Design strategies to improve soluble macromolecular delivery constructs (Q35082134)

6 August 2017

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title

Design strategies to improve soluble macromolecular delivery constructs (English)

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6 August 2017

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Christie RJ

1

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PubMed ID

12628325

6 August 2017

Grainger DW

series ordinal

2

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PubMed ID

12628325

6 August 2017

language of work or name

English

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publication date

1 February 2003

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Advanced Drug Delivery Reviews

6 August 2017

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6 August 2017

55

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6 August 2017

3

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6 August 2017

421-437

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Stabilization of substances in circulation

6 August 2017

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2802%2900229-6

7 January 2021

Polymeric systems for controlled drug release

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2802%2900229-6

7 January 2021

Genetically engineered polymers for drug delivery

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2802%2900229-6

7 January 2021

Designing peptide-based scaffolds as drug delivery vehicles

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2802%2900229-6

7 January 2021

Design of novel bioconjugates for targeted drug delivery

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2802%2900229-6

7 January 2021

HPMA copolymer-anticancer drug conjugates: design, activity, and mechanism of action

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2802%2900229-6

7 January 2021

Water soluble polymers in tumor targeted delivery

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2802%2900229-6

7 January 2021

Endogenous carriers and ligands in non-immunogenic site-specific drug delivery

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2802%2900229-6

7 January 2021

Control of tumour vascular permeability

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2802%2900229-6

7 January 2021

Tumor vascular permeability and the EPR effect in macromolecular therapeutics: a review

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2802%2900229-6

7 January 2021

A tumor-homing peptide with a targeting specificity related to lymphatic vessels

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2802%2900229-6

7 January 2021

Endosomes, lysosomes: their implication in gene transfer

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2802%2900229-6

7 January 2021

Lysosomal cysteine proteases: facts and opportunities

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2802%2900229-6

7 January 2021

Differences in the intracellular fate of free and polymer-bound doxorubicin

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2802%2900229-6

7 January 2021

Polymer-drug conjugates, PDEPT and PELT: basic principles for design and transfer from the laboratory to clinic

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2802%2900229-6

7 January 2021

Exploitation of intracellular pH gradients in the cellular delivery of macromolecules

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2802%2900229-6

7 January 2021

Quantitative measurement of intraorganelle pH in the endosomal-lysosomal pathway in neurons by using ratiometric imaging with pyranine

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2802%2900229-6

7 January 2021

Synthesis, characterization, and application of fluorescence sensing lipobeads for intracellular pH measurements

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2802%2900229-6

7 January 2021

Drug-polymer conjugates containing acid-cleavable bonds

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2802%2900229-6

7 January 2021

New HPMA copolymers containing doxorubicin bound via pH-sensitive linkage: synthesis and preliminary in vitro and in vivo biological properties

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2802%2900229-6

7 January 2021

Monoclonal antibody conjugates of doxorubicin prepared with branched linkers: A novel method for increasing the potency of doxorubicin immunoconjugates

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2802%2900229-6

7 January 2021

Targeted delivery of doxorubicin by HPMA copolymer-hyaluronan bioconjugates

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2802%2900229-6

7 January 2021

Cis-aconityl spacer between daunomycin and macromolecular carriers: A model of pH-sensitive linkage releasing drug from a lysosomotropic conjugate

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2802%2900229-6

7 January 2021

Doxorubicin conjugated with a monoclonal antibody directed to a human melanoma-associated proteoglycan suppresses the growth of established tumor xenografts in nude mice

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2802%2900229-6

7 January 2021

Lysosome membrane permeability: implications for drug delivery

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2802%2900229-6

7 January 2021

Influence of membrane-active peptides on lipospermine/DNA complex mediated gene transfer.

