Antimicrobial peptides: current status and therapeutic potential (Q35056723)

6 August 2017

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title

Antimicrobial peptides: current status and therapeutic potential (English)

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6 August 2017

antimicrobial peptide

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inferred from title

author

Andreas Rembert Koczulla

series ordinal

1

object named as

Andreas R Koczulla

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6 August 2017

Robert Bals

2

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6 August 2017

1 January 2003

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6 August 2017

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6 August 2017

63

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6 August 2017

4

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6 August 2017

389-406

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https://scigraph.springernature.com/pub.10.2165/00003495-200363040-00005

6 August 2017

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Evaluation of the effects of peptide antibiotics human beta-defensins-1/-2 and LL-37 on histamine release and prostaglandin D(2) production from mast cells

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Primary structures of three human neutrophil defensins

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Mechanism of alamethicin insertion into lipid bilayers

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Membrane Thinning Effect of the β-Sheet Antimicrobial Protegrin†

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Human cathelicidin, hCAP-18, is processed to the antimicrobial peptide LL-37 by extracellular cleavage with proteinase 3

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Engineered salt-insensitive alpha-defensins with end-to-end circularized structures.

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Animal antimicrobial peptides: an overview

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The imd gene is required for local Cecropin expression in Drosophila barrier epithelia

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Potassium release, a useful tool for studying antimicrobial peptides

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An anionic antimicrobial peptide from toad Bombina maxima

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Modulation of Neisseria gonorrhoeae susceptibility to vertebrate antibacterial peptides due to a member of the resistance/nodulation/division efflux pump family

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12 December 2020

Defensins. Natural peptide antibiotics of human neutrophils

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12 December 2020

Amphipathic, alpha-helical antimicrobial peptides

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12 December 2020

Purification and characterization of a plant antimicrobial peptide expressed in Escherichia coli

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12 December 2020

A peptide antibiotic from human skin

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Radiolabelled antimicrobial peptides for imaging of infections: a review

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12 December 2020

Identification and characterization of novel antimicrobial decapeptides generated by combinatorial chemistry

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12 December 2020

Inactivation of the dlt operon in Staphylococcus aureus confers sensitivity to defensins, protegrins, and other antimicrobial peptides

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12 December 2020

The multiple carrier model of nonribosomal peptide biosynthesis at modular multienzymatic templates

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12 December 2020

Recombinant DNA procedures for producing small antimicrobial cationic peptides in bacteria.

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12 December 2020

Applications of the bacteriocin, nisin

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12 December 2020

Human neutrophil defensins selectively chemoattract naive T and immature dendritic cells

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12 December 2020

Dermcidin: a novel human antibiotic peptide secreted by sweat glands

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12 December 2020

Isolation and characterization of human beta -defensin-3, a novel human inducible peptide antibiotic

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12 December 2020

Towards a rational development of anti-endotoxin agents: novel approaches to sequestration of bacterial endotoxins with small molecules

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12 December 2020

Cathelicidins: a novel protein family with a common proregion and a variable C-terminal antimicrobial domain

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12 December 2020

Rapid identification of compounds with enhanced antimicrobial activity by using conformationally defined combinatorial libraries

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12 December 2020

Specific binding of nisin to the peptidoglycan precursor lipid II combines pore formation and inhibition of cell wall biosynthesis for potent antibiotic activity

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12 December 2020

Effect of defensins on interleukin-8 synthesis in airway epithelial cells

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12 December 2020

Regulation of human beta-defensin-2 in gingival epithelial cells: the involvement of mitogen-activated protein kinase pathways, but not the NF-kappaB transcription factor family

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12 December 2020

Designer assays for antimicrobial peptides. Disputing the "one-size-fits-all" theory

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12 December 2020

Antibacterial components in bronchoalveolar lavage fluid from healthy individuals and sarcoidosis patients

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12 December 2020

Mechanisms for induction of acquired host immunity by neutrophil peptide defensins

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12 December 2020

Cathelicidins: a family of endogenous antimicrobial peptides

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12 December 2020

99mTc-labeled antimicrobial peptides for detection of bacterial and Candida albicans infections.

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12 December 2020

Bacterial phosphorylcholine decreases susceptibility to the antimicrobial peptide LL-37/hCAP18 expressed in the upper respiratory tract.

