519

Connective tissue growth factor: potential role in glomerulosclerosis and tubulointerstitial fibrosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.5.4.519

Suppression subtractive hybridization identifies high glucose levels as a stimulus for expression of connective tissue growth factor and other genes in human mesangial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.5.4.519

Hyperglycemia and diabetic kidney disease. The case for transforming growth factor-beta as a key mediator

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.5.4.519

Role of transforming growth factor beta in human disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.5.4.519

Production of extracellular matrix by glomerular epithelial cells is regulated by transforming growth factor-beta 1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.5.4.519

Identification and characterization of a fibroblast marker: FSP1

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.5.4.519

Regulation of immune responses by TGF-beta

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.5.4.519

Targeted disruption of the mouse transforming growth factor-beta 1 gene results in multifocal inflammatory disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.5.4.519

Connective tissue growth factor: a cysteine-rich mitogen secreted by human vascular endothelial cells is related to the SRC-induced immediate early gene product CEF-10

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.5.4.519

Cloning the full-length cDNA for rat connective tissue growth factor: implications for skeletal development.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.5.4.519

Molecular cloning of genes differentially regulated by TNF-alpha in bovine aortic endothelial cells, fibroblasts and smooth muscle cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.5.4.519

The modular architecture of a new family of growth regulators related to connective tissue growth factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.5.4.519

Transcriptional activation by TGF beta 1 mediated by the dyad symmetry element (DSE) and the TPA responsive element (TRE).

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.5.4.519

Identification of human ccn2 (connective tissue growth factor) promoter polymorphisms

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.5.4.519

Involvement of cis-acting repressive element(s) in the 3'-untranslated region of human connective tissue growth factor gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.5.4.519

Identification of connective tissue growth factor as a target of WT1 transcriptional regulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.5.4.519

Des-Arg(10)-kallidin engagement of the B1 receptor stimulates type I collagen synthesis via stabilization of connective tissue growth factor mRNA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.5.4.519

Factor VIIa and thrombin induce the expression of Cyr61 and connective tissue growth factor, extracellular matrix signaling proteins that could act as possible downstream mediators in factor VIIa x tissue factor-induced signal transduction

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.5.4.519

Thrombin is a potent inducer of connective tissue growth factor production via proteolytic activation of protease-activated receptor-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.5.4.519

Tumor necrosis factor alpha suppresses the induction of connective tissue growth factor by transforming growth factor-beta in normal and scleroderma fibroblasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.5.4.519

Connective tissue growth factor induces apoptosis in human breast cancer cell line MCF-7.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.5.4.519

In vitro evidence for differential involvement of CTGF, TGFbeta, and PDGF-BB in mesangial response to injury

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.5.4.519

Cyr61 and Fisp12 are both ECM-associated signaling molecules: activities, metabolism, and localization during development

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.5.4.519

Effects of CTGF/Hcs24, a hypertrophic chondrocyte-specific gene product, on the proliferation and differentiation of osteoblastic cells in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.5.4.519

The CCN family of angiogenic regulators: the integrin connection

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.5.4.519

The angiogenic factors Cyr61 and connective tissue growth factor induce adhesive signaling in primary human skin fibroblasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.5.4.519

CTGF expression is induced by TGF- beta in cardiac fibroblasts and cardiac myocytes: a potential role in heart fibrosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.5.4.519

Expression of connective tissue growth factor in experimental rat and human liver fibrosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.5.4.519

Significant correlation between connective tissue growth factor gene expression and skin sclerosis in tissue sections from patients with systemic sclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.5.4.519

Increased expression of connective tissue growth factor in fibrotic human liver and in activated hepatic stellate cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.5.4.519

Induction of connective tissue growth factor by activation of heptahelical receptors. Modulation by Rho proteins and the actin cytoskeleton

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.5.4.519

Suppression of experimental glomerulonephritis by antiserum against transforming growth factor β1

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.5.4.519

21 January 2018

Identifiers

DOI

10.1517/14728222.5.4.519

1 reference

6 August 2017

1 reference