Experimental autoimmune encephalomyelitis: cytokines, effector T cells, and antigen-presenting cells in a prototypical Th1-mediated autoimmune disease (Q35051201)

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English	Experimental autoimmune encephalomyelitis: cytokines, effector T cells, and antigen-presenting cells in a prototypical Th1-mediated autoimmune disease	scientific article

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

6 August 2017

1 reference

Europe PubMed Central

Experimental autoimmune encephalomyelitis: cytokines, effector T cells, and antigen-presenting cells in a prototypical Th1-mediated autoimmune disease (English)

1 reference

Europe PubMed Central

PubMed publication ID

6 August 2017

experimental autoimmune encephalomyelitis

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autoimmune disease

1 reference

based on heuristic

inferred from title

author name string

Benjamin M Segal

1

1 reference

Europe PubMed Central

PubMed publication ID

6 August 2017

publication date

1 January 2003

1 reference

Europe PubMed Central

PubMed publication ID

6 August 2017

Current Allergy and Asthma Reports

1 reference

Europe PubMed Central

PubMed publication ID

6 August 2017

3

1 reference

Europe PubMed Central

PubMed publication ID

6 August 2017

1

1 reference

Europe PubMed Central

PubMed publication ID

6 August 2017

86-93

1 reference

Europe PubMed Central

PubMed publication ID

6 August 2017

IFN-gamma shapes immune invasion of the central nervous system via regulation of chemokines.

1 reference

https://api.crossref.org/works/10.1007%2FS11882-003-0017-6

21 January 2018

De novo central nervous system processing of myelin antigen is required for the initiation of experimental autoimmune encephalomyelitis.

1 reference

https://api.crossref.org/works/10.1007%2FS11882-003-0017-6

21 January 2018

Immunostimulatory CpG-DNA activates murine microglia

1 reference

https://api.crossref.org/works/10.1007%2FS11882-003-0017-6

21 January 2018

Brain dendritic cells and macrophages/microglia in central nervous system inflammation

1 reference

https://api.crossref.org/works/10.1007%2FS11882-003-0017-6

21 January 2018

Intracerebral recruitment and maturation of dendritic cells in the onset and progression of experimental autoimmune encephalomyelitis

1 reference

https://api.crossref.org/works/10.1007%2FS11882-003-0017-6

21 January 2018

Multiple sclerosis flares associated with recombinant granulocyte colony-stimulating factor

1 reference

https://api.crossref.org/works/10.1007%2FS11882-003-0017-6

21 January 2018

Tumor necrosis factor blockade in actively induced experimental autoimmune encephalomyelitis prevents clinical disease despite activated T cell infiltration to the central nervous system

1 reference

https://pubmed.ncbi.nlm.nih.gov/12543000

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Dendritic cells and differential usage of the MHC class II transactivator promoters in the central nervous system in experimental autoimmune encephalitis

1 reference

https://pubmed.ncbi.nlm.nih.gov/12543000

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Role of CD8+ T cells in murine experimental allergic encephalomyelitis

1 reference

https://pubmed.ncbi.nlm.nih.gov/12543000

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

IL-12 unmasks latent autoimmune disease in resistant mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/12543000

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Macrophage populations associated with multiple sclerosis plaques

1 reference

https://pubmed.ncbi.nlm.nih.gov/12543000

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Experimental autoimmune encephalitis and inflammation in the absence of interleukin-12

1 reference

https://pubmed.ncbi.nlm.nih.gov/12543000

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Regulation of IL-12 receptor expression in early T-helper responses implies two phases of Th1 differentiation: capacitance and development.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12543000

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Microglia are more efficient than astrocytes in antigen processing and in Th1 but not Th2 cell activation.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12543000

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Regulatory circuits in autoimmunity: recruitment of counter-regulatory CD8+ T cells by encephalitogenic CD4+ T line cells.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12543000

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Class II HLA-DC beta-chain DNA restriction fragments differentiate among HLA-DR2 individuals in insulin-dependent diabetes and multiple sclerosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/12543000

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Interferon-gamma confers resistance to experimental allergic encephalomyelitis.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12543000

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Developmental plasticity of CNS microglia

1 reference

https://pubmed.ncbi.nlm.nih.gov/12543000

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The rapid isolation of clonable antigen-specific T lymphocyte lines capable of mediating autoimmune encephalomyelitis

1 reference

https://pubmed.ncbi.nlm.nih.gov/12543000

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Analysis of cytokine mRNA expression in the central nervous system of mice with experimental autoimmune encephalomyelitis reveals that IL-10 mRNA expression correlates with recovery

