Activation of Rho-associated coiled-coil protein kinase 1 (ROCK-1) by caspase-3 cleavage plays an essential role in cardiac myocyte apoptosis (Q35080715)

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scholarly article

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English	Activation of Rho-associated coiled-coil protein kinase 1 (ROCK-1) by caspase-3 cleavage plays an essential role in cardiac myocyte apoptosis	scholarly article

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scholarly article

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30 December 2019

Activation of Rho-associated coiled-coil protein kinase 1 (ROCK-1) by caspase-3 cleavage plays an essential role in cardiac myocyte apoptosis (English)

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30 December 2019

apoptotic process

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Michael D Schneider

4

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30 December 2019

6

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Lei Wei

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30 December 2019

author name string

Jiang Chang

1

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30 December 2019

Min Xie

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30 December 2019

Viraj R Shah

3

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30 December 2019

Mark L Entman

5

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30 December 2019

Robert J Schwartz

7

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30 December 2019

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18 September 2006

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30 December 2019

Proceedings of the National Academy of Sciences of the United States of America

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30 December 2019

103

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30 December 2019

39

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30 December 2019

14495-14500

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30 December 2019

Decreased perivascular fibrosis but not cardiac hypertrophy in ROCK1+/- haploinsufficient mice

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8 July 2018

Regulation of PTEN by Rho small GTPases

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Death begets failure in the heart

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PTEN as an effector in the signaling of antimigratory G protein-coupled receptor

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ROCK-I regulates closure of the eyelids and ventral body wall by inducing assembly of actomyosin bundles

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The role of phosphoinositide-3 kinase and PTEN in cardiovascular physiology and disease

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Protein kinase A in complex with Rho-kinase inhibitors Y-27632, Fasudil, and H-1152P: structural basis of selectivity

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8 July 2018

Sizing up the heart: development redux in disease.

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8 July 2018

Rocks: multifunctional kinases in cell behaviour

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8 July 2018

A mechanistic role for cardiac myocyte apoptosis in heart failure

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8 July 2018

Telomere attrition and Chk2 activation in human heart failure

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8 July 2018

Myocyte death, growth, and regeneration in cardiac hypertrophy and failure

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8 July 2018

Cytosolic retention of phosphorylated extracellular signal-regulated kinase and a Rho-associated kinase-mediated signal impair expression of p21(Cip1/Waf1) in phorbol 12-myristate-13- acetate-induced apoptotic cells

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8 July 2018

Noninvasive cardiovascular phenotyping in mice

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8 July 2018

The phosphoinositide 3-kinase pathway

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8 July 2018

Apoptosis and the systolic dysfunction in congestive heart failure. Story of apoptosis interruptus and zombie myocytes

1 reference

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8 July 2018

Caspase-3-mediated cleavage of ROCK I induces MLC phosphorylation and apoptotic membrane blebbing

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8 July 2018

Membrane blebbing during apoptosis results from caspase-mediated activation of ROCK I.

1 reference

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8 July 2018

Regulation and functions of Rho-associated kinase

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8 July 2018

Pharmacological properties of Y-27632, a specific inhibitor of rho-associated kinases

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Expression of heat shock proteins in turtle and mammal hearts: relationship to anoxia tolerance

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Apoptosis in heart failure: release of cytochrome c from mitochondria and activation of caspase-3 in human cardiomyopathy

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8 July 2018

Postmitochondrial regulation of apoptosis during heart failure

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8 July 2018

Enhanced Galphaq signaling: a common pathway mediates cardiac hypertrophy and apoptotic heart failure

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8 July 2018

Calcium sensitization of smooth muscle mediated by a Rho-associated protein kinase in hypertension

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Rho GTPases and signaling networks

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p160ROCK, a Rho-associated coiled-coil forming protein kinase, works downstream of Rho and induces focal adhesions

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Small GTP-binding proteins and the regulation of the actin cytoskeleton

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Tissue-specific regulation of the alpha-myosin heavy chain gene promoter in transgenic mice.

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Rho-kinase inhibitor improves increased vascular resistance and impaired vasodilation of the forearm in patients with heart failure

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Inhibition of Rho-kinase protects the heart against ischemia/reperfusion injury.

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27 September 2018

Caspase activation during phorbol ester-induced apoptosis requires ROCK-dependent myosin-mediated contraction

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Galpha11 induces caspase-mediated proteolytic activation of Rho-associated kinase, ROCK-I, in HeLa cells

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Adenovirus-mediated transfer of inducible caspases: a novel "death switch" gene therapeutic approach to prostate cancer

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Targeted deletion of ROCK1 protects the heart against pressure overload by inhibiting reactive fibrosis

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12 December 2020

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The tumor suppressor gene PTEN can regulate cardiac hypertrophy and survival

1 reference

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12 December 2020

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Central involvement of Rho family GTPases in TNF-alpha-mediated bovine pulmonary endothelial cell apoptosis

1 reference

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12 December 2020

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Inhibitory cardiac transcription factor, SRF-N, is generated by caspase 3 cleavage in human heart failure and attenuated by ventricular unloading

1 reference

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Apoptosis in myocytes in end-stage heart failure

1 reference

https://pubmed.ncbi.nlm.nih.gov/16983089

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Apoptosis in the failing human heart

1 reference

https://pubmed.ncbi.nlm.nih.gov/16983089

12 December 2020

based on heuristic

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Identifiers

10.1073/PNAS.0601911103

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30 December 2019

2006PNAS..10314495C

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30 December 2019

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30 December 2019

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