Jadomycin breast cancer cytotoxicity is mediated by a copper-dependent, reactive oxygen species-inducing mechanism (Q35073744)

6 August 2017

Jadomycin breast cancer cytotoxicity is mediated by a copper-dependent, reactive oxygen species-inducing mechanism (English)

1 reference

6 August 2017

reactive oxygen species

1 reference

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25729577%20AND%20SRC:MED&resulttype=core&format=json

4 June 2020

author name string

Steven R Hall

1

1 reference

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4 June 2020

Heather L Blundon

2

1 reference

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4 June 2020

Matthew A Ladda

3

1 reference

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4 June 2020

Andrew W Robertson

4

1 reference

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4 June 2020

Camilo F Martinez-Farina

5

1 reference

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4 June 2020

David L Jakeman

6

1 reference

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4 June 2020

publication date

1 March 2015

1 reference

Pharmacology Research & Perspectives

6 August 2017

1 reference

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4 June 2020

volume

3

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4 June 2020

issue

2

1 reference

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4 June 2020

page(s)

e00110

1 reference

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Treatment innovations for metastatic breast cancer: nanoparticle albumin-bound (NAB) technology targeted to tumors.

4 June 2020

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Enhancement of auranofin-induced apoptosis in MCF-7 human breast cells by selenocystine, a synergistic inhibitor of thioredoxin reductase

8 July 2018

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8 July 2018

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The anticancer drug Dp44mT inhibits T-cell activation and CD25 through a copper-dependent mechanism

8 July 2018

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Induction of apoptosis in human ovarian cancer cells by new anticancer compounds, epothilone A and B.

8 July 2018

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8 July 2018

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Jadomycins derived from the assimilation and incorporation of norvaline and norleucine

8 July 2018

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Antioxidant inhibitors potentiate the cytotoxicity of photodynamic therapy

8 July 2018

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Aurora kinase inhibitors as anticancer molecules

8 July 2018

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The Expression Patterns of ER, PR, HER2, CK5/6, EGFR, Ki-67 and AR by Immunohistochemical Analysis in Breast Cancer Cell Lines

8 July 2018

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Functional mimics of glutathione peroxidase: bioinspired synthetic antioxidants.

8 July 2018

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Methods for detection and measurement of hydrogen peroxide inside and outside of cells

8 July 2018

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Implications of anthracycline-resistant and taxane-resistant metastatic breast cancer and new therapeutic options

8 July 2018

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Partial attenuation of cytotoxicity and apoptosis by SOD1 in ischemic renal epithelial cells

8 July 2018

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Redox-directed cancer therapeutics: molecular mechanisms and opportunities

8 July 2018

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Development of a bio-assay for estrogens using estrogen receptor alpha gene expression by MCF7 cells as biomarker

8 July 2018

1 reference

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Antimicrobial activities of jadomycin B and structurally related analogues

8 July 2018

1 reference

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Cancer cell killing via ROS: to increase or decrease, that is the question

8 July 2018

1 reference

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Jadomycin B, an Aurora-B kinase inhibitor discovered through virtual screening

8 July 2018

1 reference

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Stereochemical integrity of oxazolone ring-containing jadomycins.

8 July 2018

1 reference

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An investigation into copper catalyzed D-penicillamine oxidation and subsequent hydrogen peroxide generation

8 July 2018

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The thioredoxin system in cancer

8 July 2018

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Role of thioredoxin in cell growth through interactions with signaling molecules

8 July 2018

1 reference

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Reactive oxygen species in cancer cells: live by the sword, die by the sword.

8 July 2018

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Characterization of gene rearrangements leading to activation of MDR-1.

8 July 2018

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Disruption of the interaction of alpha-synuclein with microtubules enhances cell surface recruitment of the dopamine transporter

8 July 2018

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Role of glutathione peroxidase 1 in breast cancer: loss of heterozygosity and allelic differences in the response to selenium

8 July 2018

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Analysis of Relative Gene Expression Data Using Real-Time Quantitative PCR and the 2−ΔΔCT Method

8 July 2018

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Effects of sodium diethyldithiocarbamate on type II pulmonary epithelial cells in vitro

8 July 2018

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A threshold concept for cancer therapy

8 July 2018

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8 July 2018

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Jadomycins are cytotoxic to ABCB1-, ABCC1-, and ABCG2-overexpressing MCF7 breast cancer cells.

8 July 2018

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Copper-mediated nuclease activity of jadomycin B.

27 September 2018

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N-acetylcysteine for antioxidant therapy: pharmacology and clinical utility

27 September 2018

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27 September 2018

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Culture conditions improving the production of jadomycin B.

27 September 2018

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Novel and expanded jadomycins incorporating non-proteogenic amino acids

27 September 2018

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Novel jadomycins: incorporation of non-natural and natural amino acids

27 September 2018

1 reference

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Coordinated action of glutathione S-transferases (GSTs) and multidrug resistance protein 1 (MRP1) in antineoplastic drug detoxification. Mechanism of GST A1-1- and MRP1-associated resistance to chlorambucil in MCF7 breast carcinoma cells.

27 September 2018

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Synthetic diversification of natural products: semi-synthesis and evaluation of triazole jadomycins

27 September 2018

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Crossref

https://api.crossref.org/works/10.1002%2FPRP2.110

Therapeutic options for metastatic breast cancer

21 January 2018

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Glutathione and glutathione-dependent enzymes in cancer drug resistance

27 September 2018

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12 December 2020

The inhibition of human glutathione S-transferases activity by plant polyphenolic compounds ellagic acid and curcumin

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12 December 2020

Doxorubicin-induced apoptosis in endothelial cells and cardiomyocytes is ameliorated by nitrone spin traps and ebselen. Role of reactive oxygen and nitrogen species

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12 December 2020

Diverse DNA-cleaving capacities of the jadomycins through precursor-directed biosynthesis

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12 December 2020

Improved protocol for colorimetric detection of complement-mediated cytotoxicity based on the measurement of cytoplasmic lactate dehydrogenase activity

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12 December 2020

Identifiers

DOI

10.1002/PRP2.110

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25729577%20AND%20SRC:MED&resulttype=core&format=json

4 June 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25729577%20AND%20SRC:MED&resulttype=core&format=json

4 June 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25729577%20AND%20SRC:MED&resulttype=core&format=json