Sequencing the head and neck cancer genome: implications for therapy (Q35087559)

6 August 2017

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title

Sequencing the head and neck cancer genome: implications for therapy (English)

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6 August 2017

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1 reference

head and neck carcinoma

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Wenyue Sun

1

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Joseph A Califano

series ordinal

2

object named as

Joseph A Califano

1 reference

6 August 2017

language of work or name

English

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publication date

1 December 2014

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Annals of the New York Academy of Sciences

6 August 2017

published in

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6 August 2017

volume

1333

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6 August 2017

page(s)

33-42

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Characterization of HPV and host genome interactions in primary head and neck cancers

6 August 2017

cites work

1 reference

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Multi-tiered genomic analysis of head and neck cancer ties TP53 mutation to 3p loss

8 July 2018

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Clinical, genomic, and metagenomic characterization of oral tongue squamous cell carcinoma in patients who do not smoke

8 July 2018

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Squamous cell carcinoma of the oral tongue in young non-smokers is genomically similar to tumors in older smokers.

8 July 2018

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Novel insight into mutational landscape of head and neck squamous cell carcinoma

8 July 2018

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Contribution of p53 to metastasis

8 July 2018

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From fly wings to targeted cancer therapies: a centennial for notch signaling

8 July 2018

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Reverse-phase protein array profiling of oropharyngeal cancer and significance of PIK3CA mutations in HPV-associated head and neck cancer

8 July 2018

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Genomic analysis of head and neck squamous cell carcinoma cell lines and human tumors: a rational approach to preclinical model selection.

8 July 2018

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Activation of the NOTCH pathway in head and neck cancer

8 July 2018

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Common and complex Notch1 mutations in Chinese oral squamous cell carcinoma

8 July 2018

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Mutational landscape and significance across 12 major cancer types

8 July 2018

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TP53 mutation and human papilloma virus status of oral squamous cell carcinomas in young adult patients.

8 July 2018

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Exploiting the head and neck cancer oncogenome: widespread PI3K-mTOR pathway alterations and novel molecular targets

8 July 2018

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Targeted next-generation sequencing of head and neck squamous cell carcinoma identifies novel genetic alterations in HPV+ and HPV- tumors

8 July 2018

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p53-based therapeutics for head and neck squamous cell carcinoma

8 July 2018

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Integrative genomic characterization of oral squamous cell carcinoma identifies frequent somatic drivers

8 July 2018

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Frequent mutation of the PI3K pathway in head and neck cancer defines predictive biomarkers

8 July 2018

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A phase 1 study of everolimus plus docetaxel plus cisplatin as induction chemotherapy for patients with locally and/or regionally advanced head and neck cancer

8 July 2018

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A phase II study of temsirolimus and erlotinib in patients with recurrent and/or metastatic, platinum-refractory head and neck squamous cell carcinoma

8 July 2018

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The p53-reactivating small-molecule RITA enhances cisplatin-induced cytotoxicity and apoptosis in head and neck cancer

8 July 2018

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Phase I study of RO4929097, a gamma secretase inhibitor of Notch signaling, in patients with refractory metastatic or locally advanced solid tumors

8 July 2018

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TP53 disruptive mutations lead to head and neck cancer treatment failure through inhibition of radiation-induced senescence.

8 July 2018

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Loss-of-function mutations in Notch receptors in cutaneous and lung squamous cell carcinoma

8 July 2018

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Phase I trial of ALT-801, an interleukin-2/T-cell receptor fusion protein targeting p53 (aa264-272)/HLA-A*0201 complex, in patients with advanced malignancies

8 July 2018

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Human Papillomavirus and Rising Oropharyngeal Cancer Incidence in the United States

8 July 2018

1 reference

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Exome sequencing of head and neck squamous cell carcinoma reveals inactivating mutations in NOTCH1

8 July 2018

1 reference

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The mutational landscape of head and neck squamous cell carcinoma

8 July 2018

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Whole-genome sequencing identifies recurrent mutations in chronic lymphocytic leukaemia

8 July 2018

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8 July 2018

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Tumor-derived JAGGED1 promotes osteolytic bone metastasis of breast cancer by engaging notch signaling in bone cells

8 July 2018

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The molecular biology of head and neck cancer

8 July 2018

1 reference

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The PI3K pathway as drug target in human cancer

8 July 2018

1 reference

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TP53 mutations and pathologic complete response to neoadjuvant cisplatin and fluorouracil chemotherapy in resected oral cavity squamous cell carcinoma.

8 July 2018

1 reference

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Functional p53 status as a biomarker for chemotherapy response in oral-cavity cancer

8 July 2018

1 reference

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Microdroplet-based PCR enrichment for large-scale targeted sequencing

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4329919

A phase 2 trial of surgery with perioperative INGN 201 (Ad5CMV-p53) gene therapy followed by chemoradiotherapy for advanced, resectable squamous cell carcinoma of the oral cavity, oropharynx, hypopharynx, and larynx: report of the Southwest Oncology

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4329919

Human papillomavirus and head and neck squamous cell carcinoma: recent evidence and clinical implications

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4329919

TP53 mutations and survival in squamous-cell carcinoma of the head and neck.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4329919

Impaired notch signaling promotes de novo squamous cell carcinoma formation

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4329919

Activating mutations of NOTCH1 in human T cell acute lymphoblastic leukemia

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4329919

Notch1 functions as a tumor suppressor in mouse skin

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4329919

Genetic events in head and neck squamous cell carcinoma revealed.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4329919

High frequency of activating PIK3CA mutations in human papillomavirus-positive oropharyngeal cancer

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4329919

Cancer. Another NOTCH for cancer.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4329919

p53 alterations predict tumor response to neoadjuvant chemotherapy in head and neck squamous cell carcinoma: a prospective series.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4329919

Recent advances in head and neck cancer

27 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25440877

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Phase I pharmacologic and pharmacodynamic study of the gamma secretase (Notch) inhibitor MK-0752 in adult patients with advanced solid tumors

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25440877

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1111/NYAS.12599

1 reference

6 August 2017

1 reference

6 August 2017

1 reference