Sequential therapy with JX-594, a targeted oncolytic poxvirus, followed by sorafenib in hepatocellular carcinoma: preclinical and clinical demonstration of combination efficacy (Q35086690)

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English	Sequential therapy with JX-594, a targeted oncolytic poxvirus, followed by sorafenib in hepatocellular carcinoma: preclinical and clinical demonstration of combination efficacy	scientific article

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scholarly article

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26 January 2020

Sequential therapy with JX-594, a targeted oncolytic poxvirus, followed by sorafenib in hepatocellular carcinoma: preclinical and clinical demonstration of combination efficacy (English)

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26 January 2020

oncolytic virus

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inferred from title

hepatocellular carcinoma

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based on heuristic

inferred from title

12

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26 January 2020

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John C Bell

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26 January 2020

author name string

Jeong Heo

1

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26 January 2020

Caroline J Breitbach

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26 January 2020

Anne Moon

3

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26 January 2020

Chang Won Kim

4

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26 January 2020

Rick Patt

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26 January 2020

Mi Kyung Kim

6

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26 January 2020

Yu Kyung Lee

7

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26 January 2020

Sung Yong Oh

8

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26 January 2020

Hyun Young Woo

9

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26 January 2020

Kelley Parato

10

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26 January 2020

Julia Rintoul

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26 January 2020

Theresa Hickman

13

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26 January 2020

Byung-Geon Rhee

14

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26 January 2020

David H Kirn

16

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26 January 2020

Tae-Ho Hwang

17

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26 January 2020

publication date

22 March 2011

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26 January 2020

Molecular Therapy

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26 January 2020

19

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26 January 2020

6

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26 January 2020

1170-1179

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26 January 2020

Antiangiogenic cancer therapy combined with oncolytic virotherapy leads to regression of established tumors in mice

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8 July 2018

Modified RECIST (mRECIST) assessment for hepatocellular carcinoma

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8 July 2018

The expression of VEGF receptor genes is concurrently influenced by epigenetic gene silencing of the genes and VEGF activation

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8 July 2018

Efficacy and safety of sorafenib in patients in the Asia-Pacific region with advanced hepatocellular carcinoma: a phase III randomised, double-blind, placebo-controlled trial

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8 July 2018

Transient high glucose causes persistent epigenetic changes and altered gene expression during subsequent normoglycemia

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8 July 2018

Sorafenib in advanced hepatocellular carcinoma

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8 July 2018

Use of a targeted oncolytic poxvirus, JX-594, in patients with refractory primary or metastatic liver cancer: a phase I trial

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8 July 2018

Development of a rapid and sensitive LC-MS/MS assay for the determination of sorafenib in human plasma

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8 July 2018

Targeting of interferon-beta to produce a specific, multi-mechanistic oncolytic vaccinia virus

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8 July 2018

Targeted inflammation during oncolytic virus therapy severely compromises tumor blood flow

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8 July 2018

Correlation of computed tomography and positron emission tomography in patients with metastatic gastrointestinal stromal tumor treated at a single institution with imatinib mesylate: proposal of new computed tomography response criteria.

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8 July 2018

Epigenetic changes in estrogen receptor beta gene in atherosclerotic cardiovascular tissues and in-vitro vascular senescence

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8 July 2018

Systemic armed oncolytic and immunologic therapy for cancer with JX-594, a targeted poxvirus expressing GM-CSF.

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8 July 2018

Disabling poxvirus pathogenesis by inhibition of Abl-family tyrosine kinases

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8 July 2018

Antiviral chemotherapy facilitates control of poxvirus infections through inhibition of cellular signal transduction

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8 July 2018

Vaccinia virus intermediate stage transcription is complemented by Ras-GTPase-activating protein SH3 domain-binding protein (G3BP) and cytoplasmic activation/proliferation-associated protein (p137) individually or as a heterodimer

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BAY 43-9006 exhibits broad spectrum oral antitumor activity and targets the RAF/MEK/ERK pathway and receptor tyrosine kinases involved in tumor progression and angiogenesis

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8 July 2018

Discovery of a novel Raf kinase inhibitor

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8 July 2018

Exploiting tumor-specific defects in the interferon pathway with a previously unknown oncolytic virus

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8 July 2018

New guidelines to evaluate the response to treatment in solid tumors. European Organization for Research and Treatment of Cancer, National Cancer Institute of the United States, National Cancer Institute of Canada

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Thymidine kinase expression. A marker for malignant cells.

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Prognostic factors for progression-free and overall survival with sunitinib targeted therapy and with cytokine as first-line therapy in patients with metastatic renal cell carcinoma

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27 September 2018

The targeted oncolytic poxvirus JX-594 demonstrates antitumoral, antivascular, and anti-HBV activities in patients with hepatocellular carcinoma

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27 September 2018

Cell cycle dependent and schedule-dependent antitumor effects of sorafenib combined with radiation

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Validation of a liquid chromatography assay for the quantification of the Raf kinase inhibitor BAY 43-9006 in small volumes of mouse serum

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GM-CSF and TNF-α cooperate in the generation of dendritic Langerhans cells

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based on heuristic

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Phase II study of sorafenib in patients with advanced hepatocellular carcinoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/21427706

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A rapid and sensitive method for determination of sorafenib in human plasma using a liquid chromatography/tandem mass spectrometry assay

1 reference

https://pubmed.ncbi.nlm.nih.gov/21427706

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1038/MT.2011.39

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26 January 2020

1 reference

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26 January 2020

1 reference

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26 January 2020

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