1 reference

https://pubmed.ncbi.nlm.nih.gov/12543000

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Failure to suppress the expansion of the activated CD4 T cell population in interferon gamma-deficient mice leads to exacerbation of experimental autoimmune encephalomyelitis

1 reference

https://pubmed.ncbi.nlm.nih.gov/12543000

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cytokines in relapsing experimental autoimmune encephalomyelitis in DA rats: persistent mRNA expression of proinflammatory cytokines and absent expression of interleukin-10 and transforming growth factor-beta

1 reference

https://pubmed.ncbi.nlm.nih.gov/12543000

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Help for cytotoxic-T-cell responses is mediated by CD40 signalling

1 reference

https://pubmed.ncbi.nlm.nih.gov/12543000

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

HLA associations in multiple sclerosis: implications for immunopathogenesis

1 reference

https://pubmed.ncbi.nlm.nih.gov/12543000

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Monoclonal anti-gamma interferon antibodies enhance experimental allergic encephalomyelitis

1 reference

https://pubmed.ncbi.nlm.nih.gov/12543000

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Reversal of experimental allergic encephalomyelitis with monoclonal antibody to a T-cell subset marker

1 reference

https://pubmed.ncbi.nlm.nih.gov/12543000

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neuroantigen-specific Th2 cells are inefficient suppressors of experimental autoimmune encephalomyelitis induced by effector Th1 cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/12543000

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Immune regulation in self tolerance: functional elimination of a self-reactive, counterregulatory CD8+ T lymphocyte circuit by neonatal transfer of encephalitogenic CD4+ T cells lines

1 reference

https://pubmed.ncbi.nlm.nih.gov/12543000

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

An antibody to lymphotoxin and tumor necrosis factor prevents transfer of experimental allergic encephalomyelitis

1 reference

https://pubmed.ncbi.nlm.nih.gov/12543000

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Suppression of experimental autoimmune encephalomyelitis with a TNF binding protein (TNFbp) correlates with down-regulation of VCAM-1/VLA-4.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12543000

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Acute autoimmune encephalomyelitis in mice. II. Susceptibility is controlled by the combination of H-2 and histamine sensitization genes

1 reference

https://pubmed.ncbi.nlm.nih.gov/12543000

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cellular immune response in multiple sclerosis plaques

1 reference

https://pubmed.ncbi.nlm.nih.gov/12543000

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Tumor necrosis factor alpha and lymphotoxin alpha are not required for induction of acute experimental autoimmune encephalomyelitis.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12543000

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mice with a disrupted IFN-gamma gene are susceptible to the induction of experimental autoimmune encephalomyelitis (EAE).

1 reference

https://pubmed.ncbi.nlm.nih.gov/12543000

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Lymphotoxin and tumor necrosis factor-alpha production by myelin basic protein-specific T cell clones correlates with encephalitogenicity

1 reference

https://pubmed.ncbi.nlm.nih.gov/12543000

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

An interleukin (IL)-10/IL-12 immunoregulatory circuit controls susceptibility to autoimmune disease.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12543000

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The involvement of T cell receptor peptide-specific regulatory CD4+ T cells in recovery from antigen-induced autoimmune disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/12543000

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The role of IL-12 in the induction of organ-specific autoimmune diseases

1 reference

https://pubmed.ncbi.nlm.nih.gov/12543000

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Enhancement of experimental allergic encephalomyelitis in mice by antibodies against IFN-gamma

1 reference

https://pubmed.ncbi.nlm.nih.gov/12543000

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Phenotype and functions of brain dendritic cells emerging during chronic infection of mice with Toxoplasma gondii

1 reference

https://pubmed.ncbi.nlm.nih.gov/12543000

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Granulocyte macrophage colony-stimulating factor: a new putative therapeutic target in multiple sclerosis.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12543000

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A pathogenic role for myelin-specific CD8(+) T cells in a model for multiple sclerosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/12543000

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

IFN-gamma plays a critical down-regulatory role in the induction and effector phase of myelin oligodendrocyte glycoprotein-induced autoimmune encephalomyelitis

1 reference

https://pubmed.ncbi.nlm.nih.gov/12543000

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

An altered peptide ligand mediates immune deviation and prevents autoimmune encephalomyelitis

1 reference

https://pubmed.ncbi.nlm.nih.gov/12543000

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Prevention of experimental autoimmune encephalomyelitis by antibodies against interleukin 12.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12543000

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Less mortality but more relapses in experimental allergic encephalomyelitis in CD8-/- mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/12543000

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Expression of costimulatory molecules B7-1 (CD80), B7-2 (CD86), and interleukin 12 cytokine in multiple sclerosis lesions

