The immune-modulating cytokine and endogenous Alarmin interleukin-33 is upregulated in skin exposed to inflammatory UVB radiation (Q35070173)

6 August 2017

The immune-modulating cytokine and endogenous Alarmin interleukin-33 is upregulated in skin exposed to inflammatory UVB radiation (English)

1 reference

6 August 2017

Scott Napier Byrne

1

1 reference

6 August 2017

Clare Beaugie

2

1 reference

6 August 2017

Clare O'Sullivan

3

1 reference

6 August 2017

Sarah Leighton

4

1 reference

6 August 2017

Gary M Halliday

5

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6 August 2017

language of work or name

English

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publication date

13 May 2011

1 reference

The American Journal of Pathology

6 August 2017

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6 August 2017

179

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6 August 2017

1

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6 August 2017

211-222

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describes a project that uses

6 August 2017

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3123869/fullTextXML

inferred from PubMed Central ID database lookup

cites work

IL-33 mediates inflammatory responses in human lung tissue cells

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IL-33 is produced by mast cells and regulates IgE-dependent inflammation

8 July 2018

1 reference

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8-methoxypsoralen plus ultraviolet A therapy acts via inhibition of the IL-23/Th17 axis and induction of Foxp3+ regulatory T cells involving CTLA4 signaling in a psoriasis-like skin disorder

8 July 2018

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Nuocytes represent a new innate effector leukocyte that mediates type-2 immunity

8 July 2018

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Evidence that vitamin D(3) promotes mast cell-dependent reduction of chronic UVB-induced skin pathology in mice

8 July 2018

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Murine epidermal Langerhans cells and keratinocytes express functional P2X7 receptors

8 July 2018

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Caspase 3 inactivates biologically active full length interleukin-33 as a classical cytokine but does not prohibit nuclear translocation

8 July 2018

1 reference

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UVB-induced ERK/AKT-dependent PTEN suppression promotes survival of epidermal keratinocytes

8 July 2018

1 reference

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IL-33 amplifies the polarization of alternatively activated macrophages that contribute to airway inflammation

8 July 2018

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The cytokine interleukin-33 mediates anaphylactic shock

8 July 2018

1 reference

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The IL-1-like cytokine IL-33 is inactivated after maturation by caspase-1

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3123869

IL-33-activated dendritic cells induce an atypical TH2-type response

8 July 2018

1 reference

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Ultraviolet A within sunlight induces mutations in the epidermal basal layer of engineered human skin

8 July 2018

1 reference

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Requirement for metalloproteinase-dependent ERK and AKT activation in UVB-induced G1-S cell cycle progression of human keratinocytes

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3123869

The IL-1-like cytokine IL-33 is constitutively expressed in the nucleus of endothelial cells and epithelial cells in vivo: a novel 'alarmin'?

8 July 2018

1 reference

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Interleukin-33 enhances adhesion, CD11b expression and survival in human eosinophils

8 July 2018

1 reference

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IL-33 exacerbates antigen-induced arthritis by activating mast cells

8 July 2018

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A novel IL-1 family cytokine, IL-33, potently activates human eosinophils

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3123869

ATP is released by monocytes stimulated with pathogen-sensing receptor ligands and induces IL-1beta and IL-18 secretion in an autocrine way

8 July 2018

1 reference

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Inhibition of photocarcinogenesis by platelet-activating factor or serotonin receptor antagonists

8 July 2018

1 reference

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Mast cell migration from the skin to the draining lymph nodes upon ultraviolet irradiation represents a key step in the induction of immune suppression

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3123869

Ultraviolet B suppresses immunity by inhibiting effector and memory T cells

8 July 2018

1 reference

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IL-33 reduces the development of atherosclerosis

8 July 2018

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Mast cell-derived interleukin 10 limits skin pathology in contact dermatitis and chronic irradiation with ultraviolet B.

