Hydroxymalonyl-acyl carrier protein (ACP) and aminomalonyl-ACP are two additional type I polyketide synthase extender units (Q35080629)

6 August 2017

title

Hydroxymalonyl-acyl carrier protein (ACP) and aminomalonyl-ACP are two additional type I polyketide synthase extender units (English)

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6 August 2017

5

Jo Handelsman

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6 August 2017

4

Amy K Klimowicz

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6 August 2017

Yolande A Chan

1

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6 August 2017

Michael T Boyne

2

1 reference

6 August 2017

Angela M Podevels

3

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6 August 2017

Neil L Kelleher

6

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6 August 2017

Michael G Thomas

7

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6 August 2017

language of work or name

English

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publication date

18 September 2006

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Proceedings of the National Academy of Sciences of the United States of America

6 August 2017

published in

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6 August 2017

volume

103

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6 August 2017

issue

39

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6 August 2017

page(s)

14349-14354

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Mechanisms for incorporation of glycerol-derived precursors into polyketide metabolites

6 August 2017

cites work

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Insights into the biosynthesis of the benzoquinone ansamycins geldanamycin and herbimycin, obtained by gene sequencing and disruption

8 July 2018

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Construction of a hybrid quadrupole/Fourier transform ion cyclotron resonance mass spectrometer for versatile MS/MS above 10 kDa.

8 July 2018

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Genetics of zwittermicin a production by Bacillus cereus

8 July 2018

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Crystal structure of an Acyl-ACP dehydrogenase from the FK520 polyketide biosynthetic pathway: insights into extender unit biosynthesis

8 July 2018

1 reference

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Aminomalonate as an enzyme inhibitor

8 July 2018

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Characterization of the biosynthetic gene cluster for the antifungal polyketide soraphen A from Sorangium cellulosum So ce26.

8 July 2018

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Type I polyketide biosynthesis in bacteria (part B).

8 July 2018

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BeF(3)(-) acts as a phosphate analog in proteins phosphorylated on aspartate: structure of a BeF(3)(-) complex with phosphoserine phosphatase

8 July 2018

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Crystal structure of phosphoserine phosphatase from Methanococcus jannaschii, a hyperthermophile, at 1.8 A resolution

8 July 2018

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Multiple genetic modifications of the erythromycin polyketide synthase to produce a library of novel "unnatural" natural products.

8 July 2018

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A new class of phosphotransferases phosphorylated on an aspartate residue in an amino-terminal DXDX(T/V) motif

8 July 2018

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Modular structure of peptide synthetases revealed by dissection of the multifunctional enzyme GrsA.

8 July 2018

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Infrared multiphoton dissociation of large multiply charged ions for biomolecule sequencing

8 July 2018

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Extension of dynamic range in Fourier transform ion cyclotron resonance mass spectrometry via stored waveform inverse Fourier transform excitation

8 July 2018

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The FK520 gene cluster of Streptomyces hygroscopicus var. ascomyceticus (ATCC 14891) contains genes for biosynthesis of unusual polyketide extender units

8 July 2018

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Cloning and characterization of a gene cluster for geldanamycin production in Streptomyces hygroscopicus NRRL 3602.

21 January 2018

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Identification of a set of genes involved in the formation of the substrate for the incorporation of the unusual "glycolate" chain extension unit in ansamitocin biosynthesis

21 January 2018

1 reference

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Engineered biosynthesis of 16-membered macrolides that require methoxymalonyl-ACP precursors in Streptomyces fradiae

21 January 2018

1 reference

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Antibiotics GE23077, novel inhibitors of bacterial RNA polymerase. I. Taxonomy, isolation and characterization

21 January 2018

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Understanding substrate specificity of polyketide synthase modules by generating hybrid multimodular synthases.

21 January 2018

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Conversion of L-proline to pyrrolyl-2-carboxyl-S-PCP during undecylprodigiosin and pyoluteorin biosynthesis

21 January 2018

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Automated reduction and interpretation of high resolution electrospray mass spectra of large molecules.

21 January 2018

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Web and database software for identification of intact proteins using "top down" mass spectrometry

21 January 2018

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The bifunctional glyceryl transferase/phosphatase OzmB belonging to the HAD superfamily that diverts 1,3-bisphosphoglycerate into polyketide biosynthesis

21 January 2018

1 reference

12 December 2020

Functional expression of genes involved in the biosynthesis of the novel polyketide chain extension unit, methoxymalonyl-acyl carrier protein, and engineered biosynthesis of 2-desmethyl-2-methoxy-6-deoxyerythronolide B

1 reference

12 December 2020

Divergent sequence motifs correlated with the substrate specificity of (methyl)malonyl-CoA:acyl carrier protein transacylase domains in modular polyketide synthases

1 reference

12 December 2020

Characterization of Sfp, a Bacillus subtilis phosphopantetheinyl transferase for peptidyl carrier protein domains in peptide synthetases

1 reference

12 December 2020

Identifiers

DOI

10.1073/PNAS.0603748103

1 reference

6 August 2017

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6 August 2017

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