Therapeutic challenges to retinitis pigmentosa: from neuroprotection to gene therapy. (Q35092187)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22131873%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

title

Therapeutic challenges to retinitis pigmentosa: from neuroprotection to gene therapy (English)

1 reference

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17 January 2020

0 references

1 reference

2

1 reference

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17 January 2020

Cristina Irigoyen

3

1 reference

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17 January 2020

Francesco Semeraro

4

1 reference

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17 January 2020

author name string

Jayashree N Sahni

1

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17 January 2020

Mario R Romano

5

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17 January 2020

Francesco Parmeggiani

6

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17 January 2020

publication date

1 June 2011

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17 January 2020

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17 January 2020

volume

12

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17 January 2020

issue

4

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17 January 2020

page(s)

276-284

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Gene therapy for vision loss -- recent developments

17 January 2020

cites work

1 reference

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Current concepts in the treatment of retinitis pigmentosa

8 July 2018

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Treatment possibilities for retinitis pigmentosa

8 July 2018

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Blind subjects implanted with the Argus II retinal prosthesis are able to improve performance in a spatial-motor task

8 July 2018

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Efficacy of sustained topical dorzolamide therapy for cystic macular lesions in patients with retinitis pigmentosa and usher syndrome

8 July 2018

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Looking ahead: planning for the first human intracortical visual prosthesis by using pilot data from focus groups of potential users

8 July 2018

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The ATP-binding cassette transporter ABCA4: structural and functional properties and role in retinal disease

8 July 2018

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Genetic reactivation of cone photoreceptors restores visual responses in retinitis pigmentosa

8 July 2018

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Leber congenital amaurosis due to RPE65 mutations and its treatment with gene therapy

8 July 2018

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Clinical trial of lutein in patients with retinitis pigmentosa receiving vitamin A

8 July 2018

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Gene therapy for Leber's congenital amaurosis is safe and effective through 1.5 years after vector administration

8 July 2018

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Induced pluripotent stem cell therapies for retinal disease

8 July 2018

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Age-dependent effects of RPE65 gene therapy for Leber's congenital amaurosis: a phase 1 dose-escalation trial

8 July 2018

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Animal models and different therapies for treatment of retinitis pigmentosa.

8 July 2018

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Artificial vision: needs, functioning, and testing of a retinal electronic prosthesis

8 July 2018

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Cell transplantation strategies for retinal repair.

8 July 2018

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Human RPE65 gene therapy for Leber congenital amaurosis: persistence of early visual improvements and safety at 1 year

8 July 2018

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Review and update: current treatment trends for patients with retinitis pigmentosa

8 July 2018

1 reference

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Generation of retinal cells from mouse and human induced pluripotent stem cells

8 July 2018

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Functional cone rescue by RdCVF protein in a dominant model of retinitis pigmentosa

8 July 2018

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Photoreceptor cell death mechanisms in inherited retinal degeneration.

8 July 2018

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NT-501: an ophthalmic implant of polymer-encapsulated ciliary neurotrophic factor-producing cells.

8 July 2018

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Treatment of leber congenital amaurosis due to RPE65 mutations by ocular subretinal injection of adeno-associated virus gene vector: short-term results of a phase I trial

8 July 2018

1 reference

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Effect of gene therapy on visual function in Leber's congenital amaurosis

8 July 2018

1 reference

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Safety and efficacy of gene transfer for Leber's congenital amaurosis

8 July 2018

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Novel AAV serotypes for improved ocular gene transfer

8 July 2018

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Reversal of blindness in animal models of leber congenital amaurosis using optimized AAV2-mediated gene transfer

8 July 2018

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Chronic intravitreous infusion of ciliary neurotrophic factor modulates electrical retinal stimulation thresholds in the RCS rat.

8 July 2018

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RPE transplantation and its role in retinal disease

8 July 2018

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Stem cell therapy and the retina

8 July 2018

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RNA interference-mediated suppression and replacement of human rhodopsin in vivo

8 July 2018

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Preventing blindness in retinal disease: ciliary neurotrophic factor intraocular implants

8 July 2018

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Hot spots of retroviral integration in human CD34+ hematopoietic cells

8 July 2018

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XIAP protection of photoreceptors in animal models of retinitis pigmentosa

8 July 2018

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Visual acuity and perimacular retinal layers detected by optical coherence tomography in patients with retinitis pigmentosa

8 July 2018

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8 July 2018

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8 July 2018

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Diseases caused by defects in the visual cycle: retinoids as potential therapeutic agents

8 July 2018

1 reference

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Safety in nonhuman primates of ocular AAV2-RPE65, a candidate treatment for blindness in Leber congenital amaurosis

8 July 2018

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G protein-coupled receptor rhodopsin

8 July 2018

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Light and inherited retinal degeneration

8 July 2018

1 reference

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Cell survival matters: docosahexaenoic acid signaling, neuroprotection and photoreceptors

8 July 2018

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Ciliary neurotrophic factor (CNTF) for human retinal degeneration: phase I trial of CNTF delivered by encapsulated cell intraocular implants

8 July 2018

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The consortium project to treat RPE65 deficiency in humans

8 July 2018

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Long-term results of submacular surgery combined with macular translocation of the retinal pigment epithelium in neovascular age-related macular degeneration.

