Advancing drug discovery through systems biology (Q35064582)

6 August 2017

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title

Advancing drug discovery through systems biology (English)

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6 August 2017

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EugeneJ Davidov

1

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6 August 2017

JoanneM Holland

series ordinal

2

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6 August 2017

EdwardW Marple

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3

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6 August 2017

Stephen Naylor

series ordinal

4

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6 August 2017

1 February 2003

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6 August 2017

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6 August 2017

8

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6 August 2017

4

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6 August 2017

175-183

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How to escape the bottleneck of medicinal chemistry

6 August 2017

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https://api.crossref.org/works/10.1016%2FS1359-6446%2803%2902600-X

7 January 2021

Chemical space navigation in lead discovery

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2803%2902600-X

7 January 2021

Quantitative monitoring of gene expression patterns with a complementary DNA microarray

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2803%2902600-X

7 January 2021

Protein microarray technology

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2803%2902600-X

7 January 2021

Dissecting glucose signalling with diversity-oriented synthesis and small-molecule microarrays.

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2803%2902600-X

7 January 2021

Functional genomics: it's all how you read it

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2803%2902600-X

7 January 2021

Chemical genomics in the global study of protein functions

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2803%2902600-X

7 January 2021

Drug discovery: a historical perspective

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https://api.crossref.org/works/10.1016%2FS1359-6446%2803%2902600-X

7 January 2021

Target validation of G-protein coupled receptors

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https://api.crossref.org/works/10.1016%2FS1359-6446%2803%2902600-X

7 January 2021

Systems biology--the new R&D buzzword?

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https://api.crossref.org/works/10.1016%2FS1359-6446%2803%2902600-X

7 January 2021

Systems biology: a brief overview

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https://api.crossref.org/works/10.1016%2FS1359-6446%2803%2902600-X

7 January 2021

Reverse engineering of biological complexity

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https://api.crossref.org/works/10.1016%2FS1359-6446%2803%2902600-X

7 January 2021

All creatures great and small

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https://api.crossref.org/works/10.1016%2FS1359-6446%2803%2902600-X

7 January 2021

Feedback control of intercellular signalling in development

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2803%2902600-X

7 January 2021

Network motifs: simple building blocks of complex networks

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2803%2902600-X

7 January 2021

An expanded role for microbial physiology in metabolic engineering and functional genomics: moving towards systems biology

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2803%2902600-X

7 January 2021

Metabolic control analysis in drug discovery and disease

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2803%2902600-X

7 January 2021

Genomics to fluxomics and physiomics — pathway engineering

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2803%2902600-X

7 January 2021

Metabolite profiling for plant functional genomics

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2803%2902600-X

7 January 2021

Metabolic profiling on the right path

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https://api.crossref.org/works/10.1016%2FS1359-6446%2803%2902600-X

7 January 2021

A functional genomics strategy that uses metabolome data to reveal the phenotype of silent mutations

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2803%2902600-X

7 January 2021

'Metabonomics': understanding the metabolic responses of living systems to pathophysiological stimuli via multivariate statistical analysis of biological NMR spectroscopic data

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2803%2902600-X

7 January 2021

Simultaneous analysis of metabolites in potato tuber by gas chromatography-mass spectrometry

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https://api.crossref.org/works/10.1016%2FS1359-6446%2803%2902600-X

7 January 2021

Large-scale prediction of phenotype: concept

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2803%2902600-X

7 January 2021

Minimal reaction sets for Escherichia coli metabolism under different growth requirements and uptake environments

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2803%2902600-X

7 January 2021

Metabolic profiles of dystrophin and utrophin expression in mouse models of Duchenne muscular dystrophy

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2803%2902600-X

7 January 2021

Surrogate endpoints in cancer drug development.

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2803%2902600-X

7 January 2021

Predicting ADME properties in silico: methods and models

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2803%2902600-X

7 January 2021

NMR-based metabolomics

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2803%2902600-X

7 January 2021

The challenges of in silico biology

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https://api.crossref.org/works/10.1016%2FS1359-6446%2803%2902600-X

7 January 2021

Synthetic cell biology

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https://api.crossref.org/works/10.1016%2FS1359-6446%2803%2902600-X

7 January 2021

The dynamics of molecular networks: applications to therapeutic discovery

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2803%2902600-X

7 January 2021

Sildenafil (VIAGRATM), a potent and selective inhibitor of type 5 cGMP phosphodiesterase with utility for the treatment of male erectile dysfunction

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2803%2902600-X

7 January 2021

Glivec (STI571, imatinib), a rationally developed, targeted anticancer drug

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2803%2902600-X

7 January 2021

G-protein-coupled receptors and signaling networks: emerging paradigms.

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2803%2902600-X

7 January 2021

Emerging targets for the treatment of depressive disorder

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2803%2902600-X

7 January 2021

Integrated genomic and proteomic analyses of a systematically perturbed metabolic network

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2803%2902600-X

7 January 2021

A genomic-systems biology map for cardiovascular function

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2803%2902600-X

7 January 2021

Knowledge assembly for the life sciences.

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2803%2902600-X

7 January 2021

10.1016/S1359-6446(03)02600-X

Identifiers

DOI

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6 August 2017

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