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2802%2900229-6

7 January 2021

Bacterial pore-forming hemolysins and their use in the cytosolic delivery of macromolecules

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2802%2900229-6

7 January 2021

Application of membrane-active peptides for nonviral gene delivery

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2802%2900229-6

7 January 2021

Receptor binding and membrane fusion in virus entry: the influenza hemagglutinin

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2802%2900229-6

7 January 2021

Mechanism of leakage of phospholipid vesicle contents induced by the peptide GALA.

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2802%2900229-6

7 January 2021

Characterization of a novel pH-sensitive peptide that enhances drug release from folate-targeted liposomes at endosomal pHs.

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2802%2900229-6

7 January 2021

Synthesis and characterization of membrane-active GALA-OKT9 conjugates

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2802%2900229-6

7 January 2021

Effect of cholesterol and charge on pore formation in bilayer vesicles by a pH-sensitive peptide

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2802%2900229-6

7 January 2021

Effect of phospholipid composition on an amphipathic peptide-mediated pore formation in bilayer vesicles

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2802%2900229-6

7 January 2021

Transfection of human macrophages by lipoplexes via the combined use of transferrin and pH-sensitive peptides

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2802%2900229-6

7 January 2021

Polyamidoamine cascade polymers mediate efficient transfection of cells in culture

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2802%2900229-6

7 January 2021

Design, synthesis, and characterization of a cationic peptide that binds to nucleic acids and permeabilizes bilayers.

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2802%2900229-6

7 January 2021

Tamoxifen inhibits acidification in cells independent of the estrogen receptor

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2802%2900229-6

7 January 2021

Maximizing the in vivo efficiency of gene transfer by means of nonviral polymeric gene delivery vehicles

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2802%2900229-6

7 January 2021

Effects of membrane-active agents in gene delivery

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2802%2900229-6

7 January 2021

Role of endocytosis in the transfection of L929 fibroblasts by polyethylenimine/DNA complexes

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2802%2900229-6

7 January 2021

Recent progress in gene delivery using non-viral transfer complexes

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2802%2900229-6

7 January 2021

Interaction of a cationic polymer with negatively charged proteoliposomes.

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2802%2900229-6

7 January 2021

Activation of the complement system by synthetic DNA complexes: a potential barrier for intravenous gene delivery.

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2802%2900229-6

7 January 2021

Dendrimers: relationship between structure and biocompatibility in vitro, and preliminary studies on the biodistribution of 125I-labelled polyamidoamine dendrimers in vivo

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2802%2900229-6

7 January 2021

Histidine-rich peptides and polymers for nucleic acids delivery

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2802%2900229-6

7 January 2021

Polymer-based gene delivery with low cytotoxicity by a unique balance of side-chain termini

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2802%2900229-6

7 January 2021

Histidylated oligolysines increase the transmembrane passage and the biological activity of antisense oligonucleotides

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2802%2900229-6

7 January 2021

Efficient gene transfer by histidylated polylysine/pDNA complexes

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2802%2900229-6

7 January 2021

pH-sensitive cationic polymer gene delivery vehicle: N-Ac-poly(L-histidine)-graft-poly(L-lysine) comb shaped polymer

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2802%2900229-6

7 January 2021

Membrane solubilization by a hydrophobic polyelectrolyte: surface activity and membrane binding

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2802%2900229-6

7 January 2021

The design and synthesis of polymers for eukaryotic membrane disruption.

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2802%2900229-6

7 January 2021

Hemolytic activity of pH-responsive polymer-streptavidin bioconjugates

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2802%2900229-6

7 January 2021

A pH-sensitive polymer that enhances cationic lipid-mediated gene transfer

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2802%2900229-6

7 January 2021

Translocating peptides and proteins and their use for gene delivery.

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2802%2900229-6

7 January 2021

Protein transduction: unrestricted delivery into all cells?

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2802%2900229-6

7 January 2021

Cellular delivery of impermeable effector molecules in the form of conjugates with peptides capable of mediating membrane translocation.

