Prevention of stroke and dementia with statins: Effects beyond lipid lowering (Q35077221)

6 August 2017

1 reference

title

Prevention of stroke and dementia with statins: Effects beyond lipid lowering (English)

1 reference

6 August 2017

1 reference

1 reference

Carl J Vaughan

1

1 reference

6 August 2017

language of work or name

English

0 references

publication date

1 February 2003

1 reference

American Journal of Cardiology

6 August 2017

published in

1 reference

6 August 2017

volume

91

1 reference

6 August 2017

issue

4A

1 reference

6 August 2017

page(s)

23B-29B

1 reference

American Heart Association Prevention Conference. IV. Prevention and Rehabilitation of Stroke. Risk factors

6 August 2017

cites work

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9149%2802%2903270-8

Current status of risk factors for stroke

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9149%2802%2903270-8

Effects of statins on carotid disease and stroke

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9149%2802%2903270-8

Cholesterol reduction and the risk for stroke in men. A meta-analysis of randomized, controlled trials

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9149%2802%2903270-8

American Heart Association Prevention Conference IV: Prevention and Rehabilitation of Stroke

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9149%2802%2903270-8

Cholesterol reduction: weighing the benefits and risks

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9149%2802%2903270-8

Serum cholesterol levels and six-year mortality from stroke in 350,977 men screened for the multiple risk factor intervention trial

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9149%2802%2903270-8

Cholesterol, diastolic blood pressure, and stroke: 13 000 strokes in 450 000 people in 45 prospective cohorts

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9149%2802%2903270-8

The effect of pravastatin on coronary events after myocardial infarction in patients with average cholesterol levels. Cholesterol and Recurrent Events Trial investigators

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9149%2802%2903270-8

Pravastatin Therapy and the Risk of Stroke

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9149%2802%2903270-8

Stroke, statins, and cholesterol. A meta-analysis of randomized, placebo-controlled, double-blind trials with HMG-CoA reductase inhibitors

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9149%2802%2903270-8

Reductase inhibitor monotherapy and stroke prevention

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9149%2802%2903270-8

Effects of atorvastatin on early recurrent ischemic events in acute coronary syndromes: the MIRACL study: a randomized controlled trial

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9149%2802%2903270-8

Effects of atorvastatin on stroke in patients with unstable angina or non-Q-wave myocardial infarction: a Myocardial Ischemia Reduction with Aggressive Cholesterol Lowering (MIRACL) substudy

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9149%2802%2903270-8

MRC/BHF Heart Protection Study of cholesterol lowering with simvastatin in 20,536 high-risk individuals: a randomised placebo-controlled trial

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9149%2802%2903270-8

Regulation of the mevalonate pathway

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9149%2802%2903270-8

Drug treatment of lipid disorders

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9149%2802%2903270-8

The cellular functions of small GTP-binding proteins

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9149%2802%2903270-8

Upregulation of endothelial nitric oxide synthase by HMG CoA reductase inhibitors

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9149%2802%2903270-8

Atherosclerotic Disease of the Aortic Arch and the Risk of Ischemic Stroke

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9149%2802%2903270-8

Mobile aortic atheroma and systemic emboli: efficacy of anticoagulation and influence of plaque morphology on recurrent stroke

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9149%2802%2903270-8

Effect of lovastatin on early carotid atherosclerosis and cardiovascular events. Asymptomatic Carotid Artery Progression Study (ACAPS) Research Group

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9149%2802%2903270-8

Pravastatin, Lipids, and Atherosclerosis in the Carotid Arteries (PLAC-II)

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9149%2802%2903270-8

Effects of pravastatin on thoracic aortic atherosclerosis in patients with heterozygous familial hypercholesterolemia

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9149%2802%2903270-8

Vascular effects of statins in stroke

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9149%2802%2903270-8

Regression of coronary artery disease as a result of intensive lipid-lowering therapy in men with high levels of apolipoprotein B

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9149%2802%2903270-8

Effects of monotherapy with an HMG-CoA reductase inhibitor on the progression of coronary atherosclerosis as assessed by serial quantitative arteriography. The Canadian Coronary Atherosclerosis Intervention Trial.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9149%2802%2903270-8

Statins do more than just lower cholesterol

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9149%2802%2903270-8

The evolving role of statins in the management of atherosclerosis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9149%2802%2903270-8

Atherosclerotic plaque rupture in symptomatic carotid artery stenosis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9149%2802%2903270-8

Effects of Fluvastatin on Leukocyte–Endothelial Cell Adhesion in Hypercholesterolemic Rats

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9149%2802%2903270-8

Oxidized LDL-induced leukocyte/endothelium interaction in vivo involves the receptor for platelet-activating factor

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9149%2802%2903270-8

HMG-CoA Reductase Inhibitors Decrease CD11b Expression and CD11b-Dependent Adhesion of Monocytes to Endothelium and Reduce Increased Adhesiveness of Monocytes Isolated From Patients With Hypercholesterolemia

