Prospective pharmacologic therapies for the overactive bladder (Q35076367)

6 August 2017

1 reference

title

Prospective pharmacologic therapies for the overactive bladder (English)

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6 August 2017

1

Karl-Erik Andersson

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6 August 2017

language of work or name

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1 June 2009

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Therapeutic advances in urology

6 August 2017

published in

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6 August 2017

volume

1

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6 August 2017

issue

2

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6 August 2017

page(s)

71-83

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Gabapentin: a Ca2+ channel alpha 2-delta ligand far beyond epilepsy therapy

6 August 2017

cites work

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8 July 2018

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Emerging pharmacological targets in overactive bladder therapy: experimental and clinical evidences

8 July 2018

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Bladder control, urgency, and urge incontinence: evidence from functional brain imaging

8 July 2018

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The effects of dutasteride, tamsulosin and combination therapy on lower urinary tract symptoms in men with benign prostatic hyperplasia and prostatic enlargement: 2-year results from the CombAT study

8 July 2018

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Signal transduction underlying the control of urinary bladder smooth muscle tone by muscarinic receptors and beta-adrenoceptors

8 July 2018

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Tramadol extended-release formulations in the management of pain due to osteoarthritis

8 July 2018

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Therapeutic receptor targets for lower urinary tract dysfunction

8 July 2018

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Deletion of the transient receptor potential cation channel TRPV4 impairs murine bladder voiding

8 July 2018

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Rho-kinase and effects of Rho-kinase inhibition on the lower urinary tract

8 July 2018

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LUTS treatment: future treatment options

8 July 2018

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Imaging bladder sensations

8 July 2018

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GW427353 (solabegron), a novel, selective beta3-adrenergic receptor agonist, evokes bladder relaxation and increases micturition reflex threshold in the dog.

8 July 2018

1 reference

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Overactive bladder treatments in early phase clinical trials

8 July 2018

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A review of combination therapy in patients with benign prostatic hyperplasia

8 July 2018

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Duloxetine compared with placebo for treating women with symptoms of overactive bladder

8 July 2018

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Sildenafil citrate improves erectile function and urinary symptoms in men with erectile dysfunction and lower urinary tract symptoms associated with benign prostatic hyperplasia: a randomized, double-blind trial

8 July 2018

1 reference

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Effect of (R)-2-(2-aminothiazol-4-yl)-4'-{2-[(2-hydroxy-2-phenylethyl)amino]ethyl} acetanilide (YM178), a novel selective beta3-adrenoceptor agonist, on bladder function

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3126054

Mechanisms of disease: involvement of the urothelium in bladder dysfunction

8 July 2018

1 reference

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Tolterodine and tamsulosin for treatment of men with lower urinary tract symptoms and overactive bladder: a randomized controlled trial

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3126054

Anticholinergic drugs in patients with bladder outlet obstruction and lower urinary tract symptoms: A systematic review

8 July 2018

1 reference

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Rho kinase: a target for treating urinary bladder dysfunction?

8 July 2018

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Safety and efficacy of tramadol in the treatment of idiopathic detrusor overactivity: a double-blind, placebo-controlled, randomized study.

8 July 2018

1 reference

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Alpha1-, alpha2- and beta-adrenoceptors in the urinary bladder, urethra and prostate

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3126054

8 July 2018

Micturition and the soul

1 reference

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Combined use of alpha-adrenergic and muscarinic antagonists for the treatment of voiding dysfunction

8 July 2018

1 reference

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Life after PDE4: overcoming adverse events with dual-specificity phosphodiesterase inhibitors

8 July 2018

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Aprepitant: a novel antiemetic for chemotherapy-induced nausea and vomiting

8 July 2018

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Clinical pharmacology of tramadol

8 July 2018

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Urinary bladder contraction and relaxation: physiology and pathophysiology

8 July 2018

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Storage and voiding symptoms: pathophysiologic aspects

8 July 2018

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CNS involvement in overactive bladder: pathophysiology and opportunities for pharmacological intervention

8 July 2018

1 reference

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Cellular and molecular action of the putative GABA-mimetic, gabapentin

8 July 2018

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Mapping of neurokinin-like immunoreactivity in the human brainstem

8 July 2018

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Des (1-3) IGF-I-stimulated growth of human stromal BPH cells is inhibited by a vitamin D3 analogue

