Amyloid beta-protein interactions with membranes and cholesterol: causes or casualties of Alzheimer's disease (Q35089446)

6 August 2017

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title

Amyloid beta-protein interactions with membranes and cholesterol: causes or casualties of Alzheimer's disease (English)

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6 August 2017

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W Gibson Wood

1

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6 August 2017

Gunter P Eckert

series ordinal

2

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6 August 2017

Urule Igbavboa

series ordinal

3

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6 August 2017

Walter E Müller

series ordinal

4

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6 August 2017

language of work or name

English

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publication date

1 March 2003

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Biochimica et Biophysica Acta

6 August 2017

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6 August 2017

1610

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6 August 2017

2

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6 August 2017

281-290

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Cell biology of the amyloid beta-protein precursor and the mechanism of Alzheimer's disease

6 August 2017

1 reference

https://api.crossref.org/works/10.1016%2FS0005-2736%2803%2900025-7

Alzheimer's disease: genes, proteins, and therapy

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0005-2736%2803%2900025-7

Neurotrophic and neurotoxic effects of amyloid beta protein: reversal by tachykinin neuropeptides

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0005-2736%2803%2900025-7

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0005-2736%2803%2900025-7

Alzheimer disease amyloid beta protein forms calcium channels in bilayer membranes: blockade by tromethamine and aluminum

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0005-2736%2803%2900025-7

The toxicity in vitro of beta-amyloid protein

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0005-2736%2803%2900025-7

Understanding the biological activity of amyloid proteins in vitro: from inhibited cellular MTT reduction to altered cellular cholesterol homeostatis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0005-2736%2803%2900025-7

Cortical senile plaques in coronary artery disease, aging and Alzheimer's disease

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0005-2736%2803%2900025-7

Induction of Alzheimer-like beta-amyloid immunoreactivity in the brains of rabbits with dietary cholesterol.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0005-2736%2803%2900025-7

Association of apolipoprotein E allele epsilon 4 with late-onset familial and sporadic Alzheimer's disease

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0005-2736%2803%2900025-7

Decreased prevalence of Alzheimer disease associated with 3-hydroxy-3-methyglutaryl coenzyme A reductase inhibitors.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0005-2736%2803%2900025-7

Statins and the risk of dementia

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0005-2736%2803%2900025-7

Acceleration of amyloid fibril formation by specific binding of Abeta-(1-40) peptide to ganglioside-containing membrane vesicles

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0005-2736%2803%2900025-7

Membrane phospholipid alterations in Alzheimer's disease: deficiency of ethanolamine plasmalogens

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0005-2736%2803%2900025-7

Plasmalogen deficiency in early Alzheimer's disease subjects and in animal models: molecular characterization using electrospray ionization mass spectrometry

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0005-2736%2803%2900025-7

Interactions of amyloid beta-peptide (1-40) with ganglioside-containing membranes

7 January 2021

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https://api.crossref.org/works/10.1016%2FS0005-2736%2803%2900025-7

Characterization of the interactions of Alzheimer beta-amyloid peptides with phospholipid membranes.

7 January 2021

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https://api.crossref.org/works/10.1016%2FS0005-2736%2803%2900025-7

Regional membrane phospholipid alterations in Alzheimer's disease.

7 January 2021

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https://api.crossref.org/works/10.1016%2FS0005-2736%2803%2900025-7

GM1 ganglioside-bound amyloid beta-protein (A beta): a possible form of preamyloid in Alzheimer's disease.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0005-2736%2803%2900025-7

Annexin 5 and apolipoprotein E2 protect against Alzheimer's amyloid-beta-peptide cytotoxicity by competitive inhibition at a common phosphatidylserine interaction site

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0005-2736%2803%2900025-7

Amyloid beta protein (Abeta) starts to deposit as plasma membrane-bound form in diffuse plaques of brains from hereditary cerebral hemorrhage with amyloidosis-Dutch type, Alzheimer disease and nondemented aged subjects