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9149%2802%2903270-8

Interstitial Collagenase (MMP-1) Expression in Human Carotid Atherosclerosis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9149%2802%2903270-8

Statins alter smooth muscle cell accumulation and collagen content in established atheroma of watanabe heritable hyperlipidemic rabbits

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9149%2802%2903270-8

HMG-CoA reductase inhibitors reduce MMP-9 secretion by macrophages

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9149%2802%2903270-8

Vastatins Inhibit Tissue Factor in Cultured Human Macrophages

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9149%2802%2903270-8

Pravastatin treatment increases collagen content and decreases lipid content, inflammation, metalloproteinases, and cell death in human carotid plaques: implications for plaque stabilization

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9149%2802%2903270-8

The role of platelets in ischemic stroke

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9149%2802%2903270-8

Inhibition of thromboxane biosynthesis and platelet function by simvastatin in type IIa hypercholesterolemia

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9149%2802%2903270-8

Effects of long-term treatment with lovastatin on the clotting system and blood platelets

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9149%2802%2903270-8

Platelet cytosolic Ca2+ and membrane dynamics in patients with primary hypercholesterolemia. Effects of pravastatin

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9149%2802%2903270-8

Hyperlipidemia and coronary disease. Correction of the increased thrombogenic potential with cholesterol reduction

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9149%2802%2903270-8

Low-density lipoproteins inhibit the Na+/H+ antiport in human platelets. A novel mechanism enhancing platelet activity in hypercholesterolemia

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9149%2802%2903270-8

Elevated plasma levels of vascular endothelial cell markers in patients with hypercholesterolemia

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9149%2802%2903270-8

Platelet-dependent thrombin generation in patients with hyperlipidemia

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9149%2802%2903270-8

Oxidized low-density lipoprotein decreases the expression of endothelial nitric oxide synthase

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9149%2802%2903270-8

Stroke protection by 3-hydroxy-3-methylglutaryl (HMG)-CoA reductase inhibitors mediated by endothelial nitric oxide synthase

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9149%2802%2903270-8

Atorvastatin upregulates type III nitric oxide synthase in thrombocytes, decreases platelet activation, and protects from cerebral ischemia in normocholesterolemic mice

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9149%2802%2903270-8

Neuroprotection mediated by changes in the endothelial actin cytoskeleton.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9149%2802%2903270-8

The HMG-CoA reductase inhibitor simvastatin activates the protein kinase Akt and promotes angiogenesis in normocholesterolemic animals

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9149%2802%2903270-8

Activation of nitric oxide synthase in endothelial cells by Akt-dependent phosphorylation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9149%2802%2903270-8

Statins as a newly recognized type of immunomodulator

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9149%2802%2903270-8

Interleukin 1 (IL-1) induces biosynthesis and cell surface expression of procoagulant activity in human vascular endothelial cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9149%2802%2903270-8

Interleukin-1 beta mRNA expression in ischemic rat cortex

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9149%2802%2903270-8

Postischemic administration of an anti-Mac-1 antibody reduces ischemic cell damage after transient middle cerebral artery occlusion in rats

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9149%2802%2903270-8

Lovastatin and phenylacetate inhibit the induction of nitric oxide synthase and cytokines in rat primary astrocytes, microglia, and macrophages

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9149%2802%2903270-8

Neuroprotective properties of statins in cerebral ischemia and stroke

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9149%2802%2903270-8

Statins selectively inhibit leukocyte function antigen-1 by binding to a novel regulatory integrin site

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9149%2802%2903270-8

Gene dose of apolipoprotein E type 4 allele and the risk of Alzheimer's disease in late onset families

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9149%2802%2903270-8

Atherosclerosis, apolipoprotein E, and prevalence of dementia and Alzheimer's disease in the Rotterdam Study

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9149%2802%2903270-8

Lack of apolipoprotein E dramatically reduces amyloid beta-peptide deposition

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9149%2802%2903270-8

Serum total cholesterol, apolipoprotein E epsilon 4 allele, and Alzheimer's disease

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9149%2802%2903270-8

Interactions of apolipoprotein E genotype, total cholesterol level, age, and sex in prediction of Alzheimer's disease: a case-control study

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9149%2802%2903270-8

Decreased prevalence of Alzheimer disease associated with 3-hydroxy-3-methyglutaryl coenzyme A reductase inhibitors.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9149%2802%2903270-8

Statins and the risk of dementia

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9149%2802%2903270-8

The design of a prospective study of pravastatin in the elderly at risk (PROSPER)

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9149%2802%2903270-8

Simvastatin strongly reduces levels of Alzheimer's disease beta -amyloid peptides Abeta 42 and Abeta 40 in vitro and in vivo

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9149%2802%2903270-8

Low cholesterol stimulates the nonamyloidogenic pathway by its effect on the alpha -secretase ADAM 10.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9149%2802%2903270-8

A fluid connection: cholesterol and Abeta

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9149%2802%2903270-8

10.1016/S0002-9149(02)03270-8

7 January 2021

Identifiers

DOI

1 reference

6 August 2017

1 reference