Aborted germinal center reactions and B cell memory by follicular T cells specific for a B cell receptor V region peptide. (Q35097270)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21622866%20AND%20SRC:MED&resulttype=core&format=json

2 February 2020

title

Aborted germinal center reactions and B cell memory by follicular T cells specific for a B cell receptor V region peptide (English)

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2 February 2020

2

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2 February 2020

author name string

Ryan A Heiser

series ordinal

1

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2 February 2020

James St Clair

series ordinal

3

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2 February 2020

Lawrence J Wysocki

series ordinal

4

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2 February 2020

language of work or name

English

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publication date

27 May 2011

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2 February 2020

published in

Journal of Immunology

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2 February 2020

volume

187

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2 February 2020

issue

1

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2 February 2020

page(s)

212-221

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Development and migration of plasma cells in the mouse lymph node

2 February 2020

cites work

1 reference

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9 July 2018

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The function of follicular helper T cells is regulated by the strength of T cell antigen receptor binding

9 July 2018

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Cytokine-secreting follicular T cells shape the antibody repertoire

9 July 2018

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Generation of T follicular helper cells is mediated by interleukin-21 but independent of T helper 1, 2, or 17 cell lineages

9 July 2018

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Silent development of memory progenitor B cells

9 July 2018

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Naive CD4(+) T cell frequency varies for different epitopes and predicts repertoire diversity and response magnitude.

9 July 2018

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Affinity of antigen encounter and other early B-cell signals determine B-cell fate

9 July 2018

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Antigen recognition strength regulates the choice between extrafollicular plasma cell and germinal center B cell differentiation

9 July 2018

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Naive and memory CD4+ T cell survival controlled by clonal abundance

9 July 2018

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Antigen-engaged B cells undergo chemotaxis toward the T zone and form motile conjugates with helper T cells

9 July 2018

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Activation and tolerance in CD4(+) T cells reactive to an immunoglobulin variable region

9 July 2018

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T follicular helper cells express a distinctive transcriptional profile, reflecting their role as non-Th1/Th2 effector cells that provide help for B cells

9 July 2018

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Visualization of the genesis and fate of isotype-switched B cells during a primary immune response

9 July 2018

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Short-circuiting long-lived humoral immunity by the heightened engagement of CD40.

9 July 2018

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Follicular B helper T cells express CXC chemokine receptor 5, localize to B cell follicles, and support immunoglobulin production

9 July 2018

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In vivo-activated CD4 T cells upregulate CXC chemokine receptor 5 and reprogram their response to lymphoid chemokines

9 July 2018

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The J558 VH CDR3 region contributes little to antibody avidity; however, it is the recognition element for cognate T cell control of the alpha(1-->3) dextran-specific antibody response

9 July 2018

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Abortive proliferation of rare T cells induced by direct or indirect antigen presentation by rare B cells in vivo.

9 July 2018

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The extent of affinity maturation differs between the memory and antibody-forming cell compartments in the primary immune response

9 July 2018

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Induction of long-lived germinal centers associated with persisting antigen after viral infection

9 July 2018

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B cell development in mice that lack one or both immunoglobulin kappa light chain genes.

9 July 2018

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In situ studies of the primary immune response to (4-hydroxy-3-nitrophenyl)acetyl. III. The kinetics of V region mutation and selection in germinal center B cells

9 July 2018

1 reference

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Determination of lymphocyte division by flow cytometry

9 July 2018

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Soluble antigen can impede affinity maturation and the germinal center reaction but enhance extrafollicular immunoglobulin production.

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3133611

T cell determinants from autoantibodies to DNA can upregulate autoimmunity in murine systemic lupus erythematosus

9 July 2018

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Hybridoma proteins expressing the predominant idiotype of the antiazophenylarsonate response of A/J mice

9 July 2018

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Somatic evolution of variable region structures during an immune response

9 July 2018

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B-lymphoma cells process and present their endogenous immunoglobulin to major histocompatibility complex-restricted T cells

9 July 2018

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Parallel evolution of antibody variable regions by somatic processes: consecutive shared somatic alterations in VH genes expressed by independently generated hybridomas apparently acquired by point mutation and selection rather than by gene conversi

9 July 2018

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MHC class II-restricted presentation of intracellular antigen

9 July 2018

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In situ studies of the primary immune response to (4-hydroxy-3-nitrophenyl)acetyl. II. A common clonal origin for periarteriolar lymphoid sheath-associated foci and germinal centers

9 July 2018

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Multiple layers of B cell memory with different effector functions

9 July 2018

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Imaging of germinal center selection events during affinity maturation

27 September 2018

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MHC-restricted Ig V region-driven T-B lymphocyte collaboration: B cell receptor ligation facilitates switch to IgG production

27 September 2018

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A receptor presentation hypothesis for T cell help that recruits autoreactive B cells

27 September 2018

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Bcl-2 obstructs negative selection of autoreactive, hypermutated antibody V regions during memory B cell development.

27 September 2018

1 reference

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Follicular dendritic cells and presentation of antigen and costimulatory signals to B cells

27 September 2018

1 reference

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Dendritic cells associated with plasmablast survival

27 September 2018

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12 December 2020

Negligible class II MHC presentation of B cell receptor-derived peptides by high density resting B cells

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12 December 2020

T helper cell recognition of idiotopes on lambda 2 light chains of M315 and T952: evidence for dependence on somatic mutations in the third hypervariable region

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12 December 2020

Molecular events during maturation of the immune response to oxazolone

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12 December 2020

Mechanism of antigen-driven selection in germinal centres

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12 December 2020

Polyclonal activation of the murine immune system by an antibody to IgD. X. Evidence that the precursors of IgG1-secreting cells are newly generated membrane IgD+B cells rather than the B cells that are initially activated by anti-IgD antibody

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T cell recognition of somatically-generated Ab diversity

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12 December 2020

T cell recognition and tolerance of antibody diversity

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12 December 2020

Human T cell responses to autoantibody variable region peptides

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Engagement of the B lymphocyte antigen receptor induces presentation of intrinsic immunoglobulin peptides on major histocompatibility complex class II molecules

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12 December 2020

B cells alter the phenotype and function of follicular-homing CXCR5+ T cells

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12 December 2020

T cell tolerance to germline-encoded antibody sequences in a lupus-prone mouse

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Balanced expression of CXCR5 and CCR7 on follicular T helper cells determines their transient positioning to lymph node follicles and is essential for efficient B-cell help

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T cells from multiple sclerosis patients recognize multiple epitopes on Self-IgG

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Resting small B cells present endogenous immunoglobulin variable-region determinants to idiotope-specific CD4(+) T cells in vivo

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Identifiers

DOI

10.4049/JIMMUNOL.1002328

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21622866%20AND%20SRC:MED&resulttype=core&format=json

2 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21622866%20AND%20SRC:MED&resulttype=core&format=json

2 February 2020

PubMed publication ID

21622866

1 reference