8 July 2018

1 reference

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Sildenafil influences lower urinary tract symptoms.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3126054

Bladder activation: afferent mechanisms

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3126054

Phosphodiesterase 1 inhibition in the treatment of lower urinary tract dysfunction: from bench to bedside

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3126054

Tachykinins as modulators of the micturition reflex in the central and peripheral nervous system

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3126054

K(ATP) channels mediate the beta(2)-adrenoceptor agonist-induced relaxation of rat detrusor muscle.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3126054

Role of supraspinal tachykinins for volume- and L-dopa-induced bladder activity in normal conscious rats

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3126054

Functional and molecular biological evidence for a possible beta3-adrenoceptor in the human detrusor muscle

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3126054

The role of cyclic nucleotides in guinea-pig bladder contractility

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3126054

The novel anticonvulsant drug, gabapentin (Neurontin), binds to the alpha2delta subunit of a calcium channel

8 July 2018

1 reference

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Pharmacology of lower urinary tract smooth muscles and penile erectile tissues.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3126054

Role of intrathecal tachykinins for micturition in unanaesthetized rats with and without bladder outlet obstruction

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3126054

Effects of Neurokinin Receptor Antagonists on L-DOPA Induced Bladder Hyperactivity in Normal Conscious Rats

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3126054

Effect of tolterodine extended release with or without tamsulosin on measures of urgency and patient reported outcomes in men with lower urinary tract symptoms.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3126054

How many drugs for LUTS due to BPH are too many?

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3126054

Effects of the beta 3-adrenergic receptor agonist disodium 5-[(2R)-2-[[(2R)-2-(3-chlorophenyl)-2-hydroxyethyl]amino]propyl]-1,3-benzodioxole-2,2-dicarboxylate (CL-316243) on bladder micturition reflex in spontaneously hypertensive rats

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3126054

Expression and functional role of beta-adrenoceptors in the human urinary bladder urothelium

27 September 2018

1 reference

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A randomised, placebo-controlled study to assess the efficacy of twice-daily vardenafil in the treatment of lower urinary tract symptoms secondary to benign prostatic hyperplasia

27 September 2018

1 reference

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The effects of a type 4 phosphodiesterase inhibitor and the muscarinic cholinergic antagonist tolterodine tartrate on detrusor overactivity in female rats with bladder outlet obstruction

27 September 2018

1 reference

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Distribution and function of the hydrogen sulfide-sensitive TRPA1 ion channel in rat urinary bladder

27 September 2018

1 reference

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Transient receptor potential channel A1 involved in sensory transduction of rat urinary bladder through C-fiber pathway

27 September 2018

1 reference

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Effects of IP-751, ajulemic acid, on bladder overactivity induced by bladder irritation in rats

27 September 2018

1 reference

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Activation of urothelial transient receptor potential vanilloid 4 by 4alpha-phorbol 12,13-didecanoate contributes to altered bladder reflexes in the rat.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3126054

Effect of lumbar-epidural administration of tramadol on lower urinary tract function

27 September 2018

1 reference

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BXL-628, a vitamin D receptor agonist effective in benign prostatic hyperplasia treatment, prevents RhoA activation and inhibits RhoA/Rho kinase signaling in rat and human bladder.

27 September 2018

1 reference

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Suppression of detrusor overactivity in rats with bladder outlet obstruction by a type 4 phosphodiesterase inhibitor.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3126054

Efficacy and safety of a neurokinin-1 receptor antagonist in postmenopausal women with overactive bladder with urge urinary incontinence

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3126054

Population-based survey of urinary incontinence, overactive bladder, and other lower urinary tract symptoms in five countries: results of the EPIC study.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3126054

Effects of a vitamin D(3) analogue in a rat model of bladder outlet obstruction.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3126054

Combination treatment with propiverine hydrochloride plus doxazosin controlled release gastrointestinal therapeutic system formulation for overactive bladder and coexisting benign prostatic obstruction: a prospective, randomized, controlled multicen

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3126054

Involvement of cyclic AMP-dependent and -independent mechanisms in the relaxation of rat detrusor muscle via beta-adrenoceptors

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3126054

Elimination of rat spinal neurons expressing neurokinin 1 receptors reduces bladder overactivity and spinal c-fos expression induced by bladder irritation

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3126054

Gabapentin for overactive bladder and nocturia after anticholinergic failure

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3126054

Does cyclic AMP mediate rat urinary bladder relaxation by isoproterenol?