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0005-2736%2803%2900025-7

Ultrastructural evidence of fibrillar beta-amyloid associated with neuronal membranes in behaviorally characterized aged dog brains.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0005-2736%2803%2900025-7

Accumulation of amyloid beta-protein in the low-density membrane domain accurately reflects the extent of beta-amyloid deposition in the brain

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0005-2736%2803%2900025-7

Amyloid precursor protein in unique cholesterol-rich microdomains different from caveolae-like domains

7 January 2021

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https://api.crossref.org/works/10.1016%2FS0005-2736%2803%2900025-7

Cholesterol-dependent localization of NAP-22 on a neuronal membrane microdomain (raft).

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0005-2736%2803%2900025-7

The Presence of Amyloid β-Protein in the Detergent-Insoluble Membrane Compartment of Human Neuroblastoma Cells†

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0005-2736%2803%2900025-7

Interaction of Alzheimer beta-amyloid peptide(1-40) with lipid membranes

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0005-2736%2803%2900025-7

Alzheimer's disease amyloid beta peptide 25-35 is localized in the membrane hydrocarbon core: x-ray diffraction analysis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0005-2736%2803%2900025-7

Distribution and fluidizing action of soluble and aggregated amyloid beta-peptide in rat synaptic plasma membranes.

7 January 2021

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https://api.crossref.org/works/10.1016%2FS0005-2736%2803%2900025-7

Charged anesthetics selectively alter plasma membrane order

7 January 2021

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https://api.crossref.org/works/10.1016%2FS0005-2736%2803%2900025-7

Charged anaesthetics alter LM-fibroblast plasma-membrane enzymes by selective fluidization of inner or outer membrane leaflets

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0005-2736%2803%2900025-7

Membrane disruption by Alzheimer beta-amyloid peptides mediated through specific binding to either phospholipids or gangliosides. Implications for neurotoxicity.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0005-2736%2803%2900025-7

Apolipoprotein E and cholesterol affect neuronal calcium signalling: the possible relationship to beta-amyloid neurotoxicity

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0005-2736%2803%2900025-7

beta-Amyloid peptide decreases membrane fluidity.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0005-2736%2803%2900025-7

Effects of beta-amyloid peptides on the fluidity of membranes from frontal and parietal lobes of human brain. High potencies of A beta 1-42 and A beta 1-43.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0005-2736%2803%2900025-7

Cholesterol modulates the membrane-disordering effects of beta-amyloid peptides in the hippocampus: specific changes in Alzheimer's disease.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0005-2736%2803%2900025-7

Effects of aging and beta-amyloid on the properties of brain synaptic and mitochondrial membranes

7 January 2021

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https://api.crossref.org/works/10.1016%2FS0005-2736%2803%2900025-7

Correlation of beta-amyloid aggregate size and hydrophobicity with decreased bilayer fluidity of model membranes

7 January 2021

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https://api.crossref.org/works/10.1016%2FS0005-2736%2803%2900025-7

Cellular membrane composition defines A beta-lipid interactions

7 January 2021

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https://api.crossref.org/works/10.1016%2FS0005-2736%2803%2900025-7

Cholesterol, a modulator of membrane-associated Abeta-fibrillogenesis and neurotoxicity.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0005-2736%2803%2900025-7

Nuclear magnetic resonance studies of lecithin bimolecular leaflets with incorporated fluorescent probes

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0005-2736%2803%2900025-7

Lipid fluidity of the individual hemileaflets of human erythrocyte membranes

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0005-2736%2803%2900025-7

Transbilayer effects of ethanol on fluidity of brain membrane leaflets.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0005-2736%2803%2900025-7

Curvature properties of novel forms of phosphatidylcholine with branched acyl chains

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0005-2736%2803%2900025-7

Relationship of membrane curvature to the formation of pores by magainin 2

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0005-2736%2803%2900025-7

Hydrophilicity/lipophilicity: relevance for the pharmacology and clinical effects of HMG-CoA reductase inhibitors