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2802%2900229-6

7 January 2021

A Truncated HIV-1 Tat Protein Basic Domain Rapidly Translocates through the Plasma Membrane and Accumulates in the Cell Nucleus

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2802%2900229-6

7 January 2021

The HIV-1 Tat nuclear localization sequence confers novel nuclear import properties

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2802%2900229-6

7 January 2021

Vectorial delivery of macromolecules into cells using peptide-based vehicles

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2802%2900229-6

7 January 2021

The design, synthesis, and evaluation of molecules that enable or enhance cellular uptake: peptoid molecular transporters

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2802%2900229-6

7 January 2021

Tumor cell retention of antibody Fab fragments is enhanced by an attached HIV TAT protein-derived peptide

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2802%2900229-6

7 January 2021

Tat-mediated delivery of heterologous proteins into cells

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2802%2900229-6

7 January 2021

Tat peptide-derivatized magnetic nanoparticles allow in vivo tracking and recovery of progenitor cells.

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2802%2900229-6

7 January 2021

Ability of the Tat basic domain and VP22 to mediate cell binding, but not membrane translocation of the diphtheria toxin A-fragment

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2802%2900229-6

7 January 2021

Trojan peptides: the penetratin system for intracellular delivery

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2802%2900229-6

7 January 2021

Conformational states of the cell-penetrating peptide penetratin when interacting with phospholipid vesicles: effects of surface charge and peptide concentration

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2802%2900229-6

7 January 2021

Interaction and structure induction of cell-penetrating peptides in the presence of phospholipid vesicles

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2802%2900229-6

7 January 2021

Internalization of HIV-1 tat requires cell surface heparan sulfate proteoglycans

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2802%2900229-6

7 January 2021

Different mechanisms for cellular internalization of the HIV-1 Tat-derived cell penetrating peptide and recombinant proteins fused to Tat.

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2802%2900229-6

7 January 2021

Cell internalization of the third helix of the Antennapedia homeodomain is receptor-independent.

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2802%2900229-6

7 January 2021

Cargo delivery kinetics of cell-penetrating peptides

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2802%2900229-6

7 January 2021

Arginine-rich peptides. An abundant source of membrane-permeable peptides having potential as carriers for intracellular protein delivery

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2802%2900229-6

7 January 2021

Quantitation of the Tumor-Targeting Properties of Antibody Fragments Conjugated to Cell-Permeating HIV-1 TAT Peptides

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2802%2900229-6

7 January 2021

Macromolecular exchanges between the nucleus and cytoplasm.

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2802%2900229-6

7 January 2021

Transport between the cell nucleus and the cytoplasm

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2802%2900229-6

7 January 2021

Molecular mechanism of translocation through nuclear pore complexes during nuclear protein import.

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2802%2900229-6

7 January 2021

Nuclear import of polypeptides, polynucleotides and supramolecular complexes

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2802%2900229-6

7 January 2021

Nucleocytoplasmic transport: the soluble phase

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2802%2900229-6

7 January 2021

Nuclear targeting of proteins: how many different signals?

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2802%2900229-6

7 January 2021

Dissection of a nuclear localization signal

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2802%2900229-6

7 January 2021

Kinetics and mechanism of DNA uptake into the cell nucleus

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2802%2900229-6

7 January 2021

Gene delivery: a single nuclear localization signal peptide is sufficient to carry DNA to the cell nucleus

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2802%2900229-6

7 January 2021

Ability of the hydrophobic FGF and basic TAT peptides to promote cellular uptake of recombinant Cre recombinase: a tool for efficient genetic engineering of mammalian genomes

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2802%2900229-6

7 January 2021

Improvement of Porphyrin Cellular Delivery and Activity by Conjugation to a Carrier Peptide

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2802%2900229-6

7 January 2021

Recent advances in cellular, sub-cellular and molecular targeting

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2802%2900229-6

7 January 2021

Drug delivery to mitochondria: the key to mitochondrial medicine

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2802%2900229-6

7 January 2021

10.1016/S0169-409X(02)00229-6

Identifiers

DOI

1 reference

6 August 2017

1 reference

PubMed ID

12628325