8 July 2018

1 reference

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IL-33, the IL-1-like cytokine ligand for ST2 receptor, is a chromatin-associated nuclear factor in vivo

8 July 2018

1 reference

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A role for inflammatory mediators in the induction of immunoregulatory B cells

8 July 2018

1 reference

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IL-33, an interleukin-1-like cytokine that signals via the IL-1 receptor-related protein ST2 and induces T helper type 2-associated cytokines

8 July 2018

1 reference

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Prevention of UV radiation-induced immunosuppression by IL-12 is dependent on DNA repair

8 July 2018

1 reference

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The basal layer in human squamous tumors harbors more UVA than UVB fingerprint mutations: a role for UVA in human skin carcinogenesis

8 July 2018

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Molecular characterization of NF-HEV, a nuclear factor preferentially expressed in human high endothelial venules

8 July 2018

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Platelet-activating factor, a molecular sensor for cellular damage, activates systemic immune suppression

8 July 2018

1 reference

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Altered cytokine production in mice lacking P2X(7) receptors

8 July 2018

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Primer3 on the WWW for general users and for biologist programmers

8 July 2018

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The central role of CD4(+) T cells in the antitumor immune response

8 July 2018

1 reference

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Expression of the platelet-activating factor receptor results in enhanced ultraviolet B radiation-induced apoptosis in a human epidermal cell line

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3123869

The effect of UVB irradiation on antibody responses during herpes simplex virus type 1 (HSV-1) infections of mice

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3123869

A cytokine cascade including prostaglandin E2, IL-4, and IL-10 is responsible for UV-induced systemic immune suppression.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3123869

Does immunosuppressive ultraviolet radiation explain the latitude gradient for multiple sclerosis?

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3123869

Platelet-activating factor exerts mitogenic activity and stimulates expression of interleukin 6 and interleukin 8 in human lung fibroblasts via binding to its functional receptor

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3123869

Mechanisms in the suppression of tumor rejection produced in mice by repeated UV irradiation

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3123869

Mechanism of systemic immune suppression by UV irradiation in vivo. II. The UV effects on number and morphology of epidermal Langerhans cells and the UV-induced suppression of contact hypersensitivity have different wavelength dependencies

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3123869

Mechanism of immune suppression by ultraviolet irradiation in vivo. I. Evidence for the existence of a unique photoreceptor in skin and its role in photoimmunology

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3123869

Suppression of the immune response to allogeneic histocompatibility antigens by a single exposure to ultraviolet radiation.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3123869

Isolation and identification of platelet-activating factor in UV-irradiated guinea pig skin

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3123869

Interferon-independent increases in class I major histocompatibility complex antigen expression follow flavivirus infection

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3123869

A putative protein of a growth specific cDNA from BALB/c-3T3 cells is highly similar to the extracellular portion of mouse interleukin 1 receptor

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3123869

Immunosuppression by factors released from UV-irradiated epidermal cells: selective effects on the generation of contact and delayed hypersensitivity after exposure to UVA or UVB radiation

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3123869

Nicotinamide prevents ultraviolet radiation-induced cellular energy loss

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3123869

Interleukin-33 attenuates sepsis by enhancing neutrophil influx to the site of infection

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3123869

IL-33 receptor (T1/ST2) signalling is necessary to prevent the development of encephalitis in mice infected with Toxoplasma gondii.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3123869

UV-B radiation induces the expression of antimicrobial peptides in human keratinocytes in vitro and in vivo.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3123869

The pro-Th2 cytokine IL-33 directly interacts with invariant NKT and NK cells to induce IFN-gamma production.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3123869

An IL-1 cytokine member, IL-33, induces human basophil activation via its ST2 receptor

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3123869

Experimental extracorporeal photopheresis inhibits the sensitization and effector phases of contact hypersensitivity via two mechanisms: generation of IL-10 and induction of regulatory T cells

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3123869

IL-33 induces antigen-specific IL-5+ T cells and promotes allergic-induced airway inflammation independent of IL-4.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3123869

Human epidermal and monocyte-derived langerhans cells express functional P2X receptors

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3123869

Ultraviolet a irradiation of C57BL/6 mice suppresses systemic contact hypersensitivity or enhances secondary immunity depending on dose.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3123869