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0005-2736%2803%2900025-7

Concentrations of pravastatin and lovastatin in cerebrospinal fluid in healthy subjects.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0005-2736%2803%2900025-7

Differential effects of lovastatin treatment on brain cholesterol levels in normal and apoE-deficient mice

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0005-2736%2803%2900025-7

Transbilayer distribution of cholesterol is modified in brain synaptic plasma membranes of knockout mice deficient in the low-density lipoprotein receptor, apolipoprotein E, or both proteins.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0005-2736%2803%2900025-7

Modulation of COX-2 expression by statins in human aortic smooth muscle cells. Involvement of geranylgeranylated proteins

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0005-2736%2803%2900025-7

Effects of the 3-hydroxy-3-methylglutaryl-CoA reductase inhibitors, atorvastatin and simvastatin, on the expression of endothelin-1 and endothelial nitric oxide synthase in vascular endothelial cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0005-2736%2803%2900025-7

Lovastatin induces apoptosis in malignant mesothelioma cells.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0005-2736%2803%2900025-7

Statins inhibit A beta-neurotoxicity in vitro and A beta-induced vasoconstriction and inflammation in rat aortae

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0005-2736%2803%2900025-7

The inflammatory response system of brain: implications for therapy of Alzheimer and other neurodegenerative diseases

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0005-2736%2803%2900025-7

Coronary artery disease, hypertension, ApoE, and cholesterol: a link to Alzheimer's disease?

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0005-2736%2803%2900025-7

Evidence for changes in the Alzheimer's disease brain cortical membrane structure mediated by cholesterol.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0005-2736%2803%2900025-7

3-hydroxy-3-methylglutaryl-coenzyme A reductase mRNA in Alzheimer and control brain

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0005-2736%2803%2900025-7

24S-hydroxycholesterol in cerebrospinal fluid is elevated in early stages of dementia

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0005-2736%2803%2900025-7

Cholesterol homeostasis in human brain: evidence for an age-dependent flux of 24S-hydroxycholesterol from the brain into the circulation

7 January 2021

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https://api.crossref.org/works/10.1016%2FS0005-2736%2803%2900025-7

Cholesterol in the year 2000.

7 January 2021

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https://api.crossref.org/works/10.1016%2FS0005-2736%2803%2900025-7

Recent advances in brain cholesterol dynamics: transport, domains, and Alzheimer's disease

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0005-2736%2803%2900025-7

Brain membrane cholesterol domains, aging and amyloid beta-peptides

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0005-2736%2803%2900025-7

Hypercholesterolemia accelerates the Alzheimer's amyloid pathology in a transgenic mouse model

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0005-2736%2803%2900025-7

Modulation of secreted beta-amyloid precursor protein and amyloid beta-peptide in brain by cholesterol.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0005-2736%2803%2900025-7

Simvastatin strongly reduces levels of Alzheimer's disease beta -amyloid peptides Abeta 42 and Abeta 40 in vitro and in vivo

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0005-2736%2803%2900025-7

Rates of cholesterol, ubiquinone, dolichol and dolichyl-P biosynthesis in rat brain slices

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0005-2736%2803%2900025-7

Low-density lipoprotein receptor on endothelium of brain capillaries

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0005-2736%2803%2900025-7

A new function for the LDL receptor: transcytosis of LDL across the blood-brain barrier

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0005-2736%2803%2900025-7

Profile of cholesterol-related sterols in aged amyloid precursor protein transgenic mouse brain

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0005-2736%2803%2900025-7

Cholesterol modulates alpha-secretase cleavage of amyloid precursor protein

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0005-2736%2803%2900025-7

Low cholesterol stimulates the nonamyloidogenic pathway by its effect on the alpha -secretase ADAM 10.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0005-2736%2803%2900025-7

