Generation of heavy-chain-only antibodies in mice (Q35062276)

6 August 2017

title

Generation of heavy-chain-only antibodies in mice (English)

1 reference

6 August 2017

Rick Janssens

1

1 reference

6 August 2017

Sylvia Dekker

2

1 reference

6 August 2017

Rudi W Hendriks

3

1 reference

6 August 2017

George Panayotou

4

1 reference

6 August 2017

Alexandra van Remoortere

5

1 reference

6 August 2017

John Kong-a San

6

1 reference

6 August 2017

Frank Grosveld

7

1 reference

6 August 2017

Dubravka Drabek

8

1 reference

6 August 2017

language of work or name

English

0 references

publication date

2 October 2006

1 reference

Proceedings of the National Academy of Sciences of the United States of America

6 August 2017

published in

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6 August 2017

volume

103

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6 August 2017

issue

41

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6 August 2017

page(s)

15130-15135

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Antibody repertoire development in camelids

6 August 2017

cites work

1 reference

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8 July 2018

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Expressed murine and human CDR-H3 intervals of equal length exhibit distinct repertoires that differ in their amino acid composition and predicted range of structures

8 July 2018

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Intracellularly Expressed Single-Domain Antibody against p15 Matrix Protein Prevents the Production of Porcine Retroviruses

8 July 2018

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Emergence and evolution of functional heavy-chain antibodies in Camelidae

8 July 2018

1 reference

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Functional heavy-chain antibodies in Camelidae

8 July 2018

1 reference

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The VpreB protein of the surrogate light-chain can pair with some mu heavy-chains in the absence of the lambda 5 protein

8 July 2018

1 reference

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Recognition of antigens by single-domain antibody fragments: the superfluous luxury of paired domains

8 July 2018

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Loss of precursor B cell expansion but not allelic exclusion in VpreB1/VpreB2 double-deficient mice

8 July 2018

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Modification of human beta-globin locus PAC clones by homologous recombination in Escherichia coli

8 July 2018

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Exploring the sequence space for tetracycline-dependent transcriptional activators: novel mutations yield expanded range and sensitivity

8 July 2018

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Gene dose-dependent maturation and receptor editing of B cells expressing immunoglobulin (Ig)G1 or IgM/IgG1 tail antigen receptors

8 July 2018

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Camel heavy-chain antibodies: diverse germline V(H)H and specific mechanisms enlarge the antigen-binding repertoire

8 July 2018

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Single domain antibodies: comparison of camel VH and camelised human VH domains

8 July 2018

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8 July 2018

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The structure of the llama heavy chain constant genes reveals a mechanism for heavy-chain antibody formation

8 July 2018

1 reference

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Loss of splice consensus signal is responsible for the removal of the entire C(H)1 domain of the functional camel IGG2A heavy-chain antibodies

8 July 2018

1 reference

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Potent enzyme inhibitors derived from dromedary heavy-chain antibodies

8 July 2018

1 reference

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Enhancer complexes located downstream of both human immunoglobulin Calpha genes

8 July 2018

1 reference

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A truncated heavy chain protein relieves the requirement for surrogate light chains in early B cell development.

8 July 2018

1 reference

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Single antibody domains as small recognition units: design and in vitro antigen selection of camelized, human VH domains with improved protein stability

8 July 2018

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A simple assay to determine the functionality of Cre or FLP recombination targets in genomic manipulation constructs.

8 July 2018

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Pre-B-cell development in the absence of lambda 5 in transgenic mice expressing a heavy-chain disease protein

8 July 2018

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Naturally occurring antibodies devoid of light chains

8 July 2018

1 reference

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Loss of a consensus splice signal in a mutant immunoglobulin gene eliminates the CH1 domain exon from the mRNA

8 July 2018

1 reference

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A B cell-deficient mouse by targeted disruption of the membrane exon of the immunoglobulin mu chain gene

8 July 2018

1 reference

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Molecular requirements for the mu-induced light chain gene rearrangement in pre-B cells

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1586177

Novel B cell population producing functional IgG in the absence of membrane IgM expression.

8 July 2018

1 reference

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Incomplete block of B cell development and immunoglobulin production in mice carrying the muMT mutation on the BALB/c background.

27 September 2018

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Impaired precursor B cell differentiation in Bruton's tyrosine kinase-deficient mice.

27 September 2018

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IgA production without mu or delta chain expression in developing B cells.

27 September 2018

1 reference

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Diversity in the CDR3 region of V(H) is sufficient for most antibody specificities

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1586177

B cell development under the condition of allelic inclusion.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1586177

Antibody expression from the core region of the human IgH locus reconstructed in transgenic mice using bacteriophage P1 clones

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1586177

Heavy-chain only antibodies derived from dromedary are secreted and displayed by mouse B cells

27 September 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0601108103

Strongin VivoMaturation Compensates for Structurally Restricted H3 Loops in Antibody Repertoires

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0601108103

Antigen Binding and Solubility Effects upon the Veneering of a Camel VHH in Framework-2 to Mimic a VH

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0601108103

Comparison of llama VH sequences from conventional and heavy chain antibodies

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0601108103

Expression of individual immunoglobulin genes occurs in an unusual system consisting of multiple independent loci

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0601108103

Widespread recombinase expression using FLPeR (flipper) mice

21 January 2018

1 reference

12 December 2020

Allelic exclusion in transgenic mice expressing a heavy chain disease-like human mu protein

1 reference

12 December 2020

IMGT, the international ImMunoGeneTics database

1 reference

12 December 2020

BiP-binding sequences in HIV gp160. Implications for the binding specificity of bip

1 reference

12 December 2020

Expression of a dromedary heavy chain-only antibody and B cell development in the mouse

1 reference

12 December 2020

Identifiers

DOI

10.1073/PNAS.0601108103

1 reference

6 August 2017

0 references

1 reference

6 August 2017

1 reference