Long-term gene therapy with thrombospondin 2 inhibits TGF-β activation, inflammation and angiogenesis in chronic allograft nephropathy (Q35078258)

6 August 2017

Long-term gene therapy with thrombospondin 2 inhibits TGF-β activation, inflammation and angiogenesis in chronic allograft nephropathy (English)

1 reference

chronic allograft nephropathy

6 August 2017

0 references

1 reference

Christoph Daniel

1

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author name string

Regina Vogelbacher

2

1 reference

6 August 2017

Andrea Stief

3

1 reference

6 August 2017

Christina Grigo

4

1 reference

6 August 2017

Christian Hugo

5

1 reference

6 August 2017

language of work or name

English

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publication date

23 December 2013

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6 August 2017

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6 August 2017

8

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6 August 2017

12

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6 August 2017

e83846

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Creative Commons Attribution 4.0 International

6 August 2017

start time

23 December 2013

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April 2022 Public Data File from Crossref

copyright status

copyrighted

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describes a project that uses

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3871554/fullTextXML

inferred from PubMed Central ID database lookup

cites work

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Thrombospondin-1 inhibits VEGF levels in the ovary directly by binding and internalization via the low density lipoprotein receptor-related protein-1 (LRP-1).

8 July 2018

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Everolimus inhibits glomerular endothelial cell proliferation and VEGF, but not long-term recovery in experimental thrombotic microangiopathy

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The tryptophan-rich motifs of the thrombospondin type 1 repeats bind VLAL motifs in the latent transforming growth factor-beta complex

8 July 2018

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Thrombospondin-1 is a major activator of TGF-beta in fibrotic renal disease in the rat in vivo.

8 July 2018

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8 July 2018

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Laser capture microdissection and real-time PCR for analysis of glomerular endothelin-1 gene expression in mesangiolysis of rat anti-Thy 1.1 and murine Habu Snake Venom glomerulonephritis

8 July 2018

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8 July 2018

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8 July 2018

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8 July 2018

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8 July 2018

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Altered extracellular matrix remodeling and angiogenesis in sponge granulomas of thrombospondin 2-null mice

8 July 2018

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Role of transforming growth factor-beta1 in the progression of chronic allograft nephropathy

8 July 2018

1 reference

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8 July 2018

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Mice that lack the angiogenesis inhibitor, thrombospondin 2, mount an altered foreign body reaction characterized by increased vascularity

8 July 2018

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8 July 2018

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Regulation of transforming growth factor-beta activation by discrete sequences of thrombospondin 1.

8 July 2018

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8 July 2018

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Participation of glomerular endothelial cells in the capillary repair of glomerulonephritis

8 July 2018

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Platelet-complement interactions in mesangial proliferative nephritis in the rat

8 July 2018

1 reference

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Transforming growth factor-β1 short hairpin RNA inhibits renal allograft fibrosis.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3871554

Renal allografts with IF/TA display distinct expression profiles of metzincins and related genes.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3871554

Identifying specific causes of kidney allograft loss.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3871554

Lack of improvement in renal allograft survival despite a marked decrease in acute rejection rates over the most recent era.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3871554

Matrix metalloproteinases (MMP9 and MMP2) induce the release of vascular endothelial growth factor (VEGF) by ovarian carcinoma cells: implications for ascites formation.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3871554

Accelerated wound healing in mice with a disruption of the thrombospondin 2 gene.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3871554

Establishment and characterization of a rat glomerular endothelial cell line.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3871554

Thrombospondin-2 prevents cardiac injury and dysfunction in viral myocarditis through the activation of regulatory T-cells

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3871554

TGF-beta1 in chronic allograft nephropathy following renal transplantation

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3871554

Interactions between CD47 and thrombospondin reduce inflammation

16 November 2018

1 reference

12 December 2020

Increased accumulation of extracellular thrombospondin-2 due to low degradation activity stimulates type I collagen expression in scleroderma fibroblasts

1 reference

12 December 2020

Impaired angiogenesis in the remnant kidney model: I. Potential role of vascular endothelial growth factor and thrombospondin-1

1 reference

12 December 2020

Thrombospondin 1 is expressed by proliferating mesangial cells and is up-regulated by PDGF and bFGF in vivo

1 reference

12 December 2020

The mTOR inhibitor everolimus attenuates the time course of chronic anti-Thy1 nephritis in the rat

1 reference

12 December 2020

Differential expression of profibrotic and growth factors in chronic allograft nephropathy

1 reference

12 December 2020

Sustained expression of thrombospondin-1 is associated with the development of glomerular and tubulointerstitial fibrosis in the remnant kidney model

1 reference

12 December 2020

Thrombospondin in renal disease

1 reference

12 December 2020

Thrombospondin 1 precedes and predicts the development of tubulointerstitial fibrosis in glomerular disease in the rat

1 reference

12 December 2020

Thrombopoietin and thrombospondin in renal allograft recipients

1 reference

12 December 2020

Absence of Thrombospondin-2 Causes Age-Related Dilated Cardiomyopathy

1 reference

12 December 2020

The activation sequence of thrombospondin-1 interacts with the latency-associated peptide to regulate activation of latent transforming growth factor-beta

1 reference

12 December 2020

10.1371/JOURNAL.PONE.0083846

Identifiers

DOI

1 reference

6 August 2017

0 references

1 reference

6 August 2017

1 reference