Lysophosphatidylcholines activate G2A inducing G(αi)₋₁-/G(αq/)₁₁- Ca²(+) flux, G(βγ)-Hck activation and clathrin/β-arrestin-1/GRK6 recruitment in PMNs. (Q35090466)

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English	Lysophosphatidylcholines activate G2A inducing G(αi)₋₁-/G(αq/)₁₁- Ca²(+) flux, G(βγ)-Hck activation and clathrin/β-arrestin-1/GRK6 recruitment in PMNs.	scientific article

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13 February 2020

Lysophosphatidylcholines activate G2A inducing G(αi)₋₁-/G(αq/)₁₁- Ca²(+) flux, G(βγ)-Hck activation and clathrin/β-arrestin-1/GRK6 recruitment in PMNs (English)

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13 February 2020

Anirban Banerjee

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13 February 2020

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Samina Y Khan

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13 February 2020

Nathan J D McLaughlin

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13 February 2020

Marguerite R Kelher

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13 February 2020

Phillip Eckels

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13 February 2020

Fabia Gamboni-Robertson

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13 February 2020

Christopher C Silliman

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13 February 2020

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1 November 2010

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13 February 2020

Biochemical Journal

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13 February 2020

432

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13 February 2020

1

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13 February 2020

35-45

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13 February 2020

Platelet-activating factor-mediated endosome formation causes membrane translocation of p67phox and p40phox that requires recruitment and activation of p38 MAPK, Rab5a, and phosphatidylinositol 3-kinase in human neutrophils.

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8 July 2018

Lysophospholipids of different classes mobilize neutrophil secretory vesicles and induce redundant signaling through G2A

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8 July 2018

The Src family kinases Hck and Fgr regulate neutrophil responses to N-formyl-methionyl-leucyl-phenylalanine

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8 July 2018

G protein-coupled receptor kinase and beta-arrestin-mediated desensitization of the angiotensin II type 1A receptor elucidated by diacylglycerol dynamics.

1 reference

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8 July 2018

GRKs and arrestins: regulators of migration and inflammation

1 reference

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8 July 2018

Clathrin required for phosphorylation and internalization of beta2-adrenergic receptor by G protein-coupled receptor kinase 2 (GRK2).

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8 July 2018

G-protein-coupled receptor kinase specificity for beta-arrestin recruitment to the beta2-adrenergic receptor revealed by fluorescence resonance energy transfer

1 reference

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8 July 2018

Unbound free fatty acids and heart-type fatty acid-binding protein: diagnostic assays and clinical applications

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8 July 2018

Transduction of receptor signals by beta-arrestins

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8 July 2018

beta-arrestins: traffic cops of cell signaling

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8 July 2018

G protein signaling: insights from new structures.

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8 July 2018

Therapeutic effects of lysophosphatidylcholine in experimental sepsis

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8 July 2018

T cell chemotaxis to lysophosphatidylcholine through the G2A receptor.

1 reference

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8 July 2018

Regulated portals of entry into the cell

1 reference

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8 July 2018

Diacylglycerol and ceramide formation induced by dopamine D2S receptors via Gbeta gamma -subunits in Balb/c-3T3 cells

1 reference

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8 July 2018

The role of beta-arrestins in the termination and transduction of G-protein-coupled receptor signals

1 reference

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8 July 2018

Regulation of tyrosine kinase activation and granule release through beta-arrestin by CXCRI

1 reference

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8 July 2018

Regulation of tyrosine kinase cascades by G-protein-coupled receptors.

1 reference

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8 July 2018

Differential regulation of mitogen-activated protein kinase kinase 4 (MKK4) and 7 (MKK7) by signaling from G protein beta gamma subunit in human embryonal kidney 293 cells

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Plasma and lipids from stored packed red blood cells cause acute lung injury in an animal model.

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8 July 2018

Dopamine receptors: from structure to function

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8 July 2018

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27 September 2018

Identification of a phospholipase C beta2 region that interacts with Gbeta-gamma

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8 July 2018

Adhesion molecules and inflammatory injury.