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12 December 2020

The antimicrobial peptide trichogin and its interaction with phospholipid membranes

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12 December 2020

Structure-activity relationship study: short antimicrobial peptides

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12 December 2020

Specific lipopolysaccharide found in cystic fibrosis airway Pseudomonas aeruginosa

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12 December 2020

Technetium-99m labelled antimicrobial peptides discriminate between bacterial infections and sterile inflammations

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12 December 2020

Polymyxin B sulfate and colistin: old antibiotics for emerging multiresistant gram-negative bacteria

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12 December 2020

Antiendotoxin activity of cationic peptide antimicrobial agents

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12 December 2020

FALL-39, a putative human peptide antibiotic, is cysteine-free and expressed in bone marrow and testis

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12 December 2020

Circular minidefensins and posttranslational generation of molecular diversity

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12 December 2020

Identification of human beta-defensin-2 in respiratory tract and plasma and its increase in bacterial pneumonia

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12 December 2020

Signaling mechanisms in the antimicrobial host defense of Drosophila

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12 December 2020

Regulation of intestinal alpha-defensin activation by the metalloproteinase matrilysin in innate host defense

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12 December 2020

Design and synthesis of novel antimicrobial pseudopeptides with selective membrane-perturbation activity

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12 December 2020

Potential therapeutic applications of magainins and other antimicrobial agents of animal origin

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12 December 2020

A mosaic analysis in Drosophila fat body cells of the control of antimicrobial peptide genes by the Rel proteins Dorsal and DIF.

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12 December 2020

Antimicrobial peptides of multicellular organisms

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12 December 2020

Identification of defensin-1, defensin-2, and CAP37/azurocidin as T-cell chemoattractant proteins released from interleukin-8-stimulated neutrophils

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12 December 2020

Drosophila innate immunity: an evolutionary perspective

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12 December 2020

PR-39, a syndecan-inducing antimicrobial peptide, binds and affects p130(Cas).

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12 December 2020

Transfer of a cathelicidin peptide antibiotic gene restores bacterial killing in a cystic fibrosis xenograft model

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12 December 2020

Mucoid Pseudomonas aeruginosa, TNF-alpha, and IL-1beta, but not IL-6, induce human beta-defensin-2 in respiratory epithelia

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12 December 2020

Transfer of a gene encoding the anticandidal protein histatin 3 to salivary glands

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12 December 2020

Amphipathic alpha helical antimicrobial peptides

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12 December 2020

hCAP-18, a cathelin/pro-bactenecin-like protein of human neutrophil specific granules

1 reference

12 December 2020

Discovery of new human beta-defensins using a genomics-based approach

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12 December 2020

PR-39, a proline/arginine-rich antimicrobial peptide, exerts cardioprotective effects in myocardial ischemia-reperfusion.

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12 December 2020

Tissue-specific inducible expression of antimicrobial peptide genes in Drosophila surface epithelia.

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12 December 2020

Inhibition of ubiquitin-proteasome pathway-mediated I kappa B alpha degradation by a naturally occurring antibacterial peptide

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12 December 2020

Differences in the concentrations of small, anionic, antimicrobial peptides in bronchoalveolar lavage fluid and in respiratory epithelia of patients with and without cystic fibrosis.

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12 December 2020

Lantibiotics: structure, biosynthesis and mode of action

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12 December 2020

How do bacteria resist human antimicrobial peptides?

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12 December 2020

Statistical analysis of alamethicin channels in black lipid membranes

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12 December 2020

PR39, a peptide regulator of angiogenesis

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12 December 2020

Cutting edge: IFN-inducible ELR- CXC chemokines display defensin-like antimicrobial activity

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12 December 2020

The human gene FALL39 and processing of the cathelin precursor to the antibacterial peptide LL-37 in granulocytes

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12 December 2020

Cutaneous injury induces the release of cathelicidin anti-microbial peptides active against group A Streptococcus

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12 December 2020

Antimicrobial peptides as mediators of epithelial host defense

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12 December 2020

Isolation and structure of corticostatin peptides from rabbit fetal and adult lung

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12 December 2020

Apolipoprotein A-I binds and inhibits the human antibacterial/cytotoxic peptide LL-37

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12 December 2020

Effect of local application of the antimicrobial peptide IB-367 on the incidence and severity of oral mucositis in hamsters

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12 December 2020

Use of the cell wall precursor lipid II by a pore-forming peptide antibiotic.

