Neurodegeneration: linking ubiquitin/proteasome pathway impairment with inflammation (Q35097609)

6 August 2017

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title

Neurodegeneration: linking ubiquitin/proteasome pathway impairment with inflammation (English)

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ubiquitin-proteasome system

6 August 2017

main subject

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Zongmin Li

1

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6 August 2017

Marlon Jansen

series ordinal

2

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6 August 2017

Sha-Ron Pierre

series ordinal

3

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6 August 2017

Maria E Figueiredo-Pereira

series ordinal

4

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6 August 2017

publication date

1 May 2003

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International Journal of Biochemistry & Cell Biology

6 August 2017

published in

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6 August 2017

volume

35

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6 August 2017

issue

5

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6 August 2017

page(s)

547-552

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Chaperone suppression of alpha-synuclein toxicity in a Drosophila model for Parkinson's disease

6 August 2017

cites work

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Impairment of proteasome structure and function in aging.

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Mechanisms of chaperone suppression of polyglutamine disease: selectivity, synergy and modulation of protein solubility in Drosophila.

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7 January 2021

Cyclooxygenase-2 regulates prostaglandin E2 signaling in hippocampal long-term synaptic plasticity

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Inflammatory genes are upregulated in expanded ataxin-3-expressing cell lines and spinocerebellar ataxia type 3 brains

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N-acetylcysteine and celecoxib lessen cadmium cytotoxicity which is associated with cyclooxygenase-2 up-regulation in mouse neuronal cells

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Enzymatic oxidation of dopamine: the role of prostaglandin H synthase

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The distribution and localization of hsp110 in brain

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COX-2, a synaptically induced enzyme, is expressed by excitatory neurons at postsynaptic sites in rat cerebral cortex

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7 January 2021

Cyclopentenone prostaglandins as potential inducers of intracellular oxidative stress

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Cyclooxygenase isoenzymes and newer therapeutic potential for selective COX-2 inhibitors.

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Ubiquitin and the molecular pathology of neurodegenerative diseases.

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Hypothesis: can N-acetylcysteine be beneficial in Parkinson's disease?

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The Role of Cyclooxygenase-2 in Inflammation

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Alpha synuclein in neurodegenerative disorders: murderer or accomplice?

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7 January 2021

Cyclopentenone prostaglandins of the J series inhibit the ubiquitin isopeptidase activity of the proteasome pathway

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7 January 2021

Human brain prostaglandin D synthase has been evolutionarily differentiated from lipophilic-ligand carrier proteins

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7 January 2021

The early induction of cyclooxygenase 2 associated with neurofibrillary degeneration in brains of patients with Fukuyama-type congenital muscular dystrophy

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7 January 2021

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Cyclooxygenase-2 expression is increased in frontal cortex of Alzheimer's disease brain

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7 January 2021

Prostaglandins act as neurotoxin for differentiated neuroblastoma cells in culture and increase levels of ubiquitin and beta-amyloid

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7 January 2021

Proteasome inhibition in neuronal cells induces a proinflammatory response manifested by upregulation of cyclooxygenase-2, its accumulation as ubiquitin conjugates, and production of the prostaglandin PGE(2).

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7 January 2021

Cyclooxygenase-2 is induced globally in infarcted human brain

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7 January 2021

Oxidative metabolites of 5-S-cysteinyldopamine inhibit the alpha-ketoglutarate dehydrogenase complex: possible relevance to the pathogenesis of Parkinson's disease

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7 January 2021

Cellular defenses against unfolded proteins: a cell biologist thinks about neurodegenerative diseases

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7 January 2021

Protein turnover by the proteasome in aging and disease.

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7 January 2021

Cyclooxygenases: structural, cellular, and molecular biology

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7 January 2021

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7 January 2021

Cyclopentenone prostaglandins: new insights on biological activities and cellular targets

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7 January 2021

Toxic proteins in neurodegenerative disease

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7 January 2021

Inhibition of the cyclooxygenase isoenzymes COX-1 and COX-2 provide neuroprotection in the MPTP-mouse model of Parkinson's disease

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7 January 2021

Prostaglandin D2 and sleep regulation

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7 January 2021

A subset of NSAIDs lower amyloidogenic Abeta42 independently of cyclooxygenase activity

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7 January 2021

Inflammation in neurodegenerative disease--a double-edged sword

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7 January 2021

Expression of a mitogen-inducible cyclooxygenase in brain neurons: regulation by synaptic activity and glucocorticoids

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7 January 2021

Marked increase in cyclooxygenase-2 in ALS spinal cord: implications for therapy

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7 January 2021

Reduced incidence of AD with NSAID but not H2 receptor antagonists: the Cache County Study

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7 January 2021

10.1016/S1357-2725(02)00384-9

Identifiers

DOI

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6 August 2017

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