1 reference

https://pubmed.ncbi.nlm.nih.gov/12543000

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Determinant spreading and the dynamics of the autoimmune T-cell repertoire.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12543000

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Adoptive transfer of experimental allergic encephalomyelitis in SJL/J mice after in vitro activation of lymph node cells by myelin basic protein: requirement for Lyt 1+ 2- T lymphocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/12543000

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cytokines and murine autoimmune encephalomyelitis: inhibition or enhancement of disease with antibodies to select cytokines, or by delivery of exogenous cytokines using a recombinant vaccinia virus system

1 reference

https://pubmed.ncbi.nlm.nih.gov/12543000

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

TNF is a potent anti-inflammatory cytokine in autoimmune-mediated demyelination.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12543000

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Decreased interleukin-10 and increased interleukin-12p40 mRNA are associated with disease activity and characterize different disease stages in multiple sclerosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/12543000

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Elevated interleukin-12 in progressive multiple sclerosis correlates with disease activity and is normalized by pulse cyclophosphamide therapy

1 reference

https://pubmed.ncbi.nlm.nih.gov/12543000

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mice with an inactivation of the inducible nitric oxide synthase gene are susceptible to experimental autoimmune encephalomyelitis

1 reference

https://pubmed.ncbi.nlm.nih.gov/12543000

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Novel p19 protein engages IL-12p40 to form a cytokine, IL-23, with biological activities similar as well as distinct from IL-12

1 reference

https://pubmed.ncbi.nlm.nih.gov/12543000

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Chronic relapsing experimental autoimmune encephalomyelitis (CREAE) in mice: enhancement by monoclonal antibodies against interferon-gamma

1 reference

https://pubmed.ncbi.nlm.nih.gov/12543000

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effect of anti-interferon-gamma monoclonal antibody treatment on the development of experimental allergic encephalomyelitis in resistant mouse strains.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12543000

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Encephalitogenic T cells in the B10.PL model of experimental allergic encephalomyelitis (EAE) are of the Th-1 lymphokine subtype

1 reference

https://pubmed.ncbi.nlm.nih.gov/12543000

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Suppression of experimentally induced autoimmune encephalomyelitis by cytolytic T-T cell interactions.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12543000

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Requirement for endocytic antigen processing and influence of invariant chain and H-2M deficiencies in CNS autoimmunity

1 reference

https://pubmed.ncbi.nlm.nih.gov/12543000

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Specificity requirements for selection and effector functions of CD25+4+ regulatory T cells in anti-myelin basic protein T cell receptor transgenic mice.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12543000

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Induction of a type 1 regulatory CD4 T cell response following V beta 8.2 DNA vaccination results in immune deviation and protection from experimental autoimmune encephalomyelitis

1 reference

https://pubmed.ncbi.nlm.nih.gov/12543000

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effect of interferon-γ on myelin basic protein-specific T cell line proliferation in response to antigen-pulsed accessory cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/12543000

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Clonal expansions of CD8(+) T cells dominate the T cell infiltrate in active multiple sclerosis lesions as shown by micromanipulation and single cell polymerase chain reaction

1 reference

https://pubmed.ncbi.nlm.nih.gov/12543000

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cytokine production in the central nervous system of Lewis rats with experimental autoimmune encephalomyelitis: dynamics of mRNA expression for interleukin-10, interleukin-12, cytolysin, tumor necrosis factor α and tumor necrosis factor β

1 reference

https://pubmed.ncbi.nlm.nih.gov/12543000

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Myelin antigen-specific CD8+ T cells are encephalitogenic and produce severe disease in C57BL/6 mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/12543000

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Presentation of proteolipid protein epitopes and B7-1-dependent activation of encephalitogenic T cells by IFN-gamma-activated SJL/J astrocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/12543000

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

CD40 engagement stimulates IL-12 p70 production by human microglial cells: basis for Th1 polarization in the CNS

1 reference

https://pubmed.ncbi.nlm.nih.gov/12543000

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Encephalitogenic potential of the myelin basic protein peptide (amino acids 83-99) in multiple sclerosis: results of a phase II clinical trial with an altered peptide ligand

1 reference

https://pubmed.ncbi.nlm.nih.gov/12543000

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Prevention of chronic relapsing experimental autoimmune encephalomyelitis by soluble tumor necrosis factor receptor I

1 reference

https://pubmed.ncbi.nlm.nih.gov/12543000

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1007/S11882-003-0017-6

1 reference

Europe PubMed Central

PubMed publication ID

6 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

6 August 2017

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