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12 December 2020

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12 December 2020

Mechanism of interaction of different classes of cationic antimicrobial peptides with planar bilayers and with the cytoplasmic membrane of Escherichia coli

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12 December 2020

Bilayer interactions of indolicidin, a small antimicrobial peptide rich in tryptophan, proline, and basic amino acids

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12 December 2020

Protective effects of a human 18-kilodalton cationic antimicrobial protein (CAP18)-derived peptide against murine endotoxemia

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12 December 2020

Production of beta-defensins by human airway epithelia

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12 December 2020

Hydrophobicity, hydrophobic moment and angle subtended by charged residues modulate antibacterial and haemolytic activity of amphipathic helical peptides.

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12 December 2020

Mediators of innate immunity that target immature, but not mature, dendritic cells induce antitumor immunity when genetically fused with nonimmunogenic tumor antigens

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12 December 2020

T-cell release of granulysin contributes to host defense in leprosy.

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12 December 2020

Antimicrobial peptide defense in Drosophila

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12 December 2020

Antimicrobial peptides: properties and applicability

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12 December 2020

Plasma defensin concentrations are elevated in patients with septicemia or bacterial meningitis

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12 December 2020

Structural features of helical antimicrobial peptides: their potential to modulate activity on model membranes and biological cells

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12 December 2020

Expression and regulation of the human beta-defensins hBD-1 and hBD-2 in intestinal epithelium.

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12 December 2020

NF-kappa B-mediated transcriptional regulation of human beta-defensin-2 gene following lipopolysaccharide stimulation

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12 December 2020

Augmentation of innate host defense by expression of a cathelicidin antimicrobial peptide.

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12 December 2020

Bacteriocins: nature, function and structure

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12 December 2020

Posttranslationally modified bacteriocins--the lantibiotics

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12 December 2020

Rapid membrane permeabilization and inhibition of vital functions of gram-negative bacteria by bactenecins

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12 December 2020

beta-Defensin 1 contributes to pulmonary innate immunity in mice

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12 December 2020

Tracheal antimicrobial peptide, a cysteine-rich peptide from mammalian tracheal mucosa: peptide isolation and cloning of a cDNA.

1 reference

12 December 2020

Drosophila host defense: differential induction of antimicrobial peptide genes after infection by various classes of microorganisms

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12 December 2020

RL-37, an alpha-helical antimicrobial peptide of the rhesus monkey

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12 December 2020

Salt-independent abnormality of antimicrobial activity in cystic fibrosis airway surface fluid

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12 December 2020

Antimicrobial peptides from Mirabilis jalapa and Amaranthus caudatus: expression, processing, localization and biological activity in transgenic tobacco

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12 December 2020

Rhesus monkey (Macaca mulatta) mucosal antimicrobial peptides are close homologues of human molecules

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12 December 2020

Two distinct pathways can control expression of the gene encoding the Drosophila antimicrobial peptide metchnikowin.

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12 December 2020

Liposomal entrapment of the neutrophil-derived peptide indolicidin endows it with in vivo antifungal activity

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12 December 2020

Modular structure of genes encoding multifunctional peptide synthetases required for non-ribosomal peptide synthesis

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12 December 2020

Human neutrophil defensin and serpins form complexes and inactivate each other

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12 December 2020

The dorsoventral regulatory gene cassette spätzle/Toll/cactus controls the potent antifungal response in Drosophila adults

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12 December 2020

Granulysin: a novel antimicrobial peptide of cytolytic T lymphocytes and natural killer cells

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12 December 2020

Transgenic expression of a gene encoding a synthetic antimicrobial peptide results in inhibition of fungal growth in vitro and in planta

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12 December 2020

Antibacterial agents based on the cyclic D,L-alpha-peptide architecture

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12 December 2020

The clinical use of colistin in patients with cystic fibrosis

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12 December 2020

Downregulation of bactericidal peptides in enteric infections: a novel immune escape mechanism with bacterial DNA as a potential regulator

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12 December 2020

Beta-defensins: linking innate and adaptive immunity through dendritic and T cell CCR6

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12 December 2020

The peptide antibiotic LL-37/hCAP-18 is expressed in epithelia of the human lung where it has broad antimicrobial activity at the airway surface

