Structure and mechanism of the diterpene cyclase ent-copalyl diphosphate synthase (Q35056352)

6 August 2017

Structure and mechanism of the diterpene cyclase ent-copalyl diphosphate synthase (English)

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6 August 2017

Huayou Hu

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Reuben J. Peters

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Reuben J Peters

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author name string

Mustafa Köksal

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6 August 2017

Robert M Coates

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6 August 2017

David W Christianson

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6 August 2017

22 May 2011

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6 August 2017

Nature Chemical Biology

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6 August 2017

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6 August 2017

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6 August 2017

431-433

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https://scigraph.springernature.com/pub.10.1038/nchembio.578

6 August 2017

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cites work

Taxadiene synthase structure and evolution of modular architecture in terpene biosynthesis

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Diterpene cyclases and the nature of the isoprene fold

8 July 2018

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Unearthing the roots of the terpenome

8 July 2018

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The function of terpene natural products in the natural world

8 July 2018

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Structural biology and chemistry of the terpenoid cyclases

8 July 2018

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Terpene synthases and the regulation, diversity and biological roles of terpene metabolism

8 July 2018

1 reference

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Conversion of squalene to the pentacarbocyclic hopene

8 July 2018

1 reference

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Bornyl diphosphate synthase: structure and strategy for carbocation manipulation by a terpenoid cyclase

8 July 2018

1 reference

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Structure of trichodiene synthase from Fusarium sporotrichioides provides mechanistic inferences on the terpene cyclization cascade

8 July 2018

1 reference

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The structure of the membrane protein squalene-hopene cyclase at 2.0 A resolution

8 July 2018

1 reference

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Isoprenoid biosynthesis: manifold chemistry catalyzed by similar enzymes

8 July 2018

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Crystal structure of pentalenene synthase: mechanistic insights on terpenoid cyclization reactions in biology

8 July 2018

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Structural basis for cyclic terpene biosynthesis by tobacco 5-epi-aristolochene synthase

8 July 2018

1 reference

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Structure and function of a squalene cyclase

8 July 2018

1 reference

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Crystal structure of recombinant farnesyl diphosphate synthase at 2.6-A resolution

8 July 2018

1 reference

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The Arabidopsis GA1 locus encodes the cyclase ent-kaurene synthetase A of gibberellin biosynthesis

8 July 2018

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8 July 2018

Terpenoid biomaterials

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FNCHEMBIO.578

Insight into steroid scaffold formation from the structure of human oxidosqualene cyclase

21 January 2018

1 reference

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https://api.crossref.org/works/10.1038%2FNCHEMBIO.578

Methodology for the Preparation of Pure RecombinantS. cerevisiaeLanosterol Synthase Using a Baculovirus Expression System. Evidence That Oxirane Cleavage and A-Ring Formation Are Concerted in the Biosynthesis of Lanosterol from 2,3-Oxidosqualene

21 January 2018

1 reference

Crossref

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Enzyme Mechanisms for Polycyclic Triterpene Formation

21 January 2018

1 reference

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Probing the Role of the DXDD Motif in Class II Diterpene Cyclases

25 October 2018

1 reference

12 December 2020

Functional analysis of the DXDDTA motif in squalene-hopene cyclase by site-directed mutagenesis experiments: initiation site of the polycyclization reaction and stabilization site of the carbocation intermediate of the initially cyclized A-ring

1 reference

12 December 2020

Synergistic substrate inhibition of ent-copalyl diphosphate synthase: a potential feed-forward inhibition mechanism limiting gibberellin metabolism

1 reference

12 December 2020

Properties of purified squalene-hopene cyclase from Bacillus acidocaldarius

1 reference

12 December 2020

Identifiers

DOI

10.1038/NCHEMBIO.578

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Dimensions Publication ID

6 August 2017

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6 August 2017

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