Tumour suppressor SIRT3 deacetylates and activates manganese superoxide dismutase to scavenge ROS (Q35082662)

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31 January 2020

title

Tumour suppressor SIRT3 deacetylates and activates manganese superoxide dismutase to scavenge ROS (English)

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4

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author name string

Yaohui Chen

1

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31 January 2020

Jinye Zhang

2

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Yan Lin

3

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Kun-Liang Guan

5

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Shimin Zhao

6

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Yue Xiong

7

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publication date

13 May 2011

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31 January 2020

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volume

12

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issue

6

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page(s)

534-541

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Sirt3-mediated deacetylation of evolutionarily conserved lysine 122 regulates MnSOD activity in response to stress.

31 January 2020

cites work

1 reference

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Calorie restriction reduces oxidative stress by SIRT3-mediated SOD2 activation

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3128277

Regulation of intermediary metabolism by protein acetylation

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3128277

Regulation of cellular metabolism by protein lysine acetylation

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3128277

SIRT3 is a mitochondria-localized tumor suppressor required for maintenance of mitochondrial integrity and metabolism during stress

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3128277

Lysine acetylation targets protein complexes and co-regulates major cellular functions

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3128277

Regulation of superoxide dismutase genes: implications in disease

8 July 2018

1 reference

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Mechanisms and molecular probes of sirtuins.

8 July 2018

1 reference

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Lysine acetylation: codified crosstalk with other posttranslational modifications

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3128277

Mammalian Sir2 homolog SIRT3 regulates global mitochondrial lysine acetylation

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3128277

Substrate and functional diversity of lysine acetylation revealed by a proteomics survey

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3128277

The Sir2 family of protein deacetylases

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3128277

Oxidants, oxidative stress and the biology of ageing

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3128277

The structure of human mitochondrial manganese superoxide dismutase reveals a novel tetrameric interface of two 4-helix bundles

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3128277

8 July 2018

Identifiers

DOI

10.1038/EMBOR.2011.65

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31 January 2020

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31 January 2020

PubMed publication ID

21566644

1 reference