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3126054

Human bladder as a novel target for vitamin D receptor ligands

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3126054

Comparison of doxazosin with or without tolterodine in men with symptomatic bladder outlet obstruction and an overactive bladder

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3126054

Phosphodiesterase-linked inhibition of nonmicturition activity in the isolated bladder

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3126054

Inhibition of prostate cell growth by BXL-628, a calcitriol analogue selected for a phase II clinical trial in patients with benign prostate hyperplasia.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3126054

The long-term effect of doxazosin, finasteride, and combination therapy on the clinical progression of benign prostatic hyperplasia

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3126054

Effects of Tramadol on Rat Detrusor Overactivity Induced by Experimental Cerebral Infarction

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3126054

A quantitative analysis of mRNA expression of alpha 1 and beta-adrenoceptor subtypes and their functional roles in human normal and obstructed bladders

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3126054

Inhibition of spontaneous and androgen-induced prostate growth by a nonhypercalcemic calcitriol analog

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3126054

Tramadol inhibits rat detrusor overactivity caused by dopamine receptor stimulation

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3126054

Combination treatment with an alpha-blocker plus an anticholinergic for bladder outlet obstruction: a prospective, randomized, controlled study

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3126054

Overactive bladder symptoms: do we need urodynamics?

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3126054

Autoradiographic distribution of tachykinin NK2 binding sites in the rat brain: comparison with NK1 and NK3 binding sites

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3126054

Effects of beta(3)-adrenoceptor stimulation on prostaglandin E(2)-induced bladder hyperactivity and on the cardiovascular system in conscious rats

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3126054

Effects of selective beta2 and beta3-adrenoceptor agonists on detrusor hyperreflexia in conscious cerebral infarcted rats

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3126054

Characterization and functional relevance of cyclic nucleotide phosphodiesterase isoenzymes of the human prostate

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3126054

Efficacy of the beta3-adrenergic receptor agonist CL-316243 on experimental bladder hyperreflexia and detrusor instability in the rat.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3126054

Relaxant effects of isoproterenol and selective beta3-adrenoceptor agonists on normal, low compliant and hyperreflexic human bladders

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3126054

Role of supraspinal tachykinins for micturition in conscious rats with and without bladder outlet obstruction

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3126054

GRC 6211, A NEW ORAL TRPV1 ANTAGONIST, DECREASES THE FREQUENCY OF BLADDER REFLEX CONTRACTIONS AND NOXIOUS INPUT IN RATS WITH ACUTE OR CHRONIC CYSTITIS

27 September 2018

1 reference

Crossref

https://api.crossref.org/works/10.1177%2F1756287209103937

Detrusor instability in men: correlation of lower urinary tract symptoms with urodynamic findings

21 January 2018

1 reference

12 December 2020

Relaxation of human detrusor muscle by selective beta-2 and beta-3 agonists and endogenous catecholamines

1 reference

12 December 2020

The effects of a new selective beta3-adrenoceptor agonist (GW427353) on spontaneous activity and detrusor relaxation in human bladder

1 reference

12 December 2020

Influence of temperature on urethra to bladder micturition reflex in the awake ewe

1 reference

12 December 2020

Gabapentin Treatment of Neurogenic Overactive Bladder

1 reference

12 December 2020

Emerging drugs for treatment of overactive bladder and detrusor overactivity

1 reference

12 December 2020

Tadalafil relieves lower urinary tract symptoms secondary to benign prostatic hyperplasia

1 reference

12 December 2020

Evidence for beta3-adrenoceptor subtypes in relaxation of the human urinary bladder detrusor: analysis by molecular biological and pharmacological methods

1 reference

12 December 2020

Expression and possible functional role of the beta3-adrenoceptor in human and rat detrusor muscle

1 reference

12 December 2020

Initial clinical experience with the selective phosphodiesterase-I isoenzyme inhibitor vinpocetine in the treatment of urge incontinence and low compliance bladder

1 reference

12 December 2020

Function and distribution of beta3-adrenoceptors in rat, rabbit and human urinary bladder and external urethral sphincter

1 reference

12 December 2020

Identifiers

DOI

10.1177/1756287209103937

1 reference

6 August 2017

1 reference

6 August 2017

1 reference