Suppression of the asthmatic phenotype by ultraviolet B-induced, antigen-specific regulatory cells

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3123869

IL-33 can promote survival, adhesion and cytokine production in human mast cells

16 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3123869

Influence of narrow-band UVB phototherapy on cutaneous microbiota of children with atopic dermatitis

16 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3123869

Differential modulation of human epidermal Langerhans cell maturation by ultraviolet B radiation

16 November 2018

1 reference

12 December 2020

Ultraviolet B-induced suppression of immune responses in interleukin-4-/- mice: relationship to dermal mast cells

1 reference

12 December 2020

Progressor but not regressor skin tumours inhibit Langerhans' cell migration from epidermis to local lymph nodes

1 reference

12 December 2020

Exposure to ultraviolet radiation causes dendritic cells/macrophages to secrete immune-suppressive IL-12p40 homodimers

1 reference

12 December 2020

Ultraviolet B radiation induces a transient appearance of IL-4+ neutrophils, which support the development of Th2 responses

1 reference

12 December 2020

Administration of IL-33 induces airway hyperresponsiveness and goblet cell hyperplasia in the lungs in the absence of adaptive immune system

1 reference

12 December 2020

Neutrophils, differentiated macrophages, and monocyte/macrophage antigen presenting cells infiltrate murine epidermis after UV injury

1 reference

12 December 2020

The role of IL-4, IL-10, and TNF-alpha in the immune suppression induced by ultraviolet radiation

1 reference

12 December 2020

Mast cell modulation of neutrophil influx and bacterial clearance at sites of infection through TNF-α

1 reference

12 December 2020

New insights into the mechanisms of polymorphic light eruption: resistance to ultraviolet radiation-induced immune suppression as an aetiological factor

1 reference

12 December 2020

The alternative complement pathway seems to be a UVA sensor that leads to systemic immunosuppression

1 reference

12 December 2020

Interleukin-33 prevents apoptosis and improves survival after experimental myocardial infarction through ST2 signaling

1 reference

12 December 2020

Phagocytosis by dendritic cells rather than MHC IIhigh macrophages is associated with skin tumour regression

1 reference

12 December 2020

Immunologic parameters of ultraviolet carcinogenesis

1 reference

12 December 2020

Transmission of human epidermis and stratum corneum as a function of thickness in the ultraviolet and visible wavelengths

1 reference

12 December 2020

TNF-α and IL-8 Are Upregulated in the Epidermis of Normal Human Skin after UVB Exposure: Correlation with Neutrophil Accumulation and E-Selectin Expression

1 reference

12 December 2020

Low-dose UVA and UVB have different time courses for suppression of contact hypersensitivity to a recall antigen in humans

1 reference

12 December 2020

B cells activated in lymph nodes in response to ultraviolet irradiation or by interleukin-10 inhibit dendritic cell induction of immunity

1 reference

12 December 2020

Ultraviolet B irradiation selectively increases the production of interleukin-8 in human cord blood-derived mast cells

1 reference

12 December 2020

IL-10 controls ultraviolet-induced carcinogenesis in mice

1 reference

12 December 2020

Cutting edge: The ST2 ligand IL-33 potently activates and drives maturation of human mast cells

1 reference

12 December 2020

Use of Ly6G-specific monoclonal antibody to deplete neutrophils in mice

1 reference

12 December 2020

The IL1-like cytokine IL33 and its receptor ST2 are abnormally expressed in the affected skin and visceral organs of patients with systemic sclerosis

1 reference

12 December 2020

Expression of interleukin 1-like cytokine interleukin 33 and its receptor complex (ST2L and IL1RAcP) in human pancreatic myofibroblasts

1 reference

12 December 2020

A UVB wavelength dependency for local suppression of recall immunity in humans demonstrates a peak at 300 nm

1 reference

12 December 2020

10.1016/J.AJPATH.2011.03.010

Identifiers

DOI

1 reference

6 August 2017

1 reference

6 August 2017

1 reference