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8 July 2018

FMLP activates Ras and Raf in human neutrophils. Potential role in activation of MAP kinase

1 reference

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8 July 2018

Partial characterization of lipids that develop during the routine storage of blood and prime the neutrophil NADPH oxidase.

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8 July 2018

Chemoattractant signaling and leukocyte activation

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8 July 2018

Regulation of human leukocyte p21-activated kinases through G protein--coupled receptors

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8 July 2018

Leukocyte-endothelial adhesion molecules

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8 July 2018

Lysophosphatidylcholine: a chemotactic factor for human monocytes and its potential role in atherogenesis

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8 July 2018

Electrophysiologic effects of intracellular lysophosphoglycerides and their accumulation in cardiac lymph with myocardial ischemia in dogs

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8 July 2018

Subunits beta gamma of heterotrimeric G protein activate beta 2 isoform of phospholipase C

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8 July 2018

Oscillations of cytosolic free calcium concentration in the presence of intracellular antibodies to phosphatidylinositol 4,5-bisphosphate in voltage-clamped guinea-pig hepatocytes

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8 July 2018

Occupancy of G alpha s-linked receptors uncouples chemoattractant receptors from their stimulus-transduction mechanisms in the neutrophil

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8 July 2018

Impaired neutrophil chemotaxis in sepsis associates with GRK expression and inhibition of actin assembly and tyrosine phosphorylation.

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21 January 2018

Increased acute inflammation, leukotriene B4-induced chemotaxis, and signaling in mice deficient for G protein-coupled receptor kinase 6.

1 reference

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21 January 2018

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21 January 2018

Cell signaling. Beta-arrestin, a two-fisted terminator

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21 January 2018

Lysophosphatidylcholines prime the NADPH oxidase and stimulate multiple neutrophil functions through changes in cytosolic calcium

1 reference

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Suppression of HMGB1 release by stearoyl lysophosphatidylcholine:an additional mechanism for its therapeutic effects in experimental sepsis

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Lysophosphatidylcholine modulates neutrophil oxidant production through elevation of cyclic AMP.

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27 September 2018

Intracellular Signaling Pathway of Endothelin-1

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12 December 2020

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The presence of free G protein beta/gamma subunits in human neutrophils results in suppression of adenylate cyclase activity

1 reference

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based on heuristic

inferred from PubMed ID database lookup

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1 reference

https://pubmed.ncbi.nlm.nih.gov/20799926

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Signal transduction by the formyl peptide receptor. Studies using chimeric receptors and site-directed mutagenesis define a novel domain for interaction with G-proteins

1 reference

https://pubmed.ncbi.nlm.nih.gov/20799926

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based on heuristic

inferred from PubMed ID database lookup

Platelet-activating factor-induced clathrin-mediated endocytosis requires beta-arrestin-1 recruitment and activation of the p38 MAPK signalosome at the plasma membrane for actin bundle formation

1 reference

https://pubmed.ncbi.nlm.nih.gov/20799926

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based on heuristic

inferred from PubMed ID database lookup

The Src family kinases Hck and Fgr are dispensable for inside-out, chemoattractant-induced signaling regulating beta 2 integrin affinity and valency in neutrophils, but are required for beta 2 integrin-mediated outside-in signaling involved in susta

1 reference

https://pubmed.ncbi.nlm.nih.gov/20799926

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Lysophosphatidylcholine and lyso-PAF display PAF-like activity derived from contaminating phospholipids

1 reference

https://pubmed.ncbi.nlm.nih.gov/20799926

12 December 2020

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A two-insult in vitro model of PMN-mediated pulmonary endothelial damage: requirements for adherence and chemokine release

1 reference

https://pubmed.ncbi.nlm.nih.gov/20799926

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inferred from PubMed ID database lookup

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https://pubmed.ncbi.nlm.nih.gov/20799926

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inferred from PubMed ID database lookup

Identifiers

10.1042/BJ20091087

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20799926%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

PMC publication ID

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Europe PubMed Central

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13 February 2020

PubMed publication ID

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20799926%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

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