An Lmx1b-miR135a2 regulatory circuit modulates Wnt1/Wnt signaling and determines the size of the midbrain dopaminergic progenitor pool (Q35069200)

6 August 2017

title

An Lmx1b-miR135a2 regulatory circuit modulates Wnt1/Wnt signaling and determines the size of the midbrain dopaminergic progenitor pool (English)

1 reference

6 August 2017

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Jun-An Chen

3

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author name string

Angela Anderegg

1

1 reference

6 August 2017

Hsin-Pin Lin

2

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6 August 2017

Giuliana Caronia-Brown

4

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6 August 2017

Natalya Cherepanova

5

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6 August 2017

Beth Yun

6

1 reference

6 August 2017

Milan Joksimovic

7

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6 August 2017

Jason Rock

8

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6 August 2017

Brian D Harfe

9

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6 August 2017

Randy Johnson

10

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6 August 2017

Rajeshwar Awatramani

11

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6 August 2017

publication date

12 December 2013

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6 August 2017

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6 August 2017

volume

9

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6 August 2017

issue

12

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6 August 2017

page(s)

e1003973

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Creative Commons Attribution 3.0 Unported

6 August 2017

copyright license

start time

12 December 2013

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

describes a project that uses

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3861205/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

cites work

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8 July 2018

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8 July 2018

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8 July 2018

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8 July 2018

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8 July 2018

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8 July 2018

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8 July 2018

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8 July 2018

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8 July 2018

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A Wnt1-regulated genetic network controls the identity and fate of midbrain-dopaminergic progenitors in vivo

8 July 2018

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Animal MicroRNAs confer robustness to gene expression and have a significant impact on 3'UTR evolution

8 July 2018

1 reference

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Otx2 regulates subtype specification and neurogenesis in the midbrain

8 July 2018

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Conserved seed pairing, often flanked by adenosines, indicates that thousands of human genes are microRNA targets

8 July 2018

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MicroRNA-responsive 'sensor' transgenes uncover Hox-like and other developmentally regulated patterns of vertebrate microRNA expression

8 July 2018

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Evidence for an expansion-based temporal Shh gradient in specifying vertebrate digit identities

8 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3861205

Dynamic changes in the response of cells to positive hedgehog signaling during mouse limb patterning

8 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3861205

Effects of Wnt1 signaling on proliferation in the developing mid-/hindbrain region

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3861205

Differential regulation of midbrain dopaminergic neuron development by Wnt-1, Wnt-3a, and Wnt-5a

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3861205

Directed differentiation of embryonic stem cells into motor neurons

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3861205

Wnt/beta-catenin/Tcf signaling induces the transcription of Axin2, a negative regulator of the signaling pathway

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3861205

Two lineage boundaries coordinate vertebrate apical ectodermal ridge formation.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3861205

A second independent pathway for development of mesencephalic dopaminergic neurons requires Lmx1b.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3861205

Disruption of the glucocorticoid receptor gene in the nervous system results in reduced anxiety

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3861205

Sonic hedgehog, a member of a family of putative signaling molecules, is implicated in the regulation of CNS polarity

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3861205

Expression patterns of the homeo box-containing genes En-1 and En-2 and the proto-oncogene int-1 diverge during mouse development.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3861205

The Wnt-1 (int-1) proto-oncogene is required for development of a large region of the mouse brain

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3861205

A role for midbrain arcs in nucleogenesis

8 July 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PGEN.1003973

Helt determines GABAergic over glutamatergic neuronal fate by repressing Ngn genes in the developing mesencephalon

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PGEN.1003973

Identification of intrinsic determinants of midbrain dopamine neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PGEN.1003973

Identification of genes expressed in the mouse limb using a novel ZPA microarray approach.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PGEN.1003973

Lmx1a and lmx1b function cooperatively to regulate proliferation, specification, and differentiation of midbrain dopaminergic progenitors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PGEN.1003973

The isthmic organizer signal FGF8 is required for cell survival in the prospective midbrain and cerebellum.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PGEN.1003973

Anterior-posterior graded response to Otx2 controls proliferation and differentiation of dopaminergic progenitors in the ventral mesencephalon

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PGEN.1003973

Brain area-specific effect of TGF-beta signaling on Wnt-dependent neural stem cell expansion.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PGEN.1003973

Generation of regionally specified neural progenitors and functional neurons from human embryonic stem cells under defined conditions

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PGEN.1003973

Role of Lmx1b and Wnt1 in mesencephalon and metencephalon development.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3861205

The transcription factor Lmx1b maintains Wnt1 expression within the isthmic organizer.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3861205

FGF8 can activate Gbx2 and transform regions of the rostral mouse brain into a hindbrain fate.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3861205

MicroRNA control of Nodal signalling

27 September 2018

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https://api.crossref.org/works/10.1371%2FJOURNAL.PGEN.1003973

SnapShot: Wnt/beta-catenin signaling

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24348261

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1371/JOURNAL.PGEN.1003973

1 reference

6 August 2017

1 reference

6 August 2017

1 reference