A central role for peripheral dendritic cells in the induction of acquired thymic tolerance (Q35053394)

6 August 2017

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title

A central role for peripheral dendritic cells in the induction of acquired thymic tolerance (English)

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central tolerance induction to nonself antigen

6 August 2017

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Gene Ontology release 2020-05-02

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Irving Goldschneider

1

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PubMed ID

12547504

6 August 2017

Robert E Cone

series ordinal

2

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6 August 2017

1 February 2003

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6 August 2017

5

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inferred from page(s)

published in

Trends in Immunology

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6 August 2017

24

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6 August 2017

2

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6 August 2017

77-81

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How do monoclonal antibodies induce tolerance? A role for infectious tolerance?

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Avoiding horror autotoxicus: the importance of dendritic cells in peripheral T cell tolerance

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Promiscuous gene expression and central T-cell tolerance: more than meets the eye.

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Projection of an immunological self shadow within the thymus by the aire protein

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Reentry of T cells to the adult thymus is restricted to activated T cells

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Three day neonatal thymectomy selectively depletes NK1.1+ T cells

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The third function of the thymus.

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Thymus and tolerance. Is regulation the major function of the thymus?

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Immunologic tolerance maintained by CD25+ CD4+ regulatory T cells: their common role in controlling autoimmunity, tumor immunity, and transplantation tolerance

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Mouse CD1-specific NK1 T cells: development, specificity, and function

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NKT cells: facts, functions and fallacies.

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Control of T-cell activation by CD4+ CD25+ suppressor T cells

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A model for developmentally acquired thymus-dependent tolerance to central and peripheral antigens

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A natural killer T (NKT) cell developmental pathway iInvolving a thymus-dependent NK1.1(-)CD4(+) CD1d-dependent precursor stage

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Tolerance to cyclosporin A-induced autologous graft-versus-host disease is mediated by a CD4+CD25+ subset of recent thymic emigrants

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On the ontogeny and physiology of regulatory T cells

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The failure of intrathymic transplantation of nonimmunogenic islet allografts to promote induction of donor-specific unresponsiveness

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Prevention of diabetes in nonobese diabetic mice by dendritic cell transfer

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Induction of peripheral tolerance by intrathymic inoculation of soluble alloantigens: evidence for the role of host antigen-presenting cells and suppressor cell mechanism

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Mechanisms of acquired thymic tolerance in experimental autoimmune encephalomyelitis: thymic dendritic-enriched cells induce specific peripheral T cell unresponsiveness in vivo

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Studies on the induction of anterior chamber-associated immune deviation (ACAID). III. Induction of ACAID depends upon intraocular transforming growth factor-beta

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7 January 2021

CD1-reactive natural killer T cells are required for development of systemic tolerance through an immune-privileged site.

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MIP-2 recruits NKT cells to the spleen during tolerance induction

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Role for thymic and splenic regulatory CD4+ T cells induced by donor dendritic cells in allograft tolerance by LF15-0195 treatment

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Phenotype, localization, and mechanism of suppression of CD4(+)CD25(+) human thymocytes

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Immature, semi-mature and fully mature dendritic cells: which signals induce tolerance or immunity?

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Notch1 deficiency dissociates the intrathymic development of dendritic cells and T cells.

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Developmental dissociation of thymic dendritic cell and thymocyte lineages revealed in growth factor receptor mutant mice

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RelB is essential for the development of myeloid-related CD8alpha- dendritic cells but not of lymphoid-related CD8alpha+ dendritic cells

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Id2 and Id3 inhibit development of CD34(+) stem cells into predendritic cell (pre-DC)2 but not into pre-DC1. Evidence for a lymphoid origin of pre-DC2.

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The importation of hematogenous precursors by the thymus is a gated phenomenon in normal adult mice

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Functional demonstration of intrathymic binding sites and microvascular gates for prothymocytes in irradiated mice

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Targeted expression of major histocompatibility complex (MHC) class II molecules demonstrates that dendritic cells can induce negative but not positive selection of thymocytes in vivo

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7 January 2021

Human thymus contains 2 distinct dendritic cell populations

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Human thymus contains IFN-alpha-producing CD11c(-), myeloid CD11c(+), and mature interdigitating dendritic cells

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Identification of a myeloid intrathymic pathway of dendritic cell development marked by expression of the granulocyte macrophage-colony-stimulating factor receptor.

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Pathogen-specific regulatory T cells provoke a shift in the Th1/Th2 paradigm in immunity to infectious diseases

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Neural control of ocular immune privilege.

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In situ tolerance within the central nervous system as a mechanism for preventing autoimmunity

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Regulatory cells generated by testicular tolerization to retinal S-antigen: possible involvement of IL-4, IL-10, and TGF-beta in the suppression of experimental autoimmune uveoretinitis

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The immunology of pregnancy

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Myelin basic protein infused into cerebrospinal fluid suppresses experimental autoimmune encephalomyelitis

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Thymic recognition of class II major histocompatibility complex allopeptides induces donor-specific unresponsiveness to renal allografts

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Role of the thymus in transplantation tolerance in miniature swine. I. Requirement of the thymus for rapid and stable induction of tolerance to class I-mismatched renal allografts

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Dendritic cells as a tool to induce anergic and regulatory T cells

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Identifiers

DOI

1 reference

6 August 2017

1 reference

PubMed ID

12547504