8 July 2018

1 reference

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Long-term restoration of rod and cone vision by single dose rAAV-mediated gene transfer to the retina in a canine model of childhood blindness

8 July 2018

1 reference

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The retinal pigment epithelium in visual function

8 July 2018

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Molecular mechanisms of light-induced photoreceptor apoptosis and neuroprotection for retinal degeneration

8 July 2018

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Ciliary neurotrophic factor (CNTF) for amyotrophic lateral sclerosis or motor neuron disease

8 July 2018

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Identification and characterization of rod-derived cone viability factor

8 July 2018

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Channelrhodopsin-2, a directly light-gated cation-selective membrane channel

8 July 2018

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The gene for Stargardt disease, ABCA4, is a major retinal gene: a mini-review

8 July 2018

1 reference

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Recombinant adeno-associated virus serotype 4 mediates unique and exclusive long-term transduction of retinal pigmented epithelium in rat, dog, and nonhuman primate after subretinal delivery

8 July 2018

1 reference

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Randomized, double-blind trial of glial cell line-derived neurotrophic factor (GDNF) in PD.

8 July 2018

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Gene therapy with viral vectors

8 July 2018

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Encapsulated cell-based delivery of CNTF reduces photoreceptor degeneration in animal models of retinitis pigmentosa.

8 July 2018

1 reference

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Recovery of visual functions in a mouse model of Leber congenital amaurosis

8 July 2018

1 reference

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Outcome of cataract surgery in patients with retinitis pigmentosa

8 July 2018

1 reference

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The role of carbonic anhydrase inhibitors in the management of macular edema

8 July 2018

1 reference

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Rapid restoration of visual pigment and function with oral retinoid in a mouse model of childhood blindness

8 July 2018

1 reference

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Retinal stem cells in the adult mammalian eye

8 July 2018

1 reference

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The implications of rod-dependent cone survival for basic and clinical research.

8 July 2018

1 reference

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Retinal dystrophy of Swedish briard/briard-beagle dogs is due to a 4-bp deletion in RPE65.

8 July 2018

1 reference

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Intravitreous transplantation of encapsulated fibroblasts secreting the human fibroblast growth factor 2 delays photoreceptor cell degeneration in Royal College of Surgeons rats

8 July 2018

1 reference

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Retinitis pigmentosa: defined from a molecular point of view

8 July 2018

1 reference

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Congenital stationary night blindness in the dog: common mutation in the RPE65 gene indicates founder effect.

8 July 2018

1 reference

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Normal retina releases a diffusible factor stimulating cone survival in the retinal degeneration mouse

8 July 2018

1 reference

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Disease sequence from mutant rhodopsin allele to rod and cone photoreceptor degeneration in man.

8 July 2018

1 reference

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The 220-kDa rim protein of retinal rod outer segments is a member of the ABC transporter superfamily

8 July 2018

1 reference

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A randomized trial of vitamin A and vitamin E supplementation for retinitis pigmentosa

8 July 2018

1 reference

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Nutrition and retinal degenerations. Vitamin A, taurine, ornithine, and phytanic acid

8 July 2018

1 reference

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Molecular cloning, primary structure, and orientation of the vertebrate photoreceptor cell protein peripherin in the rod outer segment disk membrane

8 July 2018

1 reference

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Human photoreceptor topography

8 July 2018

1 reference

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Survival and Synapse Formation of Transplanted Rat Rods

8 July 2018

1 reference

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Cloning of the CDNA for a novel photoreceptor membrane protein (rom-1) identifies a disk rim protein family implicated in human retinopathies

8 July 2018

1 reference

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Subretinal electronic chips allow blind patients to read letters and combine them to words.

8 July 2018

1 reference

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Photoreceptor rescue and toxicity induced by different calpain inhibitors.

27 September 2018

1 reference

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Vision improvement in retinal degeneration patients by implantation of retina together with retinal pigment epithelium

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3131735

In vivo stimulation on rabbit retina using CMOS LSI-based multi-chip flexible stimulator for retinal prosthesis

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3131735

A transgenic mouse model for gene therapy of rhodopsin-linked Retinitis Pigmentosa

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3131735

Experimental implantation of epiretinal retina implants (EPI-RET) with an IOL-type receiver unit.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3131735

Development of an epiretinal prosthesis for stimulation of the human retina

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3131735

Multipotent retinal progenitors express developmental markers, differentiate into retinal neurons, and preserve light-mediated behavior

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3131735

Further evaluation of docosahexaenoic acid in patients with retinitis pigmentosa receiving vitamin A treatment: subgroup analyses

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3131735

Perceptual efficacy of electrical stimulation of human retina with a microelectrode array during short-term surgical trials

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3131735

Neuronal Integration in an Abutting-Retinas Culture System

27 September 2018

1 reference

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11-cis-retinal reduces constitutive opsin phosphorylation and improves quantum catch in retinoid-deficient mouse rod photoreceptors

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3131735

Gene therapy restores vision in a canine model of childhood blindness

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3131735

Ribozyme rescue of photoreceptor cells in a transgenic rat model of autosomal dominant retinitis pigmentosa.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3131735

Transplantation of embryonic retina to adult retina in rabbits

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3131735

Implantable hearing devices

27 September 2018

1 reference

12 December 2020

How strong is the evidence that nutritional supplements slow the progression of retinitis pigmentosa?

1 reference

12 December 2020

Psychosocial adjustment to visual loss in patients with retinitis pigmentosa

1 reference

12 December 2020

Long-term photoreceptor transplants in dystrophic and normal mouse retina

1 reference

12 December 2020

Protection against photic damage in retinitis pigmentosa

1 reference

12 December 2020

Photoreceptor degeneration in inherited retinal dystrophy delayed by basic fibroblast growth factor

1 reference

12 December 2020

Preservation of the Inner Retina in Retinitis Pigmentosa

1 reference

12 December 2020

10.2174/138920211795860062

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22131873%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22131873%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

1 reference