Cholesterol depletion inhibits the generation of beta-amyloid in hippocampal neurons

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0005-2736%2803%2900025-7

Axonal amyloid precursor protein expressed by neurons in vitro is present in a membrane fraction with caveolae-like properties.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0005-2736%2803%2900025-7

A detergent-insoluble membrane compartment contains A beta in vivo.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0005-2736%2803%2900025-7

Inhibition of intracellular cholesterol transport alters presenilin localization and amyloid precursor protein processing in neuronal cells.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0005-2736%2803%2900025-7

Cholesterol as modulator of receptor function.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0005-2736%2803%2900025-7

Cholesterol oxidation reduces Ca(2+)+MG (2+)-ATPase activity, interdigitation, and increases fluidity of brain synaptic plasma membranes

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0005-2736%2803%2900025-7

Increased membrane cholesterol reduces the potentiation of GABA(A) currents by neurosteroids in dissociated hippocampal neurones.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0005-2736%2803%2900025-7

Influence of membrane cholesterol on modulation of the GABA(A) receptor by neuroactive steroids and other potentiators

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0005-2736%2803%2900025-7

Effects of membrane cholesterol on the sensitivity of the GABA(A) receptor to GABA in acutely dissociated rat hippocampal neurones

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0005-2736%2803%2900025-7

Cholesterol protects PC12 cells from beta-amyloid induced calcium disordering and cytotoxicity.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0005-2736%2803%2900025-7

Multiple inhibitory effects of Alzheimer's peptide Abeta1-40 on lipid biosynthesis in cultured human HepG2 cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0005-2736%2803%2900025-7

Amyloid beta peptide alters intracellular vesicle trafficking and cholesterol homeostasis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0005-2736%2803%2900025-7

Apolipoprotein E and low-density lipoprotein binding and internalization in primary cultures of rat astrocytes: isoform-specific alterations

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0005-2736%2803%2900025-7

A novel action of alzheimer's amyloid beta-protein (Abeta): oligomeric Abeta promotes lipid release.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0005-2736%2803%2900025-7

Lipid binding to amyloid beta-peptide aggregates: preferential binding of cholesterol as compared with phosphatidylcholine and fatty acids

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0005-2736%2803%2900025-7

Transport of lipids from golgi to plasma membrane is defective in tangier disease patients and Abc1-deficient mice.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0005-2736%2803%2900025-7

Cholesterol is increased in the exofacial leaflet of synaptic plasma membranes of human apolipoprotein E4 knock-in mice

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0005-2736%2803%2900025-7

Asymmetric distribution of a fluorescent sterol in synaptic plasma membranes: effects of chronic ethanol consumption

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0005-2736%2803%2900025-7

How cells handle cholesterol.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0005-2736%2803%2900025-7

Cholesterol-dependent generation of a unique amyloid beta-protein from apically missorted amyloid precursor protein in MDCK cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0005-2736%2803%2900025-7

Cholesterol-dependent Generation of a Seeding Amyloid β-Protein in Cell Culture

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0005-2736%2803%2900025-7

Fluorescence probes unravel asymmetric structure of membranes.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0005-2736%2803%2900025-7

7 January 2021

Recent advances in membrane microdomains: rafts, caveolae, and intracellular cholesterol trafficking

1 reference

https://api.crossref.org/works/10.1016%2FS0005-2736%2803%2900025-7

7 January 2021

Monensin and brefeldin A inhibit high density lipoprotein-mediated cholesterol efflux from cholesterol-enriched cells. Implications for intracellular cholesterol transport

1 reference

https://api.crossref.org/works/10.1016%2FS0005-2736%2803%2900025-7

7 January 2021

Principles of Fluorescence Spectroscopy

1 reference

https://api.crossref.org/works/10.1016%2FS0005-2736%2803%2900025-7

7 January 2021

10.1016/S0005-2736(03)00025-7

Identifiers

DOI

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6 August 2017

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