Normal-repeat-length polyglutamine peptides accelerate aggregation nucleation and cytotoxicity of expanded polyglutamine proteins (Q35080634)

6 August 2017

Normal-repeat-length polyglutamine peptides accelerate aggregation nucleation and cytotoxicity of expanded polyglutamine proteins (English)

1 reference

6 August 2017

0 references

Natalia Slepko

1

1 reference

6 August 2017

Anusri M Bhattacharyya

2

1 reference

6 August 2017

George R Jackson

3

1 reference

6 August 2017

Joan S Steffan

4

1 reference

6 August 2017

J Lawrence Marsh

5

1 reference

6 August 2017

Leslie Michels Thompson

6

1 reference

6 August 2017

Ronald Wetzel

7

1 reference

6 August 2017

language of work or name

English

0 references

publication date

15 September 2006

1 reference

Proceedings of the National Academy of Sciences of the United States of America

6 August 2017

1 reference

6 August 2017

103

1 reference

6 August 2017

39

1 reference

6 August 2017

14367-14372

1 reference

polyglutamine aggregation nucleation: thermodynamics of a highly unfavorable protein folding reaction

6 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1599969

Spinocerebellar ataxia type 2: polyQ repeat variation in the CACNA1A calcium channel modifies age of onset

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1599969

Identification of combinatorial drug regimens for treatment of Huntington's disease using Drosophila.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1599969

Inclusion body formation reduces levels of mutant huntingtin and the risk of neuronal death

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1599969

Evidence for a modifier of onset age in Huntington disease linked to the HD gene in 4p16.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1599969

Venezuelan kindreds reveal that genetic and environmental factors modulate Huntington's disease age of onset

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1599969

A genome scan for modifiers of age at onset in Huntington disease: The HD MAPS study.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1599969

Aberrant histone acetylation, altered transcription, and retinal degeneration in a Drosophila model of polyglutamine disease are rescued by CREB-binding protein

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1599969

Common structure of soluble amyloid oligomers implies common mechanism of pathogenesis

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1599969

Huntington's disease age-of-onset linked to polyglutamine aggregation nucleation

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1599969

Histone deacetylase inhibitors arrest polyglutamine-dependent neurodegeneration in Drosophila

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1599969

Solubilization and disaggregation of polyglutamine peptides

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1599969

Self-assembly of polyglutamine-containing huntingtin fragments into amyloid-like fibrils: implications for Huntington's disease pathology

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1599969

Recruitment and the role of nuclear localization in polyglutamine-mediated aggregation

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1599969

Aggregation of huntingtin in neuronal intranuclear inclusions and dystrophic neurites in brain

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1599969

cDNAs with long CAG trinucleotide repeats from human brain

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1599969

Polyglutamine aggregation behavior in vitro supports a recruitment mechanism of cytotoxicity

8 July 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0602348103

Huntingtin-encoded polyglutamine expansions form amyloid-like protein aggregates in vitro and in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0602348103

Amyloid-like features of polyglutamine aggregates and their assembly kinetics

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0602348103

Huntingtin spheroids and protofibrils as precursors in polyglutamine fibrilization

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0602348103

Hsp70 and Hsp40 attenuate formation of spherical and annular polyglutamine oligomers by partitioning monomer

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0602348103

Assembly of amyloid protofibrils via critical oligomers--a novel pathway of amyloid formation

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0602348103

Protofibril formation of amyloid beta-protein at low pH via a non-cooperative elongation mechanism.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0602348103

Analysis of protein aggregation kinetics.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0602348103

Seeding specificity in amyloid growth induced by heterologous fibrils

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0602348103

Amyloid formation by mutant huntingtin: threshold, progressivity and recruitment of normal polyglutamine proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0602348103

A role for selection in regulating the evolutionary emergence of disease-causing and other coding CAG repeats in humans and mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0602348103

An exhaustive DNA micro-satellite map of the human genome using high performance computing.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0602348103

Oligoproline effects on polyglutamine conformation and aggregation

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0602348103

Use of gene knockouts in cultured cells to study apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0602348103

Modulation of the light response by cAMP in Drosophila photoreceptors.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1599969

Kinetic analysis of amyloid fibril formation

27 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/16980414

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Kinetics and thermodynamics of amyloid assembly using a high-performance liquid chromatography-based sedimentation assay

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/16980414

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Interference by huntingtin and atrophin-1 with cbp-mediated transcription leading to cellular toxicity

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/16980414

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1073/PNAS.0602348103

1 reference

6 August 2017

0 references

1 reference

6 August 2017

1 reference