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12 December 2020

Interactions of an antimicrobial peptide, magainin 2, with lipopolysaccharide-containing liposomes as a model for outer membranes of gram-negative bacteria

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12 December 2020

Structure of the bovine antimicrobial peptide indolicidin bound to dodecylphosphocholine and sodium dodecyl sulfate micelles

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12 December 2020

Production of beta-defensin-2 by human colonic epithelial cells induced by Salmonella enteritidis flagella filament structural protein

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12 December 2020

Syndecans, cell surface heparan sulfate proteoglycans, are induced by a proline-rich antimicrobial peptide from wounds

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12 December 2020

Production of active bovine tracheal antimicrobial peptide in milk of transgenic mice

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12 December 2020

Effect of neutrophil serine proteinases and defensins on lung epithelial cells: modulation of cytotoxicity and IL-8 production.

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12 December 2020

Human beta-defensin 2 is a salt-sensitive peptide antibiotic expressed in human lung

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12 December 2020

LL-37, the neutrophil granule- and epithelial cell-derived cathelicidin, utilizes formyl peptide receptor-like 1 (FPRL1) as a receptor to chemoattract human peripheral blood neutrophils, monocytes, and T cells

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12 December 2020

An approach combining rapid cDNA amplification and chemical synthesis for the identification of novel, cathelicidin-derived, antimicrobial peptides

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12 December 2020

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12 December 2020

Constitutive expression of a single antimicrobial peptide can restore wild-type resistance to infection in immunodeficient Drosophila mutants

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12 December 2020

hBD-1: a novel beta-defensin from human plasma

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12 December 2020

Plant defense peptides

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12 December 2020

An antimicrobial peptide gene found in the male reproductive system of rats.

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12 December 2020

A cyclic antimicrobial peptide produced in primate leukocytes by the ligation of two truncated alpha-defensins

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12 December 2020

Defensins: endogenous antibiotic peptides of animal cells

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12 December 2020

Human CAP18: a novel antimicrobial lipopolysaccharide-binding protein

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12 December 2020

An antimicrobial activity of cytolytic T cells mediated by granulysin

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12 December 2020

Enhanced expression of an antimicrobial peptide sarcotoxin IA by GUS fusion in transgenic tobacco plants.

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12 December 2020

Influence of the angle subtended by the positively charged helix face on the membrane activity of amphipathic, antibacterial peptides.

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12 December 2020

Human Toll-like receptor 2 mediates induction of the antimicrobial peptide human beta-defensin 2 in response to bacterial lipoprotein

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12 December 2020

Human beta-defensin 4: a novel inducible peptide with a specific salt-sensitive spectrum of antimicrobial activity

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12 December 2020

Secondary structure and membrane interaction of PR-39, a Pro+Arg-rich antibacterial peptide.

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12 December 2020

Development of short antimicrobial peptides derived from host defense peptides or by combinatorial libraries

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12 December 2020

Mouse beta-defensin 3 is an inducible antimicrobial peptide expressed in the epithelia of multiple organs.

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12 December 2020

Human airway epithelia express a beta-defensin

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12 December 2020

Peptide hydrophobicity controls the activity and selectivity of magainin 2 amide in interaction with membranes.

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12 December 2020

Innate antimicrobial peptide protects the skin from invasive bacterial infection

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12 December 2020

Membrane channel formation by antimicrobial protegrins

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12 December 2020

Mode of action of the antimicrobial peptide indolicidin.

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12 December 2020

Purification and characterization of defensins from cystic fibrosis sputum

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12 December 2020

PR-39, a potent neutrophil inhibitor, attenuates myocardial ischemia-reperfusion injury in mice

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12 December 2020

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12 December 2020

A 450-kb contig of defensin genes on human chromosome 8p23.

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12 December 2020

Human beta-defensin-1 is a salt-sensitive antibiotic in lung that is inactivated in cystic fibrosis

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12 December 2020

Synthesis of novel unnatural amino acid as a building block and its incorporation into an antimicrobial peptide

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12 December 2020

10.2165/00003495-200363040-00005

Identifiers

DOI

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PubMed ID

12558461

Dimensions Publication ID

6 August 2017

0 references

1 reference

PubMed ID

12558461