A sigmoidal transcriptional response: cooperativity, synergy and dosage effects (Q35079152)

6 August 2017

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title

A sigmoidal transcriptional response: cooperativity, synergy and dosage effects (English)

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6 August 2017

Reiner A Veitia

1

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6 August 2017

1 February 2003

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6 August 2017

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6 August 2017

78

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6 August 2017

1

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6 August 2017

149-170

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Quantitative model for gene regulation by lambda phage repressor

6 August 2017

1 reference

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Mutations in human TBX5 [corrected] cause limb and cardiac malformation in Holt-Oram syndrome

21 January 2018

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Cell signaling can direct either binary or graded transcriptional responses

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An enhanceosome containing the Jun B/Fra-2 heterodimer and the HMG-I(Y) architectural protein controls HPV 18 transcription

21 January 2018

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A murine model of Holt-Oram syndrome defines roles of the T-box transcription factor Tbx5 in cardiogenesis and disease

21 January 2018

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The enhanceosome and transcriptional synergy.

21 January 2018

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Nuclear compartments and gene regulation.

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Combinatorial codes in signaling and synergy: lessons from pituitary development

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Perturbation of nuclear architecture by long-distance chromosome interactions.

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A gradient of bicoid protein in Drosophila embryos

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The cardiac transcription factors Nkx2-5 and GATA-4 are mutual cofactors

21 January 2018

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Wrestling with pleiotropy: genomic and topological analysis of the yeast gene expression network.

21 January 2018

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Nuclear compartmentalization and gene activity

21 January 2018

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A functional enhancer suppresses silencing of a transgene and prevents its localization close to centrometric heterochromatin.

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Genomic profiling of drug sensitivities via induced haploinsufficiency.

21 January 2018

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Epistasis and pleiotropy as natural properties of transcriptional regulation.

21 January 2018

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RNA polymerase II holoenzyme and transcriptional regulation

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Tbx5 associates with Nkx2-5 and synergistically promotes cardiomyocyte differentiation

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On the attribution and additivity of binding energies

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Lethality and centrality in protein networks

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A model for reading morphogenetic gradients: autocatalysis and competition at the gene level

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A perspective into ligand-receptor affinities using complex numbers

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Comparison of Experimental Binding Data and Theoretical Models in Proteins Containing Subunits*

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WT-1 is required for early kidney development

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A genetic method for dissecting the mechanism of transcriptional activator synergy by identical activators

21 January 2018

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Compensatory energetic relationships between upstream activators and the RNA polymerase II general transcription machinery

21 January 2018

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How different eukaryotic transcriptional activators can cooperate promiscuously.

21 January 2018

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Evidence for stabilizing selection in a eukaryotic enhancer element.

21 January 2018

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A cell-specific nuclear receptor is essential for adrenal and gonadal development and sexual differentiation.

21 January 2018

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Transcriptional enhancers--on/off gene regulation as an adaptation to silencing in higher eukaryotic nuclei.

21 January 2018

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Nuclear receptor coactivators: multiple enzymes, multiple complexes, multiple functions.

21 January 2018

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Identifying regulatory networks by combinatorial analysis of promoter elements

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Synergistic transcription activation: a dual role for CRP in the activation of an Escherichia coli promoter depending on MalT and CRP

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Analysis of protein and DNA-mediated contributions to cooperative assembly of protein-DNA complexes

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The mutational spectrum in Waardenburg syndrome.

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Regulation of the Drosophila segmentation gene hunchback by two maternal morphogenetic centres

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Comparison of transcriptional synergy of estrogen receptors alpha and beta from multiple tandem estrogen response elements

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Estimating coarse gene network structure from large-scale gene perturbation data

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A mathematical model for synergistic eukaryotic gene activation.

21 January 2018

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Methylation of histone H4 at arginine 3 facilitating transcriptional activation by nuclear hormone receptor

21 January 2018

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Positional information and the spatial pattern of cellular differentiation

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The interaction of estradiol-receptor protein with the genome: an argument for the existence of undetected specific sites

21 January 2018

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21 January 2018

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The general affinity of lac repressor for E. coli DNA: Implications for gene regulation in procaryotes and eucaryotes

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A model for switch-like phenomena in biological systems

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Cooperative binding of steroid hormone receptors contributes to transcriptional synergism at target enhancer elements

21 January 2018

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Exploring the etiology of haploinsufficiency

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Genes regulated cooperatively by one or more transcription factors and their identification in whole eukaryotic genomes

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Quantitative DNase footprint titration: a method for studying protein-DNA interactions

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7 January 2021

Additivity principles in biochemistry

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Multiple layers of cooperativity regulate enhanceosome-responsive RNA polymerase II transcription complex assembly

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Cooperativity in enzyme function: equilibrium and kinetic aspects

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Nuclear RNA polymerases: role of general initiation factors and cofactors in eukaryotic transcription

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The molecular basis of genetic dominance

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Identifiers

DOI

1 reference

6 August 2017

1 reference

PubMed ID

12620064