Genome-wide saturation mutagenesis of Burkholderia pseudomallei K96243 predicts essential genes and novel targets for antimicrobial development (Q35092525)

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English	Genome-wide saturation mutagenesis of Burkholderia pseudomallei K96243 predicts essential genes and novel targets for antimicrobial development	scientific article

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scholarly article

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Europe PubMed Central

6 August 2017

Genome-wide saturation mutagenesis of Burkholderia pseudomallei K96243 predicts essential genes and novel targets for antimicrobial development (English)

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Europe PubMed Central

6 August 2017

Burkholderia pseudomallei

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Claudia M Hemsley

2

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5 June 2020

José Afonso Guerra-assunção

4

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5 June 2020

7

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5 June 2020

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Madeleine G Moule

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5 June 2020

Qihui Seet

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5 June 2020

Jiali Lim

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5 June 2020

Mitali Sarkar-Tyson

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5 June 2020

Patrick B O Tan

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5 June 2020

Jon Cuccui

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5 June 2020

Richard W Titball

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5 June 2020

Brendan W Wren

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5 June 2020

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11 February 2014

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6 August 2017

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5 June 2020

5

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5 June 2020

1

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5 June 2020

e00926-13

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5 June 2020

Combining functional and structural genomics to sample the essential Burkholderia structome

1 reference

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8 July 2018

Identification of T6SS-dependent effector and immunity proteins by Tn-seq in Vibrio cholerae

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8 July 2018

Fast gapped-read alignment with Bowtie 2

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8 July 2018

Retrospective application of transposon-directed insertion site sequencing to a library of signature-tagged mini-Tn5Km2 mutants of Escherichia coli O157:H7 screened in cattle.

1 reference

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8 July 2018

Genome-scale identification of resistance functions in Pseudomonas aeruginosa using Tn-seq

1 reference

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8 July 2018

Genome-wide fitness and genetic interactions determined by Tn-seq, a high-throughput massively parallel sequencing method for microorganisms

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8 July 2018

A genomic survey of positive selection in Burkholderia pseudomallei provides insights into the evolution of accidental virulence

1 reference

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8 July 2018

Simultaneous assay of every Salmonella Typhi gene using one million transposon mutants

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8 July 2018

Tn-seq: high-throughput parallel sequencing for fitness and genetic interaction studies in microorganisms

1 reference

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8 July 2018

DEG 5.0, a database of essential genes in both prokaryotes and eukaryotes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3950516

8 July 2018

The core and accessory genomes of Burkholderia pseudomallei: implications for human melioidosis

1 reference

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8 July 2018

Burkholderia pseudomallei genome plasticity associated with genomic island variation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3950516

8 July 2018

In vivo expression technology identifies a type VI secretion system locus in Burkholderia pseudomallei that is induced upon invasion of macrophages

1 reference

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8 July 2018

A putative gene cluster for aminoarabinose biosynthesis is essential for Burkholderia cenocepacia viability

1 reference

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8 July 2018

Development of signature-tagged mutagenesis in Burkholderia pseudomallei to identify genes important in survival and pathogenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3950516

8 July 2018

A live experimental vaccine against Burkholderia pseudomallei elicits CD4+ T cell-mediated immunity, priming T cells specific for 2 type III secretion system proteins

1 reference

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8 July 2018

Superoxide dismutase B gene (sodB)-deficient mutants of Francisella tularensis demonstrate hypersensitivity to oxidative stress and attenuated virulence

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8 July 2018

Genomic patterns of pathogen evolution revealed by comparison of Burkholderia pseudomallei, the causative agent of melioidosis, to avirulent Burkholderia thailandensis.

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3950516

8 July 2018

Construction of a mini-Tn5-luxCDABE mutant library in Pseudomonas aeruginosa PAO1: a tool for identifying differentially regulated genes

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8 July 2018

Antibiotic susceptibility of 65 isolates of Burkholderia pseudomallei and Burkholderia mallei to 35 antimicrobial agents

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8 July 2018

Genomic plasticity of the causative agent of melioidosis, Burkholderia pseudomallei

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8 July 2018

Systematic mutagenesis of the Escherichia coli genome

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8 July 2018

Application of high-density array-based signature-tagged mutagenesis to discover novel Yersinia virulence-associated genes

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8 July 2018

Expression and role of superoxide dismutases (SOD) in pathogenic bacteria

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8 July 2018

The iron superoxide dismutase of Legionella pneumophila is essential for viability

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8 July 2018

The murI gene of Escherichia coli is an essential gene that encodes a glutamate racemase activity

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8 July 2018

The evolutionary history of the first three enzymes in pyrimidine biosynthesis

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8 July 2018

Melioidosis: the tip of the iceberg?

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8 July 2018

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8 July 2018

Identification and characterization of the first class of potent bacterial acetyl-CoA carboxylase inhibitors with antibacterial activity.

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27 September 2018

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12 December 2020

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In silico analysis of Burkholderia pseudomallei genome sequence for potential drug targets

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12 December 2020

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Polysaccharides and virulence of Burkholderia pseudomallei

1 reference

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12 December 2020

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Characterisation of an acapsular mutant of Burkholderia pseudomallei identified by signature tagged mutagenesis

1 reference

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Identifiers

10.1128/MBIO.00926-13

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Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24520057%20AND%20SRC:MED&resulttype=core&format=json

5 June 2020

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5 June 2020

1 reference

Europe PubMed Central

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5 June 2020

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